Volume 21 Issue 6
Jun.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(6): 970-972
JIANG Feng, JIN Chunyuan, WANG Bona, HE Songbin. Correlation analysis of serum β-actin and quantitative EEG indicators in patients with acute cerebral infarction[J]. Chinese Journal of General Practice, 2023, 21(6): 970-972. doi: 10.16766/j.cnki.issn.1674-4152.003027
Citation: JIANG Feng, JIN Chunyuan, WANG Bona, HE Songbin. Correlation analysis of serum β-actin and quantitative EEG indicators in patients with acute cerebral infarction[J]. Chinese Journal of General Practice, 2023, 21(6): 970-972. doi: 10.16766/j.cnki.issn.1674-4152.003027
shu

Correlation analysis of serum β-actin and quantitative EEG indicators in patients with acute cerebral infarction

doi: 10.16766/j.cnki.issn.1674-4152.003027
  • 1.

    Department of EEG Room, Zhoushan Hospital of Zhejiang Province, Zhoushan, Zhejiang 316000, China

Funds:

 2022KY1367

  • Received Date: 2022-11-12
    Available Online: 2023-08-26
    Abstract
  •   Objective  To explore the changes of serum β-actin and quantitative indicators EEG of acute cerebral infarction, and analyses its correlation.  Methods  A total of 60 patients with acute cerebral infarction from June 2021 to June 2022 in Zhoushan Hospital of Zhejiang Province were selected. There were 24 cases in mild group, 24 cases in moderate group and 12 cases in severe group; Another 50 cases of physical examination in the same period in Zhoushan Hospital of Zhejiang Province were selected as the control group. β-actin level measured by enzyme-linked immunosorbent assay. EEG was used to monitor patients ' EEG, and relative power value and power ratio index of each frequency band(DTABR) was calculated.  Results  The β-actin level [(1.83±0.34)μg/L] and DTABR value (7.71±0.43) in the cerebral infarction group were higher than those in the control group [(0.64±0.12)μg/L and 6.24±0.32], t=23.542, 19.991, both P < 0.05. The β-actin level [(2.29±0.41) μg/L] and DTABR value (8.54±0.47) in the severe group were higher than those in the moderate group [(1.79±0.36)μg/L and 7.68±0.42] and mild group [(1.27±0.28) μg/L and 6.63±0.34], all P < 0.05, while the β-actin level and DTABR value in the moderate group were higher than those in the mild group (all P < 0.05). The Pearson analysis showed that the level of β-actin was positively correlated with the DTABR value (r=0.584, P=0.002). Multivariate logistic regression analysis showed that β-actin and DTABR were the influencing factors for patients with cerebral infarction.  Conclusion  Serum β-actin level and DTABR value in patients with acute cerebral infarction significantly increase, which are closely related to the severity of the disease, and the level of β-actin is positively correlated with the value of DTABR.

     

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