Volume 21 Issue 3
Mar.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(3): 377-380
ZHAO Xue, LIU Guomei, ZHANG Wenhui, WAN Xiaochuan, WANG Wenbin, WU Yile. Influencing factors of infection or colonization with multidrug-resistant organisms in ICU based on active screening[J]. Chinese Journal of General Practice, 2023, 21(3): 377-380. doi: 10.16766/j.cnki.issn.1674-4152.002887
Citation: ZHAO Xue, LIU Guomei, ZHANG Wenhui, WAN Xiaochuan, WANG Wenbin, WU Yile. Influencing factors of infection or colonization with multidrug-resistant organisms in ICU based on active screening[J]. Chinese Journal of General Practice, 2023, 21(3): 377-380. doi: 10.16766/j.cnki.issn.1674-4152.002887
shu

Influencing factors of infection or colonization with multidrug-resistant organisms in ICU based on active screening

doi: 10.16766/j.cnki.issn.1674-4152.002887
  • 1.

    Department of Scientific Research, the Fourth Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230012, China

Funds:

 82202572

 KJ2021A0332

 KJ2021A0321

 2020xkj042

  • Received Date: 2022-05-09
    Available Online: 2023-04-19
    Abstract
  •   Objective  To investigate the incidence and influencing factors of multidrug-resistant organisms (MDROs) infection or colonization in the intensive care unit (ICU), so as to provide scientific basis for MDROs prevention and control measures.  Methods  A total of 466 ICU patients admitted to the Fourth Affiliated Hospital of Anhui Medical University from July 2019 to June 2021 were selected as the research objects. The occurrence of MDROs nosocomial infection or colonization was monitored by means of active screening and microbiological cultures according to clinical status. Multivariate logistic regression analysis was performed in examining the influencing factors of MDROs infection or colonization.  Results  Among 466 ICU inpatients, MDROs nosocomial infection or colonization was detected in 161 cases (34.55%), including 41 cases (8.80%) of MDROs infection and 120 cases (25.75%) of MDROs colonization. Multivariate logistic regression analysis showed that more than 7 days of ICU hospitalization, high acute physiology and chronic health evaluation (APACHE) Ⅱ score, invasive mechanical ventilation, more than 3 kinds of combined antibiotics, steroid use and having a prior bed occupant with MDROs were risk factors for MDROs infection or colonization in ICU inpatients(all P < 0.05).  Conclusion  ICU inpatients have a high incidence of MDROs nosocomial infection or colonization, which is related to multiple factors. Comprehensive measures should be taken to reduce the incidence of MDROs nosocomial infection or colonization.

     

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