Volume 21 Issue 4
Apr.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(4): 655-658
NI Juanjuan, SUN Yixue, SHI Yan, LI Yang, ZHU Yu. Contrast-enhanced ultrasound combined quantitative analysis of the parameters of clinical guidance value in the diagnosis and treatment of inflammatory bowel disease activity[J]. Chinese Journal of General Practice, 2023, 21(4): 655-658. doi: 10.16766/j.cnki.issn.1674-4152.002953
Citation: NI Juanjuan, SUN Yixue, SHI Yan, LI Yang, ZHU Yu. Contrast-enhanced ultrasound combined quantitative analysis of the parameters of clinical guidance value in the diagnosis and treatment of inflammatory bowel disease activity[J]. Chinese Journal of General Practice, 2023, 21(4): 655-658. doi: 10.16766/j.cnki.issn.1674-4152.002953
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Contrast-enhanced ultrasound combined quantitative analysis of the parameters of clinical guidance value in the diagnosis and treatment of inflammatory bowel disease activity

doi: 10.16766/j.cnki.issn.1674-4152.002953

  • Department of Ultrasound Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2020A0582

  • Received Date: 2022-08-23
    Available Online: 2023-05-31
    Abstract
  •   Objective  To study the effectiveness of the combined use of contrast-enhanced ultrasound (CEUS) and quantitative analysis parameters for the diagnosis of inflammatory bowel disease (IBD) in terms of inflammatory activity.  Methods  A total of 27 inpatients with IBD admitted to the Department of Gastroenterology of the First Affiliated Hospital of Bengbu Medical College and the outpatient follow-up IBD patients were selected from November 2021 to August 2022. They were divided into ulcerative colitis (UC group, 13 cases) and Crohn ' s disease (CD group, 14 cases) groups according to their pathology and clinical diagnosis. According to the CD activity index score and the modified Mayo scale, the two groups of patients were divided into active and inactive groups. Intestinal wall thickness, power Doppler image (PDI) blood flow, CEUS enhancement mode and quantitative parameters [peak intensity (PI), ascending slope (AS), arrival time (AT), time to peak (TTP)] were compared between active and inactive groups.  Results  The intestinal wall thickness in the active group of UC was greater than that in the inactive group [(8.4±1.3) mm vs. (5.2±1.0) mm, t=4.810, P=0.001]. The intestinal wall thickness in the active group of CD was greater than that in the inactive group [(8.2±1.8) mm vs. (5.1±1.2) mm, t=3.850, P=0.002]. There were significant differences in the grading of intestinal wall blood flow and the enhancement pattern of CEUS between the active and inactive UC groups (all P < 0.05). There were significant differences in PI and AT between the active and inactive UC groups (both P < 0.05). There were significant differences in PI and TTP between the active and inactive CD groups (both P < 0.05).  Conclusion  The intestinal wall thickness, PDI, CEUS enhancement pattern and the quantitative analysis parameters PI, AT and TTP are all relevant to the diagnosis and assessment of inflammatory bowel disease activity.

     

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    • References(21)
  • [1]
    陈瑜君, 陈淑玲, 谢晓燕. 胃肠道超声在炎症性肠病中的应用与新进展[J]. 中华炎性肠病杂志, 2019, 3(4): 313-315.

    CHEN Y J, CHEN S L, XIE X Y. Applications and progress of gastrointestinal ultrasound in inflammatory bowel disease[J]. Chinese Journal of Inflammatory Bowel Diseases, 2019, 3(4): 313-315.
    [2]
    西永忠. 腹部超声在炎性肠病活动期中的诊断价值[J]. 中国肛肠病杂志, 2019, 39(10): 25-26. https://www.cnki.com.cn/Article/CJFDTOTAL-GCBZ201910013.htm

    XI Y Z. The Value of Abdominal Ultrasonograpy in Diagnosing Active Stage of Inflammatory Bowel Disease[J]. Chinese Journal of Coloproctology, 2019, 39(10): 25-26. https://www.cnki.com.cn/Article/CJFDTOTAL-GCBZ201910013.htm
    [3]
    吴越, 陈秋雨, 陈中霞, 等. 经腹肠道超声在炎症性肠病诊断与评估中的应用和进展[J]. 胃肠病学, 2021, 26(1): 57-61. https://www.cnki.com.cn/Article/CJFDTOTAL-WIEC202101011.htm

    WU Y, CHEN Q Y, CHEN Z X, et al. Application and Progress of Trans-abdominal Bowel Ultrasound for Diagnosis and Assessment of Inflammatory Bowel Disease[J]. Chinese Journal of Gastroenterology, 2021, 26(1): 57-61. https://www.cnki.com.cn/Article/CJFDTOTAL-WIEC202101011.htm
    [4]
    瞿庆红, 陈霞. 经腹彩色多普勒超声检查在溃疡性结肠炎早期诊断和活动性评估中的应用价值[J]. 中国现代医生, 2019, 57(8): 122-125. https://www.cnki.com.cn/Article/CJFDTOTAL-ZDYS201908036.htm

    QU Q H, CHEN X. Application value of transabdominal color Doppler ultrasound in early diagnosis and activity evaluation of ulcerative colitis[J]. China Modern Doctor, 2019, 57(8): 122-125. https://www.cnki.com.cn/Article/CJFDTOTAL-ZDYS201908036.htm
    [5]
    王韦力, 程文捷, 文艳玲, 等. 超声造影定量分析评估克罗恩病炎症活动程度的应用价值[J]. 中华医学超声杂志(电子版), 2019, 16(12): 949-955. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHCD201912012.htm

    WANG W L, CHENG W J, WEN Y L, et al. Contrast-enhanced ultrasound quantitative analysis for assessment of disease activity of Crohn′s disease[J]. Chinese Journal of Medical Ultrasound Celectronic Edition, 2019, 16(12): 949-955. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHCD201912012.htm
    [6]
    MEDELLIN A, MERRILL C, WILSON S R. Role of contrast-enhanced ultrasound in evaluation of the bowel[J]. Abdom Radiol(NY), 2018, 43(4): 918-933.
    [7]
    MACONI G, NYLUND K, RIPOLLES T, et al. EFSUMB recommendations and Clinical Guidelines for Intestinal Ultrasound (GIUS) in inflammatory bowel diseases [J]. Ultraschall Med, 2018, 39(3): 304-317. http://europepmc.org/abstract/MED/29566419
    [8]
    AHMED R, DEBIAN H, FAWZI M, et al. Diagnosis of inflammatory bowel disease by abdominal ultrasound and color Doppler techniques[J]. Curr Med Imaging, 2021, 17(9): 1085-1093. http://pubmed.ncbi.nlm.nih.gov/33397243/
    [9]
    SMITH R L, TAYLOR K M, FRIEDMAN A B, et al. Systematic review: clinical utility of gastrointestinal ultrasound in the diagnosis, assessment and management of patients with ulcerative colitis[J]. J Crohns Colitis, 2020, 14(4): 465-479. http://pubmed.ncbi.nlm.nih.gov/31562739/
    [10]
    丁诗思, 刘畅, 徐辉雄. 克罗恩病超声诊断的现状及进展[J]. 中华医学超声杂志(电子版), 2020, 17(10): 927-932. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHCD202010002.htm

    DING S S, LIU C, XU H X. Status quo and progress of ultrasound diagnosis of Crohn's disease[J]. Chinese Journal of Medical Ultrasound Celectronic Edition, 2020, 17(10): 927-932. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHCD202010002.htm
    [11]
    王海燕, 朱林林, 周如海, 等. 超声造影定量分析诊断乳头状甲状腺癌患者颈部淋巴结转移的效能分析[J]. 中华全科医学, 2019, 17(12): 2079-2082. doi: 10.16766/j.cnki.issn.1674-4152.001132

    WANG H Y, ZHU L L, ZHOU R H, et al. Effectiveness of contrast-enhanced ultrasound quantitative analysis in the diagnosis of cervical lymph node metastasis in patients with papillary thyroid carcinoma[J]. Chinese Journal of General Practice, 2019, 17(12): 2079-2082. doi: 10.16766/j.cnki.issn.1674-4152.001132
    [12]
    BETTENWORTH D, BOKEMEYER A, BAKER M, et al. Assessment of Crohn ' s disease-associated small bowel strictures and fibrosis on cross-sectional imaging: a systematic review[J]. Gut, 2019, 68(6): 1115-1126. http://www.xueshufan.com/publication/2927147343
    [13]
    于叶民, 顾林, 燕善军, 等. 溃疡性结肠炎患者JAM-1蛋白与STAT3信号通路关系的研究[J]. 中华全科医学, 2019, 17(3): 370-373. doi: 10.16766/j.cnki.issn.1674-4152.000684

    YU Y M, GU L, YAN S J, et al. Relationship between JAM-1 and STAT3 signaling pathway in patients with ulcerative colitis[J]. Chinese Journal of General Practice, 2019, 17(3): 370-373. doi: 10.16766/j.cnki.issn.1674-4152.000684
    [14]
    WILKENS R, HAGEMANN-MADSEN R H, PETERS D A, et al. Validity of contrast-enhanced ultrasonography and dynamic contrast-enhanced mr enterography in the assessment of transmural activity and fibrosis in Crohn ' s disease [J]. J Crohns Colitis, 2018, 12(1): 48-56.
    [15]
    GABBIADINI R, ZACHAROPOULOU E, FURFARO F, et al. Application of ultrasound elastography for assessing intestinal fibrosis in inflammatory bowel disease: fiction or reality?[J]. Curr Drug Targets, 2021, 22(3): 347-355. http://pubmed.ncbi.nlm.nih.gov/33213341/
    [16]
    CELIKYAY F, YUKSEKKAYA R, YUKSEKKAYA M, et al. Color doppler ultrasound assessment of clinical activity in inflammatory bowel disease[J]. Curr Med Imaging, 2021, 17(6): 741-750. http://www.researchgate.net/publication/348046426_Color_Doppler_Ultrasound_Assessment_of_Clinical_Activity_in_Inflammatory_Bowel_Disease
    [17]
    ZHANG F, MIAO L Y, GE H Y, et al. Usefulness of contrast-enhanced ultrasound in differentiating inflammatory bowel disease from colon cancer [J]. Ultrasound Med Biol, 2018, 44(1): 124-133.
    [18]
    KUNZE G, SEITZ K, MAUCH M, et al. Clinical ultrasound in inflammatory bowel disease[J]. Ultraschall Med, 2019, 40(2): 132-162.
    [19]
    HA C W Y, MARTIN A, SEPICH-POORE G D, et al. Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans[J]. Cell, 2020, 183(3): 666-683. http://www.xueshufan.com/publication/3088648928
    [20]
    GRAHAM D B, XAVIER R J. Pathway paradigms revealed from the genetics of inflammatory bowel disease[J]. Nature, 2020, 578(7796): 527-539. doi: 10.1038/s41586-020-2025-2
    [21]
    黄蓉, 曹莞婷, 范一宏, 等. 超声技术对炎症性肠病诊断的研究进展[J]. 中华超声影像学杂志, 2021, 30(4): 362-368.

    HUANG R, CAO G T, FAN Y H, et al. Progress in the diagnosis of inflammatory bowel disease by ultrasonography technique[J]. Chinese Journal of Ultrasonography, 2021, 30(4): 362-368.
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