Volume 21 Issue 2
Feb.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(2): 324-328
SHEN Yuan-juan, DAI Zheng-xiang, LI Ju-yun, WU Xiao-yu, WANG Sai-nan, WANG Qing. Incidence and influencing factors of high-output ileostomy in adults: a meta-analysis[J]. Chinese Journal of General Practice, 2023, 21(2): 324-328. doi: 10.16766/j.cnki.issn.1674-4152.002874
Citation: SHEN Yuan-juan, DAI Zheng-xiang, LI Ju-yun, WU Xiao-yu, WANG Sai-nan, WANG Qing. Incidence and influencing factors of high-output ileostomy in adults: a meta-analysis[J]. Chinese Journal of General Practice, 2023, 21(2): 324-328. doi: 10.16766/j.cnki.issn.1674-4152.002874
shu

Incidence and influencing factors of high-output ileostomy in adults: a meta-analysis

doi: 10.16766/j.cnki.issn.1674-4152.002874
  • 1.

    School of Nursing, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210000, China

Funds:

 82174466

  • Received Date: 2022-07-13
    Available Online: 2023-04-20
    Abstract
  •   Objective  To perform a systematic review of the incidence and influencing factors of high-output ileostomy (HOI).  Methods  Computer searched CBM, CNKI, WanFang Data, VIP database, PubMed, Web of Science, EMbase, and the Cochrane Library for research literature on factors affecting the occurrence of HOI. The search time was set from the establishment of the database to May 2022. Two researchers screened the literature and extracted data independently. The Newcastle-Ottawa Scale was used to evaluate the risk of bias of the literature. Statistical analysis was performed using Review Manager 5.4.  Results  A total of nine studies were included, all with a score of 7 or above. In addition, 1 844 patients had ileostomy, including 393 patients with HOI. The overall incidence of HOI in patients with ileostomy was 23% (95% CI: 0.18-0.28, P < 0.001). Results of influencing factor analysis showed that inflammatory bowel disease (OR=16.17, 95% CI: 7.00-37.38, P < 0.001), diabetes (OR=13.69, 95% CI: 6.42-29.20, P < 0.001), chemoradiotherapy (OR=4.50, 95% CI: 1.29-15.67, P=0.020) and postoperative outlet obstruction (OR=3.77, 95% CI: 1.57-9.07, P=0.003) were the influencing factors of HOI.  Conclusion  Inflammatory bowel disease, diabetes, radiotherapy, chemoradiotherapy and postoperative outlet obstruction are the influencing factors of HOI, but the number of existing studies is small, and most of them are small sample studies. In addition, the diagnostic criteria of HOI are inconsistent, which affects the results of meta-analysis to a certain extent. Therefore, the above-mentioned conclusions must be further verified.

     

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