Volume 21 Issue 3
Mar.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(3): 401-404
WANG Yiyi, LI Xiaohong, LIU Peng, WANG Yahui, LIN Xuewu. Efficacy observation of ultrasound-guided paravertebral nerve block combined with lidocaine gel plaster in the treatment of postherpetic neuralgia[J]. Chinese Journal of General Practice, 2023, 21(3): 401-404. doi: 10.16766/j.cnki.issn.1674-4152.002893
Citation: WANG Yiyi, LI Xiaohong, LIU Peng, WANG Yahui, LIN Xuewu. Efficacy observation of ultrasound-guided paravertebral nerve block combined with lidocaine gel plaster in the treatment of postherpetic neuralgia[J]. Chinese Journal of General Practice, 2023, 21(3): 401-404. doi: 10.16766/j.cnki.issn.1674-4152.002893
shu

Efficacy observation of ultrasound-guided paravertebral nerve block combined with lidocaine gel plaster in the treatment of postherpetic neuralgia

doi: 10.16766/j.cnki.issn.1674-4152.002893

  • Department of Anesthesiology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 2020ZYRC104

  • Received Date: 2022-05-31
    Available Online: 2023-04-19
    Abstract
  •   Objective  To analyze the clinical efficacy and safety of ultrasound-guided paravertebral nerve block combined with lidocaine gel plaster in the treatment of chest and back postherpetic neuralgia.  Methods  A total of 80 patients with thoracolumbar post-herpetic neuralgia admitted to the Department of Pain, the First Affiliated Hospital of Bengbu Medical College from October 2020 to December 2021 were randomly divided into control group and treatment group according to the random number table method, with 40 patients in each group. The control group was treated with ultrasound-guided paravertebral block, and the treatment group was treated with ultrasound-guided paravertebral block combined with lidocaine gel plaster. The visual analog scale (VAS) score and Pittsburgh sleep quality index (PSQI), the dosage of pregabalin and the incidence of adverse reactions were compared between the two groups before treatment (T0), 1 week after treatment (T1), 2 weeks after treatment (T2), 3 weeks after treatment (T3), 4 weeks after treatment (T4) and 8 weeks after treatment (T8).  Results  The VAS scores of treatment groups at T1, T2, T3, T4 and T8 were (5.20±0.82) points, (3.90±0.77) points, (3.58±0.76) points, (2.62±0.69) points, (1.98±0.48) points respectively, which were lower than those in the control group [(6.03±1.07) points, (4.95±0.81) points, (4.03±0.83) points, (3.05±0.76) points and (2.55±0.50) points, all P < 0.05]. The PSQI of the treatment group was significantly lower than that of the control group at the same time point, and the difference was statistically significant (all P < 0.05). The effective rate of the treatment group was 77.5% (31/40), better than that of the control group [50.0% (20/40)], and the difference was statistically significant (P < 0.05).  Conclusion  Ultrasound-guided paravertebral nerve block combined with lidocaine gel patch can effectively relieve postherpetic neuralgia and improve sleep quality of patients with good safety.

     

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    • References(20)
  • [1]
    黄爱苹, 谷桢, 薛纯纯, 等. 电针结合刺络拔罐治疗带状疱疹后遗神经痛的临床疗效评价[J]. 中华全科医学, 2020, 18(5): 835-838. doi: 10.16766/j.cnki.issn.1674-4152.001369

    HUANG A P, GU Z, XUE C C, et al. Clinical evaluation of electroacupuncture combined with cupping therapy in the treatment of postherpetic neuralgia[J]. Chinese Journal of General Practice, 2020, 18(5): 835-838. doi: 10.16766/j.cnki.issn.1674-4152.001369
    [2]
    张静月, 张鹏娇, 孙东光, 等. 普瑞巴林联合皮内注射治疗急性带状疱疹性疼痛及带状疱疹后神经痛的临床疗效研究[J]. 河北医学, 2019, 25(9): 1520-1523. doi: 10.3969/j.issn.1006-6233.2019.09.029

    ZHANG J Y, ZHANG P J, SUN D G, et al. Clinical efficacy of pregabalin combined with intradermal injection in the treatment of acute herpetic pain and postherpetic neuralgia[J]. Hebei Medicine, 2019, 25(9): 1520-1523. doi: 10.3969/j.issn.1006-6233.2019.09.029
    [3]
    曹阳, 岳侃, 张金鑫, 等. 超声引导下竖脊肌平面阻滞联合普瑞巴林对带状疱疹后神经痛的疗效分析[J]. 中华医学杂志, 2019, 99(37): 2907-2911. doi: 10.3760/cma.j.issn.0376-2491.2019.37.007

    CAO Y, YUE K, ZHANG J X, et al. Ultrasound-guided erector spinae plane block combined with pregabalin for post-herpetic neuralgia[J]. National Medical Journal of China, 2019, 99(37): 2907-2911. doi: 10.3760/cma.j.issn.0376-2491.2019.37.007
    [4]
    刘韦辰, 王雨彤, 张达颖, 等. 带状疱疹后神经痛病人负性情绪的影响因素分析[J]. 中国疼痛医学杂志, 2022, 28(7): 545-548, 554. doi: 10.3969/j.issn.1006-9852.2022.07.012

    LIU W C, WANG Y T, ZHANG D Y, et al. Influencing factors of negative emotions in patients with postherpetic neuralgia[J]. Chinese Journal of Pain Medicine, 2022, 28(7): 545-548, 554. doi: 10.3969/j.issn.1006-9852.2022.07.012
    [5]
    NGO A L, URITS I, YILMAZ M, et al. Postherpetic neuralgia: Current evidence on the topical film-forming spray with bupivacaine hydrochloride and a review of available treatment strategies[J]. Adv Ther, 2020, 37(5): 2003-2016. doi: 10.1007/s12325-020-01335-9
    [6]
    GROSS G E, EISERT L, DOERR H W, et al. S2k guidelines for the diagnosis and treatment of herpes zoster and postherpetic neuralgia[J]. J Dtsch Dermatol Ges, 2020, 18(1): 55-78.
    [7]
    刘宋磊, 姚明, 徐龙生, 等. CT引导背根节射频治疗胸腹部带状疱疹后神经痛影响因素分析[J]. 中华全科医学, 2020, 18(11): 1807-1810. doi: 10.16766/j.cnki.issn.1674-4152.001624

    LIU S L, YAO M, XU L S, et al. Analysis of influencing factors of CT-guided radiofrequency treatment of postherpetic neuralgia in chest and abdomen[J]. Chinese Journal of General Practice, 2020, 18(11): 1807-1810. doi: 10.16766/j.cnki.issn.1674-4152.001624
    [8]
    周围神经病理性疼痛中国专家共识编委会. 周围神经病理性疼痛诊疗中国专家共识[J]. 中国疼痛医学杂志, 2020, 26(5): 321-328. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202005003.htm

    Editorial committee of Chinese expert consensus on peripheral neuropathic pain. Chinese expert consensus on the diagnosis and treatment of peripheral neuropathic pain[J]. Chinese Journal of Pain Medicine, 2020, 26(5): 321-328. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202005003.htm
    [9]
    汪婷, 陈立平, 季云晶, 等. 脉冲射频联合抗抑郁药治疗老年带状疱疹后神经痛的临床疗效[J]. 中国疼痛医学杂志, 2021, 27(9): 669-675. doi: 10.3969/j.issn.1006-9852.2021.09.006

    WANG T, CHEN L P, JI Y J, et al. Clinical efficacy of pulsed radiofrequency combined with antidepressant in the treatment of senile postherpetic neuralgia[J]. Chinese Journal of Pain Medicine, 2021, 27(9): 669-675. doi: 10.3969/j.issn.1006-9852.2021.09.006
    [10]
    皮治兵, 林海, 彭宇, 等. 加巴喷丁辅助治疗颈肩及颜面部带状疱疹后神经痛及对T淋巴细胞的影响[J]. 中华全科医学, 2020, 18(1): 45-47. doi: 10.16766/j.cnki.issn.1674-4152.001164

    PI Z B, LIN H, PENG Y, et al. Effect of gabapentin on the treatment of postherpetic neuralgia of neck, shoulder and face and its effect on T lymphocytes[J]. Chinese Journal of General Practice, 2020, 18(1): 45-47. doi: 10.16766/j.cnki.issn.1674-4152.001164
    [11]
    ZHAO P, MEI L. A clinical study of paraspinal nerve block on treatment of herpes zoster under ultrasonic guidance[J]. Neurochirurgie, 2019, 65(6): 382-386. doi: 10.1016/j.neuchi.2019.06.007
    [12]
    ZHENG C J, WANG J Y, XIE S X. Ultrasound-Guided thoracic paravertebral nerve block on postoperative pain, quality of life, and recovery in patients with non-small-cell lung cancer[J]. Biomed Res Int, 2021, 2021: 6692815. DOI: 10.1155/2021/6692815.
    [13]
    赵秀凤, 刘川. 超声引导下胸椎旁阻滞在胸腔镜肺叶切除术中的应用[J]. 现代医药卫生, 2019, 35(13): 1978-1980, 1983. https://www.cnki.com.cn/Article/CJFDTOTAL-XYWS201913019.htm

    ZHAO X F, LIU C. Application of ultrasound-guided thoracic paravertebral block in thoracoscopic lobectomy[J]. Modern Medicine & Health, 2019, 35(13): 1978-1980, 1983. https://www.cnki.com.cn/Article/CJFDTOTAL-XYWS201913019.htm
    [14]
    王兴耀, 钱金桥. 超声引导单点和双点椎旁神经阻滞在胸腔镜术患者的镇痛比较[J]. 昆明医科大学学报, 2020, 41(8): 46-51. https://www.cnki.com.cn/Article/CJFDTOTAL-KMYX202008009.htm

    WANG X Y, QIAN J Q. Comparison of ultrasound-guided single point and double point paravertebral nerve block in patients undergoing thoracoscopic surgery[J]. Journal of Kunming Medical University, 2020, 41(8): 46-51. https://www.cnki.com.cn/Article/CJFDTOTAL-KMYX202008009.htm
    [15]
    MAKHARITA M Y, AMR Y M. Effect of repeated paravertebral injections with local anesthetics and steroids on prevention of post-herpetic neuralgia[J]. Pain Physician, 2020, 23(6): 565-572.
    [16]
    LIN C S, LIN Y C, LAO H C, et al. Interventional treatments for postherpetic neuralgia: a systematic review[J]. Pain Physician, 2019, 22(3): 209-228.
    [17]
    刘劲洲, 蒋宗滨. 电压门控离子通道与带状疱疹后神经痛[J]. 中国疼痛医学杂志, 2021, 27(3): 208-211. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202103011.htm

    LIU J Z, JIANG Z B. Voltage-gated ion channels and postherpetic neuralgia[J]. Chinese Journal of Pain Medicine, 2021, 27(3): 208-211. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202103011.htm
    [18]
    GUDIN J, NALAMACHU S. Utility of lidocaine as a topical analgesic and improvements in patch delivery systems[J]. Postgrad Med, 2020, 132(1): 28-36.
    [19]
    刘奎玲, 李晓强, 孙雪华. 利多卡因凝胶贴膏联合加巴喷丁治疗带状疱疹后神经痛[J]. 中国疼痛医学杂志, 2021, 27(5): 386-389. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202105018.htm

    LIU K L, LI X Q, SUN X H. Lidocaine gel paste combined with gabapentin for the treatment of postherpetic neuralgia[J]. Chinese Journal of Pain Medicine, 2019, 27(5): 386-389. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202105018.htm
    [20]
    焦文强, 黄译平, 黄科昌, 等. 利多卡因凝胶贴膏外敷在家兔皮肤和背根神经节中药物分布规律[J]. 中国疼痛医学杂志, 2022, 28(4): 306-310. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202204012.htm

    JIAO W Q, HUANG Y P, HUANG K C, et al. Effect of lidocaine gel on skin and dorsal root ganglion of rabbits[J]. Chinese Journal of Pain Medicine, 2022, 28(4): 306-310. https://www.cnki.com.cn/Article/CJFDTOTAL-ZTYZ202204012.htm
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