Volume 21 Issue 6
Jun.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(6): 954-957
WU Juan, ZHOU Lanzhu, SUN Zhe, WU Jun, WANG Wenzhong. Clinical features and treatment analysis of esophageal entrance invasion in hypopharyngeal carcinoma[J]. Chinese Journal of General Practice, 2023, 21(6): 954-957. doi: 10.16766/j.cnki.issn.1674-4152.003023
Citation: WU Juan, ZHOU Lanzhu, SUN Zhe, WU Jun, WANG Wenzhong. Clinical features and treatment analysis of esophageal entrance invasion in hypopharyngeal carcinoma[J]. Chinese Journal of General Practice, 2023, 21(6): 954-957. doi: 10.16766/j.cnki.issn.1674-4152.003023
shu

Clinical features and treatment analysis of esophageal entrance invasion in hypopharyngeal carcinoma

doi: 10.16766/j.cnki.issn.1674-4152.003023

  • Department of Otolaryngology and Head and Neck Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2020A0568

 KJ2020A0590

  • Received Date: 2022-08-12
    Available Online: 2023-08-26
    Abstract
  •   Objective  To analyze the basic clinical characteristics of esophageal entrance invasion in hypopharyngeal carcinoma, summarize the therapeutic effect and select the appropriate comprehensive treatment plan.  Methods  A total of 32 patients with hypopharyngeal squamous cell carcinoma invading the esophageal entrance treated by Otolaryngology Head and Neck Surgery at the First Affiliated Hospital of Bengbu Medical College from January 2014 to January 2017 were retrospectively analyzed. The basic clinical information of patients were collected, postoperative survival was followed up, and the basic clinical characteristics and treatment efficacy of hypopharyngeal cancer invading the esophageal entrance were analyzed.  Results  The 32 patients were all male, aged 44 to 81 (62.7±9.0) years old, including 28 piriform fossa carcinoma, 2 retropharyngeal wall carcinoma and 2 posterior annular carcinoma. Tumor TNM stage: 2 cases of T3N1M0, 5 cases of T3N2M0, 1 case of T3N3M0, 1 case of T4N1M0, 20 cases of T4N2M0, and 3 cases of T4N3M0. The tumor pathology was all squamous cell carcinoma, with pathological grade: 3 patients were highly differentiated, 14 patients were moderately differentiated, and 15 patients were poorly differentiated. The operation was successfully performed in all patients, 25 cases underwent radical neck dissection and 7 cases underwent selective neck dissection. The 3-year overall survival rate was 62.5% (20/32), and the 5-year overall survival rate was 34.4% (11/32). In 24 cases of unreserved laryngeal function, the 3-year survival rate was 66.7% (16/24), and the 5-year survival rate was 37.5% (9/24). There were 8 cases preserved laryngeal function, with a 3-year survival rate of 50.0% (4/8) and a 5-year survival rate of 25.0% (2/8). Among them, 5 cases (62.5%) had complete recovery of laryngeal function (respiratory, vocal, and swallowing protection), and 3 cases (37.5%) had recovery of vocal and swallowing protection.  Conclusion  Hypopharyngeal carcinoma invading esophageal entrance has high malignancy degree and poor prognosis. Preoperative examination should be actively improved, and treatment plans should be selected according to tumor stage and physical condition of patients, with comprehensive treatment based on surgery.

     

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