Volume 20 Issue 12
Dec.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(12): 2022-2024
LIU Ru, YAN Shan-jun, DENG Min, WANG Jian-chao, KE Xi-quan, ZHU Yu, GU Lin. Clinical effects of endoscopic minimally invasive and surgical treatment of gastric stromal tumours[J]. Chinese Journal of General Practice, 2022, 20(12): 2022-2024. doi: 10.16766/j.cnki.issn.1674-4152.002760
Citation: LIU Ru, YAN Shan-jun, DENG Min, WANG Jian-chao, KE Xi-quan, ZHU Yu, GU Lin. Clinical effects of endoscopic minimally invasive and surgical treatment of gastric stromal tumours[J]. Chinese Journal of General Practice, 2022, 20(12): 2022-2024. doi: 10.16766/j.cnki.issn.1674-4152.002760
shu

Clinical effects of endoscopic minimally invasive and surgical treatment of gastric stromal tumours

doi: 10.16766/j.cnki.issn.1674-4152.002760

  • Department of Gastroenterology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 201904a07020022

  • Received Date: 2022-07-11
    Available Online: 2023-02-07
    Abstract
  •   Objective  To observe and compare the clinical effects of endoscopic minimally invasive surgery and surgical surgery on the treatment of gastric stromal tumours with tumour diameter ≤4 cm.  Methods  Patients with gastric stromal tumour treated at the First Affiliated Hospital of Bengbu Medical College from March 2019 to March 2021 were retrospectively analysed and divided into endoscopic and surgical groups based on the different treatment methods. The general data, perioperative indicators, postoperative complications and recurrence in the two groups were analysed and compared.  Results  A total of 128 patients with confirmed gastric stromal tumours were included. Exactly 98 cases were included in the endoscopic group, including 57 cases of endoscopic submucosal dissection, 32 cases of endoscopic full-thickness resection, 5 cases of endoscopic submucosal tunneling for tumor dissection and 4 cases of endoscopic submucosal excision. The surgical group comprised 30 cases, including 4 cases of open surgery, 10 cases of laparoscopic wedge resection and 16 cases of laparoscopic subtotal gastrectomy. No significant differences were observed in the gender, age, body mass index (BMI), diabetes and other general data between the two groups (P>0.05). The most common tumor sites in the two groups were fundus, body, antrum and cardia. No significant differences were observed in tumour diameter, immunohistochemical parameters (positive rates of CD117, DOG-1 and CD34), NIH risk and mitotic number between the two groups (all P>0.05). The operation time, postoperative first oral feeding time, postoperative hospital stay and hospitalisation cost of the endoscopic group were significantly lower than those of the surgical group [(63.99±35.19) h vs. (125.10±49.33) h, (2.63±1.03) d vs. (4.90±2.23) d, (6.43±1.54) d vs. (7.67±1.92) d, (27 048.44±4 613.41) yuan vs. (49 022.00±9 795.40) yuan, all P < 0.05]. One case of delayed bleeding occurred in the endoscopic group, and one case of abdominal infection occurred in the surgical group. No serious postoperative complications, such as anastomotic leakage and peritonitis, were observed. During the follow-up period of 12-36 months, no recurrence was found in the two groups.  Conclusion  For gastric stromal tumours with tumour diameter ≤4 cm, endoscopic treatment can achieve comparable short-term and long-term efficacies with surgery, accelerate postoperative recovery, shorten postoperative hospital stay and reduce medical costs.

     

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