Volume 21 Issue 4
Apr.  2023
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(4): 717-720
HE Chun, CHEN Lijuan, HUANG Fengmei, HOU Zhanghua. Clinical effect of interventional nursing measures for children with severe hypoxic ischemic encephalopathy treated with systemic mild hypothermia under invasive ventilation[J]. Chinese Journal of General Practice, 2023, 21(4): 717-720. doi: 10.16766/j.cnki.issn.1674-4152.002967
Citation: HE Chun, CHEN Lijuan, HUANG Fengmei, HOU Zhanghua. Clinical effect of interventional nursing measures for children with severe hypoxic ischemic encephalopathy treated with systemic mild hypothermia under invasive ventilation[J]. Chinese Journal of General Practice, 2023, 21(4): 717-720. doi: 10.16766/j.cnki.issn.1674-4152.002967
shu

Clinical effect of interventional nursing measures for children with severe hypoxic ischemic encephalopathy treated with systemic mild hypothermia under invasive ventilation

doi: 10.16766/j.cnki.issn.1674-4152.002967

  • NICU, First Affiliated Hospital of Xiangnan University, Chenzhou First People' s Hospital, Chenzhou, Hunan 423000, China

  • Received Date: 2022-08-11
    Available Online: 2023-05-31
    Abstract
  •   Objective  To explore the clinical efficacy of interventional nursing measures for children with severe hypoxic ischemic encephalopathy (HIE) treated with systemic mild hypothermia under invasive ventilation.  Methods  A total of 112 children with severe HIE admitted to Chenzhou First People ' s Hospital from February 2017 to February 2020 were selected as the research objects, and randomly divided into observation group and control group with 56 cases each group according to random number method. Both groups were treated with systemic mild hypothermia under invasive ventilation, the control group received routine nursing, and the observation group received interventional nursing measures on the basis of routine nursing. The clinical nursing effect of the two groups were observed and compared.  Results  The total incidence of complications such as urinary retention, pressure ulcers, epiduria, respiratory tract infection, arrhythmia and gastrointestinal bleeding was 26.79% in the observation group, and 83.93% in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group (P < 0.01). The hospitalization days of observation group and control group were (15.83±2.96) d and (22.92±2.87) d, respectively, and the hospitalization expenses were (16 295.31±175.67) yuan and (28 975.33±195.83) yuan, respectively. The hospitalization days and hospitalization expenses of the observation group were significantly lower than those of the control group (all P < 0.001).  Conclusion  Interventional nursing measures can effectively improve the clinical effect of systemic mild hypothermia under invasive ventilation for severe HIE children, reduce the risk of related complications during treatment, shorten the length of hospital stay and save treatment expenses, and it is worthy of clinical promotion and use.

     

    • FullText(HTML)
  • loading
    • References(16)
  • [1]
    肖晓林, 石锦, 吴阳敏, 等. 奥拉西坦联合脑苷肌肽治疗新生儿缺氧缺血性脑病的临床研究[J]. 现代药物与临床, 2018, 33(4): 842-846. https://www.cnki.com.cn/Article/CJFDTOTAL-GWZW201804027.htm

    XIAO X L, SHI J, WU Y M, et al. Clinical study on oxiracetam combined with cattle encephalon glycoside and ignotin in treatment of neonatal hypoxic ischemic encephalopathy[J]. Drugs & Clinic, 2018, 33(4): 842-846. https://www.cnki.com.cn/Article/CJFDTOTAL-GWZW201804027.htm
    [2]
    李建波, 吴文燊, 杜邦, 等. 中重度缺氧缺血性脑病新生儿亚低温治疗诱导期血流动力学的变化探讨[J]. 中国当代儿科杂志, 2021, 23(2): 133-137. https://www.cnki.com.cn/Article/CJFDTOTAL-DDKZ202102005.htm

    LI J B, WU W M, DU B, et al. mpact of mild hypothermia therapy on hemodynamics during the induction stage in neonates with moderate to severe hypoxic-ischemic encephalopathy[J]. Chinese Journal of Contemporary Pediatrics, 2021, 23(2): 133-137. https://www.cnki.com.cn/Article/CJFDTOTAL-DDKZ202102005.htm
    [3]
    陈少军, 周凤霞, 查志刚, 等. 心肌酶谱对中重度缺氧缺血性脑病新生儿亚低温治疗效果的评估价值[J]. 河北医药, 2021, 43(14): 2168-2170, 2174. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202114021.htm

    CHEN S J, ZHOU F X, ZHA Z G, et al. The application value of myocardial zymogram in evaluating the curative effects of mild hypothermia therapy on moderate or severe neonatal HIE[J]. Hebei Medical Journal, 2021, 43(14): 2168-2170, 2174. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202114021.htm
    [4]
    何柳, 柯艳, 张珊祥, 等. 重度缺氧缺血性脑病患儿有创通气下全身亚低温治疗干预性护理效果分析[J]. 中华新生儿科杂志, 2020, 35(4): 296-298. doi: 10.3760/cma.j.issn.2096-2932.2020.04.012

    HE L, KE Y, ZHANG S X, et al. Analysis of interventional nursing effect of systemic mild hypothermia on severe hypoxic ischemic encephalopathy with invasive ventilation[J]. : Chinese Journal of Neonatology, 2020, 35(4): 296-298. doi: 10.3760/cma.j.issn.2096-2932.2020.04.012
    [5]
    余清梅, 罗振峰. 综合护理配合亚低温疗法治疗新生儿缺氧缺血性脑病的效果分析[J]. 实用临床医药杂志, 2018, 22(12): 121-123, 127. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL201812035.htm

    YU Q M, LUO Z F. Effect of comprehensive nursing and hypothermia therapy in the treatment of neonatal hypoxia ischemic brain disease[J]. Journal of Clinical Medicine in Practice, 2018, 22(12): 121-123, 127. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL201812035.htm
    [6]
    邵肖梅. 亚低温治疗新生儿缺氧缺血性脑病方案(2011)[J]. 中国循证儿科杂志, 2011, 6(5): 337-339. doi: 10.3969/j.issn.1673-5501.2011.05.005

    SHAO X M. Mild hypothermia for neonatal hypoxic ischemic encephalopathy[J]. Chinese Journal of Evidence-Based Pediatrics, 2011, 6(5): 337-339. doi: 10.3969/j.issn.1673-5501.2011.05.005
    [7]
    尚云, 夏于荣, 郭喜霞, 等. 促红细胞生成素与亚低温治疗在足月新生儿缺氧缺血性脑病中的疗效对比[J]. 河北医学, 2019, 25(2): 292-296. doi: 10.3969/j.issn.1006-6233.2019.02.031

    SHANG Y, XIA Y R, GUO X X, et al. Effectiveness comparison of Erythropoietin and Mild Hypothermia in Full-term Neonates with Hypoxic-ischemic Encephalopathy[J]. Hebei Medicine, 2019, 25(2): 292-296. doi: 10.3969/j.issn.1006-6233.2019.02.031
    [8]
    周玉帆, 甄沁茹, 刘萌. 新生儿缺氧缺血性脑病亚低温治疗短期预后的影响因素[J]. 医药论坛杂志, 2021, 42(22): 117-121. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYX202122031.htm

    ZHOU Y F, ZHEN Q R, LIU M. Short-term prognostic factors of hypoxic-ischemic encephalopathy in neonates treated with mild hypothermia[J]. Journal of Medical Forum, 2021, 42(22): 117-121. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYX202122031.htm
    [9]
    刘翱搏, 李杨. 全身亚低温疗法在新生儿缺氧缺血性脑病治疗中的应用及其护理[J]. 解放军护理杂志, 2017, 34(6): 36-40. https://www.cnki.com.cn/Article/CJFDTOTAL-JFHL201706009.htm

    LIU X B, LI Y. Application and nursing of systemic mild hypothermia in the treatment of neonatal hypoxic ischemic encephalopathy[J]. Nursing Journal of Chinese People's Liberation Army, 2017, 34(6): 36-40. https://www.cnki.com.cn/Article/CJFDTOTAL-JFHL201706009.htm
    [10]
    王俊娟, 董菲. 循证护理在新生儿缺氧缺血性脑病护理中的应用[J]. 河北医药, 2020, 42(09): 1437-1440. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202009039.htm

    WANG J J, DONG F. Application of evidence-based nursing in the nursing of neonatal hypoxic ischemic encephalopathy[J]. Hebei Medical Journal, 2020, 42(09): 1437-1440. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202009039.htm
    [11]
    冯美丽, 宋洁, 赵丽莉. 对接受全身亚低温治疗的新生儿缺氧缺血性脑病患儿进行综合护理的效果探讨[J]. 当代医药论丛, 2019, 17(3): 209-210. https://www.cnki.com.cn/Article/CJFDTOTAL-QYWA201903155.htm

    FENG M L, SONG J, ZHAO L L. Effect of comprehensive nursing on neonates with hypoxic ischemic encephalopathy treated with mild hypothermia[J]. Contemporary Medical Symposium, 2019, 17(3): 209-210. https://www.cnki.com.cn/Article/CJFDTOTAL-QYWA201903155.htm
    [12]
    鞠永娜. 新生儿缺氧缺血性脑病亚低温治疗中预见性临床护理效果观察[J]. 包头医学, 2020, 44(2): 65. https://www.cnki.com.cn/Article/CJFDTOTAL-BTYI202002031.htm

    JU Y N. Observation of predictive clinical nursing effect in mild hypothermia treatment of neonatal hypoxic ischemic encephalopathy[J]. Journal of Baotou Medicine, 2020, 44(2): 65. https://www.cnki.com.cn/Article/CJFDTOTAL-BTYI202002031.htm
    [13]
    王林林. 对进行全身亚低温治疗的新生儿缺氧缺血性脑病患儿实施综合护理的效果探析[J]. 当代医药论丛, 2019, 17(19): 256-257. https://www.cnki.com.cn/Article/CJFDTOTAL-QYWA201919199.htm

    WANG L L. Effect of comprehensive nursing on neonates with hypoxic ischemic encephalopathy treated with mild hypothermia[J]. Contemporary Medical Symposium, 2019, 17(19): 256-257. https://www.cnki.com.cn/Article/CJFDTOTAL-QYWA201919199.htm
    [14]
    陈晓香. 机械通气呼吸机管道湿化模式对呼吸机相关性肺炎的影响分析[J]. 中国社区医师, 2018, 34(2): 14, 16. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYS201802007.htm

    CHEN X X. Analysis of the effect of effect of mechanical ventilation ventilator pipeline wetting mode on ventilator-associated pneumonia[J]. Chinese Community Doctors, 2018, 34(2): 14, 16. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYS201802007.htm
    [15]
    任苗会. 新生儿缺氧缺血性脑病亚低温治疗中预见性临床护理效果研究[J]. 微量元素与健康研究, 2021, 38(4): 23-24. https://www.cnki.com.cn/Article/CJFDTOTAL-WYJK202104012.htm

    REN M H. Predictive clinical nursing effect in mild hypothermia treatment of neonatal hypoxic ischemic encephalopathy[J]. Studies of Trace Elements and Health, 2021, 38(4): 23-24. https://www.cnki.com.cn/Article/CJFDTOTAL-WYJK202104012.htm
    [16]
    于晓晨, 纪文静, 张永辉. 亚低温治疗对重型颅脑损伤患者上消化道出血的影响[J]. 黑龙江医药, 2017, 30(5): 1088-1089. https://www.cnki.com.cn/Article/CJFDTOTAL-HJYY201705070.htm

    YU X C, JI W J, ZHANG Y H. Effects of mild hypothermia on upper gastrointesti-nal bleeding in patients with severe craniocerebral injury[J]. Heilongjiang Medicine Journal, 2017, 30(5): 1088-1089. https://www.cnki.com.cn/Article/CJFDTOTAL-HJYY201705070.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(4)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (245) PDF downloads(4) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return