Volume 21 Issue 1
Jan.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(1): 57-61
HUANG Zhen, ZHAO Chun, YANG Zhi-yong, XU Gang, WANG Kai-ming. Therapeutic efficacy of gelatin sponge to block bone cement leakage during percutaneous vertebroplasty[J]. Chinese Journal of General Practice, 2023, 21(1): 57-61. doi: 10.16766/j.cnki.issn.1674-4152.002811
Citation: HUANG Zhen, ZHAO Chun, YANG Zhi-yong, XU Gang, WANG Kai-ming. Therapeutic efficacy of gelatin sponge to block bone cement leakage during percutaneous vertebroplasty[J]. Chinese Journal of General Practice, 2023, 21(1): 57-61. doi: 10.16766/j.cnki.issn.1674-4152.002811
shu

Therapeutic efficacy of gelatin sponge to block bone cement leakage during percutaneous vertebroplasty

doi: 10.16766/j.cnki.issn.1674-4152.002811
  • 1.

    Department of Orthopedics, Third People' s Hospital of Bengbu City, Bengbu, Anhui 233000, China

Funds:

 KJ2021A0802

  • Received Date: 2022-03-19
    Available Online: 2023-04-07
    Abstract
  •   Objective  To investigate the therapeutic efficacy of bone cement leakage after gelatin sponge plugging in percutaneous vertebroplasty in osteoporotic vertebral compression fracture.  Methods  The study retrospectively enrolled 46 patients with osteoporotic vertebral compression fracture, who were admitted to the Department of Orthopedics of Third People ' s Hospital of Bengbu City from February 2020 to February 2022. All patients were randomly divided into gelatin sponge group and control group, with 23 patients in each group. Patients were followed up for 1 months after surgery. The operation time, bone cement injection volume, Cobb angle, Beck index, Oswestry disability index (ODI), and bone cement diffusion coefficient were recorded and analyzed before operation, 1 day after operation, and 1 month after operation. The therapeutic efficacy of gelatin sponge application on bone cement leakage during percutaneous vertebroplasty was evaluated, and the pain relief effect of postoperative patients was evaluated by visual analog scale.  Results  The gelatin sponge group had one case of cement leakage (4.35%), while 8 patients (34.78%) had cement penetration in the control group, the difference between the two groups was statistically significant (χ2=4.973, P=0.026). The cement diffusion coefficient of gelatin sponge group and control group were (77.57±0.72)% and (58.20±0.85)%, respectively, with a statistically significant difference (t=83.392, P < 0.001). Before operation, 1 day after operation, and 1 month after operation, there were no significant differences in ODI, VAS score, Cobb angle, and Beck index between groups (all P>0.05). However, there were statistically significant differences in each index group 1 day after operation, 1 month after operation and before operation (all P < 0.05).  Conclusion  Gelatin sponge plugging can significantly reduce the incidence of leakage caused by cement diffusion during percutaneous vertebroplasty, and improve the diffusion effect of bone cement in diseased vertebrae. Gelatin sponge has a series of advantages such as easy material acquisition, low price, and easy operation, and has certain promotion value in clinical work.

     

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