Volume 21 Issue 8
Aug.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(8): 1304-1307
GAO Xiaoman, HE Jianle, XU Xihai, CHEN Yiqing, XIAO Rong, DENG Datong. Analysis of serum 25-hydroxyvitamin D levels and related factors in a population of 4 311 physical examinations in a tertiary hospital in Hefei[J]. Chinese Journal of General Practice, 2023, 21(8): 1304-1307. doi: 10.16766/j.cnki.issn.1674-4152.003108
Citation: GAO Xiaoman, HE Jianle, XU Xihai, CHEN Yiqing, XIAO Rong, DENG Datong. Analysis of serum 25-hydroxyvitamin D levels and related factors in a population of 4 311 physical examinations in a tertiary hospital in Hefei[J]. Chinese Journal of General Practice, 2023, 21(8): 1304-1307. doi: 10.16766/j.cnki.issn.1674-4152.003108
shu

Analysis of serum 25-hydroxyvitamin D levels and related factors in a population of 4 311 physical examinations in a tertiary hospital in Hefei

doi: 10.16766/j.cnki.issn.1674-4152.003108
  • 1.

    Department of General Practice, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

Funds:

 2208085QH242

  • Received Date: 2022-10-12
    Available Online: 2023-09-13
    Abstract
  •   Objective  To study the relationship between serum 25-hydroxyvitamin D [25(OH)D] concentration and season, gender and age using data from the physical examination centre of the First Affiliated Hospital of Anhui Medical University, and to provide a reference for rational clinical vitamin D supplementation.  Methods  Data of 4 311 subjects (> 20 years old) who underwent physical examination from April 2017 to June 2022 (The data of April, May, June 2020 were missing) were selected. Spearman ' s rank correlation coefficient was used to analyze the correlation between monthly average serum 25(OH)D concentration and monthly average temperature, sunshine duration and UV intensity. The detection rates of 25(OH)D sufficiency [25(OH)D ≥75 nmol/L], 25(OH)D insufficiency [50 nmol/L ≤ 25(OH)D < 75 nmol/L] and 25(OH)D deficiency [25(OH)D < 50 nmol/L] were calculated.  Results  The mean serum 25(OH)D level was 59.7 nmol/L and the overall 25(OH)D sufficiency rate was 22.5%, insufficiency rate was 38.6% and deficiency rate was 38.9%. The median serum 25(OH)D concentration in women was lower than that in men. The serum 25(OH)D concentration showed a seasonal variation over the 5-year period and the difference was statistically significant (P < 0.05). Median 25(OH)D concentrations were lower in winter and spring than that in summer and autumn; mean 25(OH)D concentrations and sufficiency rates were higher in people over 60 years of age than in the other two age groups.  Conclusions  Serum 25(OH)D concentrations in the physical examination population are statistically significant in relation to seasonal changes, gender and age. Vitamin D should be supplemented according to different seasons and age groups to prevent osteoporosis, pathological fractures and other diseases.

     

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