Volume 21 Issue 3
Mar.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(3): 522-525
WANG Runping, ZHENG Xiaofen, CHEN Yingqiu, CHEN Aiwu, JIN Zhizhi, LI Yuxi. Risk factors and preventive nursing measures of acute leukaemia complicated with respiratory tract infection in children[J]. Chinese Journal of General Practice, 2023, 21(3): 522-525. doi: 10.16766/j.cnki.issn.1674-4152.002922
Citation: WANG Runping, ZHENG Xiaofen, CHEN Yingqiu, CHEN Aiwu, JIN Zhizhi, LI Yuxi. Risk factors and preventive nursing measures of acute leukaemia complicated with respiratory tract infection in children[J]. Chinese Journal of General Practice, 2023, 21(3): 522-525. doi: 10.16766/j.cnki.issn.1674-4152.002922
shu

Risk factors and preventive nursing measures of acute leukaemia complicated with respiratory tract infection in children

doi: 10.16766/j.cnki.issn.1674-4152.002922

  • Department of Pediatric Hematology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

Funds:

 GF21G020006

 Y2020458

  • Received Date: 2022-05-11
    Available Online: 2023-04-19
    Abstract
  •   Objective  To analyse the risk factors of acute leukaemia (AL) complicated with respiratory tract infection in children and to propose preventive nursing measures based on the results, thereby providing reference for clinical treatment.  Methods  A retrospective analysis was performed on 140 paediatric AL patients admitted to the Second Affiliated Hospital of Wenzhou Medical University from February 2018 to February 2021, who were divided into the respiratory tract infection group (72 cases) and non-respiratory tract infection group (68 cases). Relevant clinical data of the patients were collected to analyse the risk factors affecting children with AL complicated with respiratory tract infection, and the preventive nursing measures were proposed.  Results  Severe anaemia, white blood cell count >10×109/L or < 2×109/L, platelet < 20×109/L, hypoproteinaemia, prolonged hospital stay, chemotherapy regimen and prophylactic use of antibiotics were the influencing factors of paediatric leukaemia complicated with respiratory tract infection (all P < 0.05). Multivariate logistic regression analysis showed that severe anaemia (OR=2.440, 95% CI: 1.073-5.546), platelet < 20×109/L (OR=1.972, 95% CI: 1.061-3.663), hypoproteinaemia (OR=2.959, 95% CI: 1.115-7.853) and IA chemotherapy regimen (OR=3.799, 95% CI: 1.207-11.957) were independent risk factors for AL complicated with respiratory tract infection in children.  Conclusion  The risk factors of children with AL complicated with respiratory tract infection include severe anaemia, platelet < 20×109/L, hypoproteinaemia and IA chemotherapy regimen, and preventive nursing measures should be taken in accordance with the above-mentioned risk factors in clinic.

     

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