A meta-analysis of status and risk factors of central venous catheter-associated bloodstream infection in ICU patients

WANG Dao-xin; LIU Nan; SHI Ze-yuan; DING Nan-nan; FENG Chun-qian; ZHAO Wen-li

doi:10.16766/j.cnki.issn.1674-4152.002745

Volume 20 Issue 11

Nov. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(11): 1954-1959

WANG Dao-xin, LIU Nan, SHI Ze-yuan, DING Nan-nan, FENG Chun-qian, ZHAO Wen-li. A meta-analysis of status and risk factors of central venous catheter-associated bloodstream infection in ICU patients[J]. Chinese Journal of General Practice, 2022, 20(11): 1954-1959. doi: 10.16766/j.cnki.issn.1674-4152.002745

Citation:

WANG Dao-xin, LIU Nan, SHI Ze-yuan, DING Nan-nan, FENG Chun-qian, ZHAO Wen-li. A meta-analysis of status and risk factors of central venous catheter-associated bloodstream infection in ICU patients[J]. Chinese Journal of General Practice, 2022, 20(11): 1954-1959. doi: 10.16766/j.cnki.issn.1674-4152.002745

Citation:

WANG Dao-xin, LIU Nan, SHI Ze-yuan, DING Nan-nan, FENG Chun-qian, ZHAO Wen-li. A meta-analysis of status and risk factors of central venous catheter-associated bloodstream infection in ICU patients[J]. Chinese Journal of General Practice, 2022, 20(11): 1954-1959. doi: 10.16766/j.cnki.issn.1674-4152.002745

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A meta-analysis of status and risk factors of central venous catheter-associated bloodstream infection in ICU patients

doi: 10.16766/j.cnki.issn.1674-4152.002745

1.
School of Nursing and Health, Henan University, Kaifeng, Henan 475004, China

Funds:

81872584

212102310683

Received Date: 2022-03-09
Available Online: 2022-12-30

Abstract

Abstract

Objective To analyse the risk factors of catheter-related infection in ICU patients. Methods Related articles on independent risk factors of central venous catheter-related bloodstream infection in ICU patients were searched in PubMed, Web of Science, Cochrane Library, CNKI, Wanfang, CBM, EBSCO and other databases. Outcomes were combined, and meta-analysis and sensitivity analysis were performed using RevMan 5.3 software. Results A total of 13 studies were included, including 12 283 patients and 773 infected patients. The infection rate was 6.29%. Nine risk factors were as follow: catheter indwelling days ≥7 days (OR=5.30, 95% CI: 3.39-8.27), diabetes mellitus (OR=21.15, 95% CI: 11.45-39.08), antibiotic use before catheterisation (OR=6.63, 95% CI: 5.12-8.58), advanced age (OR=3.01, 95% CI: 2.74-3.31), puncture frequency of >2 times (OR=60.10, 95% CI: 30.63-117.94), high APACHEⅡ score (OR=16.07, 95% CI: 8.97-28.77), femoral vein catheterisation (OR=12.41, 95% CI: 3.82-40.30), male (OR=7.93, 95% CI: 3.69-17.04), emergency surgery (OR=8.12, 95% CI: 3.43-19.19), all P < 0.05. Conclusions The main risk factors for central catheter-related bloodstream infection in ICU patients are catheter indwelling days ≥7 days, diabetes mellitus, antibiotics before catheterisation, age of > 55 years, catheterisation frequecy of >2 times, high APACHEⅡ score, femoral vein as the indwelling site, male and emergency surgery. Clinical attention should be paid to high-risk groups and related risk factors, and effective intervention measures should be taken to reduce the occurrence of central catheter-related bloodstream infection.
- ICU,
- Catheter-related bloodstream infection,
- Risk factors,
- Meta analysis

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References(27)

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