Volume 21 Issue 6
Jun.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(6): 1026-1029
WU Dongdong, YU Guoqiang, TENG Jinyan, TAN Zengde, ZHOU Yabin, ZHANG Mingming. Effects of Ziwu Liuzhu auricular points pressing beans on inflammatory cytokines and NT-proBNP levels in patients with chronic heart failure[J]. Chinese Journal of General Practice, 2023, 21(6): 1026-1029. doi: 10.16766/j.cnki.issn.1674-4152.003041
Citation: WU Dongdong, YU Guoqiang, TENG Jinyan, TAN Zengde, ZHOU Yabin, ZHANG Mingming. Effects of Ziwu Liuzhu auricular points pressing beans on inflammatory cytokines and NT-proBNP levels in patients with chronic heart failure[J]. Chinese Journal of General Practice, 2023, 21(6): 1026-1029. doi: 10.16766/j.cnki.issn.1674-4152.003041
shu

Effects of Ziwu Liuzhu auricular points pressing beans on inflammatory cytokines and NT-proBNP levels in patients with chronic heart failure

doi: 10.16766/j.cnki.issn.1674-4152.003041
  • 1.

    Clinical Medicine School, Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang 150040, China

Funds:

 LBH-Z19216

  • Received Date: 2022-07-12
    Available Online: 2023-08-26
    Abstract
  •   Objective  To observe the effect of time-controlled Ziwu Liuzhu auricular points pressing beans on inflammatory cytokines and N-terminal pro-Brain natriuretic peptide (NT-proBNP) levels in patients with chronic heart failure (CHF). To investigate the mechanism of Ziwu Liuzhu auricular points pressing beans and earlobes to improve TCM symptoms, heart function and exercise tolerance in patients with CHF.  Methods  A total of 80 patients with CHF who admitted in the Outpatient Clinic in the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from January 2019 to June 2020 were selected and divided into a control group and an observation group by using the random number table method, with 40 cases in each group (2 cases dropped off in the control group and 1 case dropped off in the observation group). The control group received routine basic treatment, while the observation group was treated by Ziwu Liuzhu auricular points pressing beans on the basis of the control group. Changes in serum left ventricular ejection fraction (LVEF), 6-min walking distance (6MWD), IL-6, hypersensitive C-reactive protein (hs-CRP) and NT-proBNP in both groups were observed before and after treatment. The clinical efficacy and efficacy of TCM symptoms were compared between the two groups.  Results  After treatment, the LVEF and 6MWD in the observation group were significantly improved compared to before treatment (P < 0.05), and the observation group was superior to the control group (P < 0.05); The serum levels of IL-6, hs-CRP, and NT-proBNP in the observation group were significantly reduced compared to before treatment (P < 0.05), and the observation group was superior to the control group (P < 0.05). The total effective rate of active TCM symptoms in the observation group was 92.3% (36/39), which was significantly better than that in the control group [34.2% (13/38), P < 0.05]. The total clinical effective rate of the observation group was 71.8% (28/39), while the control group was 44.7% (17/38), with a statistically significant difference (P < 0.05).  Conclusion  Ziwu Liuzhu auricular points pressing beans may significantly improve the clinical efficacy of CHF patients, improve CHF patients ' TCM symptoms, cardiac function and activity endurance, and reduce serum IL-6, hs-CRP and NT-proBNP levels in CHF patients.

     

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