Volume 21 Issue 7
Jul.  2023
Turn off MathJax
Article Contents
ZHANG Changying, CHEN Xueli, FENG Yunren, SHI Liang, HE Yuan. Study on the correlation between micronutrient intake during pregnancy and glycemic control outcomes in patients with gestational diabetes[J]. Chinese Journal of General Practice, 2023, 21(7): 1175-1178. doi: 10.16766/j.cnki.issn.1674-4152.003078
Citation: ZHANG Changying, CHEN Xueli, FENG Yunren, SHI Liang, HE Yuan. Study on the correlation between micronutrient intake during pregnancy and glycemic control outcomes in patients with gestational diabetes[J]. Chinese Journal of General Practice, 2023, 21(7): 1175-1178. doi: 10.16766/j.cnki.issn.1674-4152.003078

Study on the correlation between micronutrient intake during pregnancy and glycemic control outcomes in patients with gestational diabetes

doi: 10.16766/j.cnki.issn.1674-4152.003078
Funds:

 20191IX007

  • Received Date: 2023-03-13
    Available Online: 2023-08-28
  •   Objective  To analyze the correlation between micronutrients intake during pregnancy and the effect of blood glucose control in patients with gestational diabetes (GDM), and to provide a basis for clinical supplementation of micronutrients.  Methods  From May 2020 to January 2023, 100 GDM patients who underwent regular prenatal examinations at Xinchang People ' s Hospital and 100 pregnant women with normal blood glucose levels during the same period of prenatal examination were selected as the GDM group and the control group for the study (all were 27 to 35 weeks of gestation). Basic information and dietary intake status of the study subjects were obtained through questionnaire surveys and 24-hour dietary review methods. Binary logistic regression analysis was used to investigate the effect of micronutrient intake on blood glucose control in GDM pregnant women.  Results  Compared with the control group, the total dietary energy, protein, and fat intake of the GDM group were (2 217.65±156.09) kcal, (97.24±11.42) g, and (66.23±7.83) g, respectively, which were higher than those in the control group [(2 163.44±113.24) kcal, (86.43±9.82) g, (61.77±6.33) g, all P < 0.05]; Binary logistic regression showed that high protein, high fat and low carbohydrate energy supply ratio were risk factors for blood glucose control in GDM pregnant women (OR=2.462, 2.533, 2.126, P < 0.05); Vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin D, vitamin E, zinc, iron, copper, and selenium were protective factors for glycemic control in pregnant women with GDM (OR=0.451, 0.237, 0.184, 0.760, 0.228, 0.081, 0.871, 0.311, 0.073, 0.105, P < 0.05).  Conclusion  The diet structure of GDM pregnant women is unreasonable, the intake of protein and fat is too high, and the intake of carbohydrate is too low. Increased micronutrient intake is associated with better control of blood glucose in GDM pregnant women. clinical emphasis should be placed on micronutrient supplementation to reduce the incidence of gestational diabetes.

     

  • loading
  • [1]
    邹素珍, 叶琼, 吴淋淋, 等. 个性化营养支持对妊娠期糖尿病患者血糖和并发症的影响[J]. 中华全科医学, 2023, 21(3): 438-441. doi: 10.16766/j.cnki.issn.1674-4152.002902

    ZOU S Z, YE Q, WU L L, et al. Evaluation of the efficacy of individualized nutritional guidance on blood glucose and complications in patients with gestational diabetes mellitus[J]. Chinese Journal of General Practice, 2023, 21(3): 438-441. doi: 10.16766/j.cnki.issn.1674-4152.002902
    [2]
    李莉, 程芳, 李友生, 等. 武汉市新洲区妊娠早期妇女维生素D营养状况及相关因素分析[J]. 实用预防医学, 2021, 28(8): 981-983. doi: 10.3969/j.issn.1006-3110.2021.08.022

    LI L, CHENG F, LI Y S, et al. Nutritional status of vitamin D and its related factors among pregnant women in the first trimester in Xinzhou District of Wuhan City[J]. Practical Preventive Medicine, 2021, 28(8): 981-983. doi: 10.3969/j.issn.1006-3110.2021.08.022
    [3]
    SANTANDER BALLESTÍN S, GIMÉNEZ CAMPOS M I, BALLESTÍN BALLESTÍN J, et al. Is supplementation with micronutrients still necessary during pregnancy? A review[J]. Nutrients, 2021, 13(9): 3134. doi: 10.3390/nu13093134
    [4]
    MOUSA A, NAQASH A, LIM S. Macronutrient and micronutrient intake during pregnancy: an overview of recent evidence[J]. Nutrients, 2019, 11(2): 443. doi: 10.3390/nu11020443
    [5]
    梁丽萍, 傅育文, 郑聪霞. 妊娠期糖尿病患者孕前体质指数和血糖水平与膳食营养摄入的相关性[J]. 中国妇幼保健, 2021, 36(3): 540-542. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB202103017.htm

    LIANG L P, FU Y W, ZHENG C X. Association of pre-pregnancy body mass index and blood glucose levels with dietary nutrient intake in patients with gestational diabetes mellitus[J]. Maternal and Child Health Care of China, 2021, 36(3): 540-542. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB202103017.htm
    [6]
    刘宗明, 廖勇敢, 李秀楼. 妊娠期糖尿病孕妇膳食脂肪摄入与血脂及糖尿病发病相关性分析[J]. 中国妇幼保健, 2018, 33(19): 4352-4355. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201819010.htm

    LIU Z M, LIAO Y G, LI X L. Analysis on the correlation between dietary fat intake and blood lipid and occurrence of diabetes mellitus in pregnant women with gestational diabetes mellitus[J]. Maternal and Child Health Care of China, 2018, 33(19): 4352-4355. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201819010.htm
    [7]
    《中国食物成分表》标准版第6版第一二册出版[J]. 营养学报, 2019, 41(5): 426.

    Chinese food Composition Table, 6th Edition, Volume 1 and 2[J]. Acta Nutrimenta Sinica, 2019, 41(5): 426.
    [8]
    杨振宇. 膳食营养干预预防妊娠期糖尿病[J]. 中华预防医学杂志, 2018, 52(1): 101-106. doi: 10.3760/cma.j.issn.0253-9624.2018.01.020

    YANG Z Y. Diet and nutrition interventions prevent gestational diabetes mellitus[J]. Chinese Journal of Preventive Medicine, 2018, 52(1): 101-106. doi: 10.3760/cma.j.issn.0253-9624.2018.01.020
    [9]
    JAMILIAN M, MIRHOSSEINI N, ESLAHI M, et al. The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes[J]. BMC Pregnancy Childbirth, 2019, 19(1): 107. doi: 10.1186/s12884-019-2258-y
    [10]
    DAI C C, FEI Y M, LI J M, et al. A novel review of homocysteine and pregnancy complications[J]. Biomed Res Int, 2021. DOI: 10.1155/2021/6652231.
    [11]
    汪竟成, 赵赟, 李鑫. 合肥市3860例妊娠中、晚期孕妇全血微量元素检测结果分析[J]. 生殖医学杂志, 2020, 29(6): 770-774. doi: 10.3969/j.issn.1004-3845.2020.06.011

    WANG J C, ZHAO Y, LI X. Analysis of whole blood microelements content in 3860 pregnant women with second or third trimester in Hefei city[J]. Journal of Reproductive Medicine, 2020, 29(6): 770-774. doi: 10.3969/j.issn.1004-3845.2020.06.011
    [12]
    古丽柯孜·艾力, 卡米拉·吐尔逊江, 吐尔逊江·买买提明, 等. 喀什市480例孕期妇女膳食营养与血清维生素D、钙营养状况分析[J]. 营养学报, 2021, 43(3): 307-309. doi: 10.3969/j.issn.0512-7955.2021.03.019

    Gulikezi AILI, Kamila TUERXUNJIANG, Tuerxunjiang-MAIMAITIMING, et al. Analysis of dietary intakes, serum vitamin D and calcium status of 480 pregnant women in Kashi City[J]. Acta Nutrimenta Sinica, 2021, 43(3): 307-309. doi: 10.3969/j.issn.0512-7955.2021.03.019
    [13]
    陈俊, 刘玉环, 王莹, 等. 医学营养治疗在妊娠期糖尿病中的临床应用[J]. 第二军医大学学报, 2020, 41(12): 1375-1380. https://www.cnki.com.cn/Article/CJFDTOTAL-DEJD202012011.htm

    CHEN J, LIU Y H, WANG Y, et al. Clinical application of medical nutrition treatment for gestational diabetes mellitus[J]. Academic Journal of Second Military Medical University, 2020, 41(12): 1375-1380. https://www.cnki.com.cn/Article/CJFDTOTAL-DEJD202012011.htm
    [14]
    陈莲花. 孕妇妊娠糖尿病的发病状况及与血清营养素水平的相关性研究[J]. 中国药物与临床, 2020, 20(7): 1143-1145. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC202007042.htm

    CHEN L H. Prevalence of gestational diabetes mellitus and its correlation with serum nutrient levels in pregnant women[J]. Chinese Remedies & Clinics, 2020, 20(7): 1143-1145. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC202007042.htm
    [15]
    陈典玲, 李晓红. 孕妇妊娠糖尿病发病状况及其与血清中营养素含量关系探讨[J]. 山西医药杂志, 2019, 48(9): 1063-1066. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYY201909023.htm

    CHEN D L, LI X H. Prevalence of gestational diabetes mellitus and its relationship with serum nutrient levels in pregnant women[J]. Shanxi Medical Journal, 2019, 48(9): 1063-1066. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYY201909023.htm
    [16]
    MANSUR J L, OLIVERI B, GIACOIA E, et al. Vitamin D: before, during and after pregnancy: effect on neonates and children[J]. Nutrients, 2022, 14(9): 1900.
    [17]
    王娜, 邓泽群, 丁焱, 等. 孕期膳食模式对妊娠期糖尿病发生风险的影响[J]. 中华糖尿病杂志, 2021, 13(9): 865-871.

    WANG N, DENG Z Q, DING Y, et al. Effect of dietary patterns during pregnancy on the risk of developing gestational diabetes mellitus[J]. Chinese Journal Of Diabetes Mellitus, 2021, 13(9): 865-871.
    [18]
    CHEN X T, ZHANG Y, CHEN H Y, et al. Association of maternal folate and vitamin B12 in early pregnancy with gestational diabetes mellitus: a prospective cohort study[J]. Diabetes Care, 2021, 44(1): 217-223.
    [19]
    郭洪萍, 赵艾, 薛勇, 等. 孕期营养素摄入与妊娠期糖尿病孕妇血糖控制效果的相关性研究[J]. 北京大学学报(医学版), 2021, 53(3): 467-472. https://www.cnki.com.cn/Article/CJFDTOTAL-BYDB202103005.htm

    GUO H P, ZHAO A, XUE Y, et al. Relationship between nutrients intake during pregnancy and the glycemic control effect in pregnant women with gestational diabetes mellitus[J]. Journal of Peking University (Health Sciences), 2021, 53(3): 467-472. https://www.cnki.com.cn/Article/CJFDTOTAL-BYDB202103005.htm
    [20]
    FERNANDO M, ELLERY S J, MARQUINA C, et al. Vitamin D-binding protein in pregnancy and reproductive health[J]. Nutrients, 2020, 12(5): 1489.
    [21]
    陈洁芬, 叶碧玉, 卢小颜. 妊娠期糖尿病孕妇膳食摄入与营养水平特征的研究[J]. 护理实践与研究, 2019, 16(6): 75-77. https://www.cnki.com.cn/Article/CJFDTOTAL-HLSJ201906033.htm

    CHEN J F, YE B Y, LU X Y. Dietary intake and nutritional status of pregnant women with gestational diabetes mellitus[J]. Nursing Practice and Research, 2019, 16(6): 75-77. https://www.cnki.com.cn/Article/CJFDTOTAL-HLSJ201906033.htm
    [22]
    雷金菊, 洪新如, 刘超斌. 孕期锌缺乏与胎儿心脏畸形的关系[J]. 福建医科大学学报, 2021, 55(2): 170-174. https://www.cnki.com.cn/Article/CJFDTOTAL-FJYD202102023.htm

    LEI J J, HONG X R, LIU C B. Maternal zinc deficiency during pregnancy and fetal heart malformations[J]. Journal of Fujian Medical University, 2021, 55(2): 170-174. https://www.cnki.com.cn/Article/CJFDTOTAL-FJYD202102023.htm
    [23]
    陈邓周, 王嘉琪, 周鹤, 等. 广州孕妇孕期硒暴露水平与孕晚期胎儿头围的关系[J]. 环境与职业医学, 2021, 38(4): 361-367. https://www.cnki.com.cn/Article/CJFDTOTAL-LDYX202104008.htm

    CHEN D Z, WANG J Q, ZHOU H, et al. Associations between selenium exposure level during pregnancy and fetal head circumference in third trimester of pregnancy[J]. Journal of Environmental and Occupational Medicine, 2021, 38(4): 361-367. https://www.cnki.com.cn/Article/CJFDTOTAL-LDYX202104008.htm
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(4)

    Article Metrics

    Article views (267) PDF downloads(7) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return