Volume 21 Issue 7
Jul.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(7): 1172-1174
LI Na, LI Nan, WEI Xueyan, SHI Junran, WANG Jingjun, ZHOU Xiumin, LIU Yanxia. Study on the effect of self-made traditional Chinese medicine formula combined with far infrared therapeutic instrument in the treatment of drug exudation or extravasation in children[J]. Chinese Journal of General Practice, 2023, 21(7): 1172-1174. doi: 10.16766/j.cnki.issn.1674-4152.003077
Citation: LI Na, LI Nan, WEI Xueyan, SHI Junran, WANG Jingjun, ZHOU Xiumin, LIU Yanxia. Study on the effect of self-made traditional Chinese medicine formula combined with far infrared therapeutic instrument in the treatment of drug exudation or extravasation in children[J]. Chinese Journal of General Practice, 2023, 21(7): 1172-1174. doi: 10.16766/j.cnki.issn.1674-4152.003077
shu

Study on the effect of self-made traditional Chinese medicine formula combined with far infrared therapeutic instrument in the treatment of drug exudation or extravasation in children

doi: 10.16766/j.cnki.issn.1674-4152.003077
  • 1.

    Second Department of Pediatrics, Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang, Hebei 050006, China

Funds:

 2020287

  • Received Date: 2023-02-16
    Available Online: 2023-08-28
    Abstract
  •   Objective  To explore the clinical efficacy of self-made traditional Chinese medicine prescription combined with far infrared therapeutic instrument in the treatment of drug exudation in children and its impact on the levels of serum superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in patients.  Methods  A total of 126 children with local drug exudation or extravasation during infusion in the Pediatric and Traditional Chinese Medicine Pediatric Departments of Shijiazhuang Maternal and Child Health Hospital from January 2020 to June 2022 were selected as study subjects, and randomly divided into a control group and an observation group using a random number table method, with 63 patients in each group. The control group was treated with 50% magnesium sulfate wet compress combined with far infrared therapeutic instrument. The children in the observation group were treated with self-made traditional Chinese medicine prescription combined with combined with far infrared therapeutic instrument. The treatment effect was observed and the visual analog scale (VAS) score, skin symptom recovery time, SOD and GSH-Px levels between the two groups were compared.  Results  The observation group had 36 cases of significant effect, 27 cases of effective treatment, and 0 cases of ineffective treatment, while the control group had 22 cases, 28 cases and 13 cases, respectively. The treatment effect in the observation group was better than that in the control group (Z=-3.325, P=0.001). After 24 hours of treatment, the VSA score in the observation group were lower than those in the control group (P < 0.05). The regression time of pain, inflammation, and redness in the observation group was shorter than that in the control group (P < 0.05). After 24 hours of treatment, the levels of SOD and GSH-Px in the observation group were higher than those in the control group (P < 0.05).  Conclusion  Self-made traditional Chinese medicine prescription combined with far infrared therapeutic instrument has good effect on exudation or exudation, and its mechanism may be related to improving serum SOD and GSH-Px.

     

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    • References(30)
  • [1]
    姚勋霞, 张理想, 曹教育, 等. 外周静脉应用血管活性药物致静脉炎危险因素的评估指标体系构建[J]. 护理学报, 2021, 28(12): 65-70. doi: 10.16460/j.issn1008-9969.2021.12.065

    YAO X X, ZHANG L X, CAO J Y, et al. Construction of evaluation index system for risk factors of vasoactive drug-induced phlebitis in patients with cardiovascular diseases[J]. Journal of Nursing, 2021, 28(12): 65-70. doi: 10.16460/j.issn1008-9969.2021.12.065
    [2]
    王军静, 徐秋生, 高晓冉, 等. 丹芍凉血方熏洗结合喜辽妥外用治疗急性期下肢血栓性浅静脉炎的疗效观察[J]. 中国中医急症, 2022, 31(5): 888-891. doi: 10.3969/j.issn.1004-745X.2022.05.037

    WANG J J, XU Q S, GAO X R, et al. Efficacy Observation on danshao liangxue decoction fumigation and washing combined with mucopolysaccharide polysulfate cream topical treatment for acute superficial vein thrombophlebitis of lower extremity[J]. Journal of Emergency in Traditional Chinese Medicine, 2022, 31(5): 888-891. doi: 10.3969/j.issn.1004-745X.2022.05.037
    [3]
    蒋媛媛, 陆海霞, 梁祝额, 等. 儿童静脉输液外渗的预防和护理进展[J]. 医学食疗与健康, 2021, 19(12): 227-228. https://www.cnki.com.cn/Article/CJFDTOTAL-JTHS201812012.htm

    JIANG Y Y, LU H X, LIANG Z E, et al. Progress in prevention and nursing of venous infusion extravasation in children[J]. Medical Dietary Therapy and Health, 2021, 19(12): 227-228. https://www.cnki.com.cn/Article/CJFDTOTAL-JTHS201812012.htm
    [4]
    李艳玲, 刘兰, 赵子晖, 等. 黑芝麻小磨香油对盐酸胺碘酮注射液所致静脉炎的影响[J]. 实用临床医药杂志, 2022, 26(12): 112-114, 124. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202212024.htm

    LI Y L, LIU L, ZHAO Z H, et al. Effects of refined black sesame oil on amiodarone-induced phlebitis[J]. Journal of Clinical Medicine in Practice, 2022, 26(12): 112-114, 124. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202212024.htm
    [5]
    李婵, 刘兰, 徐树彬, 等. 复方黄柏液蜡疗治疗不同分期下肢血栓性静脉炎的疗效及对血清炎症因子的影响[J]. 临床和实验医学杂志, 2022, 21(20): 2180-2184. doi: 10.3969/j.issn.1671-4695.2022.20.015

    LI C, LIU L, XU S B, et al. Efficacy of compound cortex phellodendron solution wax therapy in the treatment of thrombophlebitis of the lower extremities in different stages and its effect on serum inflammatory factors[J]. Journal of Clinical and Experimental Medicine, 2022, 21(20): 2180-2184. doi: 10.3969/j.issn.1671-4695.2022.20.015
    [6]
    赵雨晴, 魏志平, 周迪, 等. 舒肝健脾养血法对寻常型银屑病患者免疫功能、炎症因子的影响[J]. 陕西中医, 2022, 43(1): 69-72. https://www.cnki.com.cn/Article/CJFDTOTAL-SXZY202201017.htm

    ZHAO Y Q, WEI Z P, ZHOU D, et al. The Effect of Shugan Jianpi Yangxue method on immune function and inflammatory factors in patients with psoriasis vulgaris[J]. Shaanxi Journal of Traditional Chinese Medicine, 2022, 43(1): 69-72. https://www.cnki.com.cn/Article/CJFDTOTAL-SXZY202201017.htm
    [7]
    张艳芝. 中药穴位贴敷配合静脉输液治疗小儿肠系膜淋巴结炎的临床观察[J]. 世界最新医学信息文摘, 2019, 19(54): 34, 36. https://www.cnki.com.cn/Article/CJFDTOTAL-WMIA201954018.htm

    ZHANG Y Z. Clinical observation of acupuncture combined with herbal separated moxibustion in treating mesenteric lymphadenitis in children[J]. World Latest Medicine Information, 2019, 19(54): 34, 36. https://www.cnki.com.cn/Article/CJFDTOTAL-WMIA201954018.htm
    [8]
    BRAITHWAITE D, MIGLIORETTI D L, ZHU W W, et al. Family history and breast cancer risk among older women in the breast cancer surveillance consortium cohort[J]. JAMA Intern Med, 2018, 178(4): 494-501. doi: 10.1001/jamainternmed.2017.8642
    [9]
    罗章梅, 鲍金霞. 中药湿敷对化疗性静脉炎治疗作用的临床研究[J]. 四川中医, 2021, 39(2): 73-76. https://www.cnki.com.cn/Article/CJFDTOTAL-SCZY202102025.htm

    LIU Z M, BAO J X. Clinical study on the therapeutic effect of Traditional Chinese Medicine wet compress for chemotherapeutic phlebitis[J]. Journal of Sichuan of Traditional Chinese Medicine, 2021, 39(2): 73-76. https://www.cnki.com.cn/Article/CJFDTOTAL-SCZY202102025.htm
    [10]
    KIRCA N, TUZCU A, GÖZVM S. Breast cancer screening behaviors of first degree relatives of women receiving breast cancer treatment and the affecting factors[J]. Eur J Breast Health, 2018, 14(l): 23-28.
    [11]
    王艳梅, 陆静, 施蓉玲. 上海某二甲医院PICC带管出院患者导管维护知信行现状调查及影响因素分析[J]. 中华现代护理杂志, 2018, 24(14): 1639-1643.

    WANG Y M, LIU J, SHI R L. Knowledge-Attitude-Practice about PICC catheter in patients discharged with PICC of a Shanghai 2A hospital and its influencing factors[J]. Modern Nursing, 2018, 24(14): 1637-1643.
    [12]
    章巧庆, 叶蔚蔚, 张彬娥, 等. 维持性血液透析患者内瘘性静脉炎相关护理因素分析[J]. 浙江临床医学, 2018, 20(2): 359-361.

    ZHANG Q Q, YE W W, ZHANG B E, et al. Analysis of related nursing factors of internal fistula phlebitis in maintenance hemodialysis patients[J]. Zhejiang Clinical Medical Journal, 2018, 20(2): 359-361.
    [13]
    颜征, 安震, 张玥, 等. 联合中药外敷疗法治疗血栓性浅静脉炎有效性的Meta分析[J]. 中国中西医结合外科杂志, 2022, 28(5): 650-654. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZX202205011.htm

    YAN Z, AN Z, ZAHNG Y, et al. Meta-analysis of efficacy of combined external application of Traditional Chinese Medicine in treatment of superficial vein thrombosis[J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 2022, 28(5): 650-654. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZX202205011.htm
    [14]
    刘继松, 宋德恒, 赵刚宏, 等. 新型生物敷料Ⅱ型在二度烧伤创面中的应用[J]. 中华全科医学, 2018, 16(5): 740-743. doi: 10.16766/j.cnki.issn.1674-4152.000201

    LIU J S, SONG D H, ZHAO G H, et al. Application of new biological dressing type Ⅱ in the second degree burn wounds[J]. Chinese Journal of General Practice, 2018, 16(5): 740-743. doi: 10.16766/j.cnki.issn.1674-4152.000201
    [15]
    罗春绸, 蔡惠贞, 姚秀娥, 等. 地塞米松溶液封管预防经外周静脉导管输注甘露醇所致静脉炎的应用研究[J]. 解放军护理杂志, 2021, 38(2): 22-25. https://www.cnki.com.cn/Article/CJFDTOTAL-JFHL202102006.htm

    LUO C C, CAI H Z, YAO X E, et al. Application research o f dexamethasone solution sealing in preventing phlebitis caused by mannitol infusion through peripheral indwelling needle[J]. Nursing Journal of Chinese People's Liberation Army, 2021, 38(2): 22-25. https://www.cnki.com.cn/Article/CJFDTOTAL-JFHL202102006.htm
    [16]
    BRAVI F, DECARLI A, RUSSO A G. Risk factors for breast cancer in a cohort of mammographic screening program: a nested case-control study within the FRiCaM study[J]. Cancer Med, 2018, 7(5): 2145-2152.
    [17]
    王霞, 桑飞, 郭鑫, 等. 赤芍总苷对慢性盆腔炎大鼠炎症抑制作用及NF-κB通路的调节作用研究[J]. 河北医药, 2022, 44(6): 805-809. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202206001.htm

    WANG X, SANG F, GUO X, et al. Study on the inhibitory effects of total glucosides of paeony on inflammation and the regulation effects on NF-κB pathway in rats with chronic pelvic inflammation[J]. Hebei Medical Journal, 2022, 44(6): 805-809. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202206001.htm
    [18]
    徐静, 钟良, 吴佳珍, 等. 杨志波运用中药内服外敷治疗玫瑰痤疮经验[J]. 河南中医, 2022, 42(5): 693-697. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZY202205011.htm

    XU J, ZHONG L, WU J Z, et al. Yang Zhi-bo's Experience of Treating Rose Acne with Oral Administration of TCM and External Application of TCM[J]. Henan Traditional Chinese Medicine, 2022, 42(5): 693-697. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZY202205011.htm
    [19]
    万红兵, 程金荣. 丹参多酚酸盐联合氯吡格雷治疗冠心病的疗效及对患者hs-CRP、血管内皮功能、血液流变学的影响[J]. 中国现代医生, 2018, 56(35): 40-42, 46. https://www.cnki.com.cn/Article/CJFDTOTAL-ZDYS201835010.htm

    WANG H B, CHENG J R. Therapeutic effect of salvianolate combined with clopidogrel on coronary heart disease and its effects on hs-CRP, vascular endothelial function and hemorheology[J]. Modern Chinese Doctor, 2018, 56(35): 40-42, 46. https://www.cnki.com.cn/Article/CJFDTOTAL-ZDYS201835010.htm
    [20]
    李佳晌, 赵子樟, 缪晓冬, 等. 基于网络药理学-分子对接研究乳香-没药配伍改善类风湿性关节炎的作用机制[J]. 中国中药杂志, 2021, 46(10): 2371-2379. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZY202110001.htm

    LI J S, ZHAO Z Z, MIAO X D, et al. Mechanism of Olibanum-Myrrha in treatment of rheumatoid arthritis based on network pharmacology and molecular docking[J]. China Journal of Chinese Materia Medica, 2021, 46(10): 2371-2379. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZY202110001.htm
    [21]
    赵子樟, 李佳晌, 宿树兰, 等. 基于网络药理学及细胞实验的乳香-没药功效成分抗炎机制研究[J]. 中国中药杂志, 2021, 46(21): 5674-5682. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZY202121026.htm

    ZAHO Z Z, LI J S, SU S L, et al. Anti-inflammatory mechanism of active components in Olibanum and Myrrha based on network pharmacology and cell experiments[J]. China Journal of Chinese Materia Medica, 2021, 46(21): 5674-5682. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZY202121026.htm
    [22]
    李世杰, 马立琼, 熊贤梅, 等. 三七总皂苷对富血小板血浆促进兔骨缺损愈合的影响[J]. 中国组织工程研究, 2022, 26(14): 2155-2160. https://www.cnki.com.cn/Article/CJFDTOTAL-XDKF202214008.htm

    LI S J, MA L Q, XIONG X M, et al. Effect of panax notoginseng saponins on platelet-rich plasma promoting bone defect healing in rabbits[J]. Chinese Journal of Tissue Engineering Research, 2022, 26(14): 2155-2160. https://www.cnki.com.cn/Article/CJFDTOTAL-XDKF202214008.htm
    [23]
    陈燕珠. 月经不调患者应用逍遥丸联合四物汤治疗的效果及安全性分析[J]. 中外医学研究, 2023, 21(3): 53-57. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY202303013.htm

    CHENG Y Z. Effect and safety analysis of Xiaoyao Pills combined with Siwu Decoction in the treatment of patients with irregular menstruation[J]. Chinese and Foreign Medical Research, 2023, 21(3): 53-57. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY202303013.htm
    [24]
    李丰涛, 刘丹丹. 当归益气方联合苯磺酸左旋氨氯地平片治疗阴阳两虚型原发性高血压的临床疗效及对中医证候积分和血液流变学的影响[J]. 中医研究, 2021, 34(11): 30-33. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYJ202111010.htm

    LI F T, LIU D D. Clinical efficacy of Danggui Yiqi Recipe combined with levo amlodipine benzenesulfonate tablet in the treatment of essential hypertension of yin yang deficiency type and its influence on TCM syndrome integral and hemorheology[J]. Traditional Chinese Medicinal Research, 2021, 34(11): 30-33. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYJ202111010.htm
    [25]
    葛亚梅, 陈俊. 血塞通注射液联合羟苯磺酸钙胶囊治疗非增殖期糖尿病视网膜病变的疗效及对血清炎性因子水平的影响[J]. 湖北中医杂志, 2023, 45(1): 6-9. https://www.cnki.com.cn/Article/CJFDTOTAL-HBZZ202301002.htm

    GE Y M, CHEN J. Efficacy of Xuesaitong Injection combined with calcium dobesilate capsules in treatment of diabetic retinopathy and its effect on serum inflammatory factor levels[J]. Hubei Journal of Traditional Chinese Medicine, 2023, 45(1): 6-9. https://www.cnki.com.cn/Article/CJFDTOTAL-HBZZ202301002.htm
    [26]
    张桐, 伊桐凝. 基于系统药理学研究黄芪-熟地黄治疗糖尿病肾病的作用机制[J]. 中医临床研究, 2022, 14(34): 7-12. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYLY202234002.htm

    ZAHNG T, YI T N. The action mechanism of Huangqi-Shu Dihuang medicine pair on diabetic nephropathy based on system pharmacology[J]. Clinical Journal Of Chinese Medicine, 2022, 14(34): 7-12. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYLY202234002.htm
    [27]
    陈剑平, 李常慧, 黄诗莹, 等. 基于成分表征和网络药理学研究黄芪丹参煎液治疗急性肾损伤的质量标志物[J]. 中国药师, 2022, 25(12): 2079-2086. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYSG202212004.htm

    CHEN J P, LI C H, HUANG S Y, et al. Study on the Q-Markers for Huangqi-Danshen Decoction in the treatment of acute kidney injury based on constituents characterization and network pharmacology[J]. China Pharmacist, 2022, 25(12): 2079-2086. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYSG202212004.htm
    [28]
    姜春晖, 孙旭东, 唐燕, 等. 姜黄素通过Nrf2信号通路对H2O2诱导奶牛乳腺上皮细胞氧化应激的缓解[J]. 中国农业科学, 2021, 54(8): 1787-1794. https://www.cnki.com.cn/Article/CJFDTOTAL-ZNYK202108017.htm

    JIANG C H, SUN X D, TANG Y, et al. Curcumin alleviates H2O2-induced oxidative stress in bovine mammary epithelial cells via the Nrf2 signaling pathway[J]. Scientia Agricultura Sinica, 2021, 54(8): 1787-1794. https://www.cnki.com.cn/Article/CJFDTOTAL-ZNYK202108017.htm
    [29]
    张斌, 窦榆生. 内服姜黄素联合外敷808药膏治疗膝骨性关节炎临床疗效观察[J]. 辽宁中医药大学学报, 2017, 19(7): 151-154. https://www.cnki.com.cn/Article/CJFDTOTAL-LZXB201707044.htm

    ZAHNG B, DOU Y S. Clinical effect observation of oral curcumin combined with 808 ointment external application for the treatment of knee osteoarthritis[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2017, 19(7): 151-154. https://www.cnki.com.cn/Article/CJFDTOTAL-LZXB201707044.htm
    [30]
    肖凤, 汪超兰, 陈竞纬. 基于中医传承辅助平台探讨赵笑东主任治疗高脂血症用药规律[J]. 浙江中医药大学学报, 2022, 46(4): 412-420. https://www.cnki.com.cn/Article/CJFDTOTAL-BHON202204011.htm

    XIAO F, WANG C L, CHENG J W. Explore the medication rule of director ZHAO Xiaodong in treating hyperlipidemia based on the traditional chinese medicine inheritance support system platform[J]. Journal of Zhejiang Chinese Medical University, 2022, 46(4): 412-420. https://www.cnki.com.cn/Article/CJFDTOTAL-BHON202204011.htm
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