Clinical diagnosis and treatment of renal oncocytoma

WANG Shaochen; XUE Sheng; HUANG Xiaoyu; ZHANG Guangyu; ZHOU Wensheng

doi:10.16766/j.cnki.issn.1674-4152.003112

Volume 21 Issue 8

Aug. 2023

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Article Navigation > Chinese Journal of General Practice > 2023 > 21(8): 1319-1321

WANG Shaochen, XUE Sheng, HUANG Xiaoyu, ZHANG Guangyu, ZHOU Wensheng. Clinical diagnosis and treatment of renal oncocytoma[J]. Chinese Journal of General Practice, 2023, 21(8): 1319-1321. doi: 10.16766/j.cnki.issn.1674-4152.003112

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WANG Shaochen, XUE Sheng, HUANG Xiaoyu, ZHANG Guangyu, ZHOU Wensheng. Clinical diagnosis and treatment of renal oncocytoma[J]. Chinese Journal of General Practice, 2023, 21(8): 1319-1321. doi: 10.16766/j.cnki.issn.1674-4152.003112

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Clinical diagnosis and treatment of renal oncocytoma

doi: 10.16766/j.cnki.issn.1674-4152.003112

Department of Urology, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

KJ2020A0557

2020H213

gxygZD2021117

Received Date: 2022-12-28
Available Online: 2023-09-13

Abstract

Abstract

Objective To improve the diagnose and treatment of renal eosinophilic adenoma, to summarize the clinical characteristics of renal eosinophilic adenoma and study the use of auxiliary examination methods to improve the diagnosis and treatment rate of renal eosinophilic adenoma. Methods Retrospective analysis of the clinical data of 31 patients with renal eosinophilic adenoma who were treated in the Department of Urology, the First Affiliated Hospital of Bengbu Medical College from June 2009 to December 2021, including clinical symptoms, auxiliary examinations, imaging data, treatment methods, pathological examinations and follow-up results. Results Thrity-one patients accounted for 2.35% (31/1 321) of kidney tumor patients during the same period. Twenty patients were admitted to the hospital due to renal space occupancy on physical examination, while the remaining 7 patients showed lumbar discomfort, 2 patients showed intermittent gross hematuria, and 2 patients developed fever. The CT values of renal malignancy and renal oncocytoma in plain scan, cortical phase, renal pelvis phase, relative cortical phase and relative renal pelvis phase were statistically different (all P < 0.05). Seven auxiliary examination reports were considered as renal eosinophilic adenoma. Twelve patients underwent nephron-sparing surgery and 19 patients underwent radical nephrectomy for renal cell carcinoma. After surgery, all patients were diagnosed with renal eosinophilic adenoma by pathological examination, and immunohistochemical analysis showed high expression of EMA, E-cadherin, CD117. A total of 31 cases were followed up, and 21 cases had a good prognosis. All patients survived, with a maximum survival time of more than 12 years. Four patients died from non-tumor or other tumor-related causes, and 6 patients were lost to follow-up. Conclusion It is important to confirm the preoperative diagnosis of eosinophilic adenoma using changes in CT values, laboratory examination, puncture biopsies and immunohistochemical results. In treatment, it is recommended to reserve nephron according to the type and size of the tumor. The prognosis of this disease is good, but it still needs active follow-up.
- Renal tumor,
- Oncocytoma,
- Diagnosis,
- CT value,
- Immunohistochemistry,
- Preserve nephron

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References

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Clinical diagnosis and treatment of renal oncocytoma

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