Volume 21 Issue 8
Aug.  2023
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LIANG Shunda, FANG Fang, DING Zhiying, LI Xingxing, HE Miao, HUANG Jialin, ZHANG Hong. Analysis of the influence factors of recovery of spontaneous circulation in in-hospital cardiac arrest patients[J]. Chinese Journal of General Practice, 2023, 21(8): 1299-1303. doi: 10.16766/j.cnki.issn.1674-4152.003107
Citation: LIANG Shunda, FANG Fang, DING Zhiying, LI Xingxing, HE Miao, HUANG Jialin, ZHANG Hong. Analysis of the influence factors of recovery of spontaneous circulation in in-hospital cardiac arrest patients[J]. Chinese Journal of General Practice, 2023, 21(8): 1299-1303. doi: 10.16766/j.cnki.issn.1674-4152.003107

Analysis of the influence factors of recovery of spontaneous circulation in in-hospital cardiac arrest patients

doi: 10.16766/j.cnki.issn.1674-4152.003107
Funds:

 2020WR02003

  • Received Date: 2022-11-15
    Available Online: 2023-09-13
  •   Objective  To investigate the factors affecting the return of spontaneous circulation (ROSC) after cardiopulmonary resuscitation in patients with in-hospital cardiac arrest (IHCA) in order to improve the success rate of resuscitation.  Methods  Data of 423 IHCA patients admitted to the Emergency Department, Intensive Care Medicine Department, Respiratory Medicine Department and other departments of the First Affiliated Hospital of Anhui Medical University from November 2019 to November 2020 were retrospectively analyzed. They were divided into ROSC group (109 cases) and ineffective resuscitation group (314 cases) according to whether spontaneous circulation was restored. The influencing factors of ROSC in patients with IHCA were analyzed by univariate analysis. Then, the factors with P < 0.05 in the univariate analysis were included in the binary unconditional logistic regression analysis.  Results  Univariate analysis showed that compared with the non-resuscitation group, the ROSC group included long-term residence (urban/rural), occurrence season of cardiac arrest, ECG manifestations of early repolarization syndrome, history of severe trauma, history of malignancy, first in-hospital department, ICU admission during the course of disease, in-hospital department of cardiac arrest, first detection of heart rhythm, whether endotracheal intubation was performed during cardiopulmonary resuscitation, whether defibrillation was performed, duration of cardiopulmonary resuscitation, whether to use epinephrine, the application of epinephrine dose and other factors, all had statistical significance (P < 0.05). Logistic regression analysis showed that ICU admission (P < 0.001), airway opening (P=0.007), duration of cardiopulmonary resuscitation (P < 0.001) and total epinephrine dose (P < 0.001) were independent factors influencing ROSC in patients with IHCA.  Conclusion  ICU admission, airway opening before cardiac arrest, duration of cardiopulmonary resuscitation, and total epinephrine dose can affect ROSC in patients with IHCA.

     

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