Volume 21 Issue 8
Aug.  2023
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(8): 1326-1328
ZHOU Sen, JIN Xiaowei, ZHANG Guifan, JIANG Yi. Analysis of risk factors of cognitive dysfunction after senile vertebral compression fracture surgery[J]. Chinese Journal of General Practice, 2023, 21(8): 1326-1328. doi: 10.16766/j.cnki.issn.1674-4152.003114
Citation: ZHOU Sen, JIN Xiaowei, ZHANG Guifan, JIANG Yi. Analysis of risk factors of cognitive dysfunction after senile vertebral compression fracture surgery[J]. Chinese Journal of General Practice, 2023, 21(8): 1326-1328. doi: 10.16766/j.cnki.issn.1674-4152.003114
shu

Analysis of risk factors of cognitive dysfunction after senile vertebral compression fracture surgery

doi: 10.16766/j.cnki.issn.1674-4152.003114

  • Department of Anesthesiology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, Zhejiang 325000, China

Funds:

 2023KY1160

  • Received Date: 2023-04-24
    Available Online: 2023-09-13
    Abstract
  •   Objective  To analyze the influencing factors of postoperative cognitive dysfunction (POCD) in elderly patients with vertebral compression fractures, and to provide a reference for clinical prevention strategies.  Methods  A total of 167 elderly patients with osteoporotic vertebral compression fractures, who underwent surgical treatment at Wenzhou Integrated Traditional Chinese and Western Medicine Hospital from January 2018 to December 2022 were selected. The clinical data of the patients were collected. Univariate and multivariate logistic regression analysis were used to investigate the risk factors for postoperative cognitive dysfunction in elderly patients with vertebral compression fractures.  Results  Among 167 patients, 39 patients developed postoperative cognitive dysfunction, with an incidence of 23.35%. Univariate analysis showed that there were significant differences in age, history of alcohol consumption, postoperative infection, perioperative analgesia, postoperative complications, type of anesthesia, operation time, intraoperative mean frontal lobe oxygen saturation, and preoperative anxiety score between patients with and without postoperative cognitive dysfunction (all P < 0.05). Logistic regression analysis showed that age≥65 years (OR=3.347, P=0.007), postoperative analgesia (OR=2.286, P=0.043), general anesthesia (OR=3.920, P=0.005), operation time ≥120 min (OR=3.418, P < 0.001) were the independent risk factors for postoperative cognitive dysfunction.  Conclusion  Older age, postoperative analgesia, general anesthesia and longer operation time are risk factors for postoperative cognitive dysfunction in elderly patients with osteoporotic vertebral compression fractures. Targeted early clinical intervention can be used to prevent and treat postoperative cognitive dysfunction in elderly patients.

     

    • FullText(HTML)
  • loading
    • References(16)
  • [1]
    胡睿, 刘志贵. 老年患者骨科手术术后认知功能障碍防治的研究进展[J]. 广西医学, 2020, 42(19): 2579-2581. https://www.cnki.com.cn/Article/CJFDTOTAL-GYYX202019028.htm

    HU R, LIU Z G. Advances in prevention and treatment of postoperative cognitive dysfunction in elderly patients undergoing orthopedic surgery[J]. Guangxi Medical Journal, 2020, 42(19): 2579-2581. https://www.cnki.com.cn/Article/CJFDTOTAL-GYYX202019028.htm
    [2]
    刘小雷, 张锦飙, 孙中仪, 等. 经皮椎体强化术的手术时机对老年骨质疏松性椎体压缩性骨折治疗效果的影响[J]. 脊柱外科杂志, 2023, 21(1): 7-12. https://www.cnki.com.cn/Article/CJFDTOTAL-JZWK202301002.htm

    LIU X L, ZHANG J B, SUN Z Y, et al. Effects of operation timing of percutaneous vertebral augmentation surgery on treatment of osteoporotic vertebral compression fractures in elderly[J]. Journal of Spinal Surgery, 2023, 21(1): 7-12. https://www.cnki.com.cn/Article/CJFDTOTAL-JZWK202301002.htm
    [3]
    陈远辉, 万海方, 张一肖. 术中脑氧饱和度干预对老年脊柱结核手术患者术后谵妄的影响[J]. 中华全科医学, 2020, 18(3): 415-418. doi: 10.16766/j.cnki.issn.1674-4152.001261

    CHEN Y H, WAN H F, ZHANG Y X. Effect of interventional intraoperative cerebral oxygen saturation monitoring on postoperative delirium in elderly patients with spinal tuberculosis[J]. Chinese Journal of General Practice, 2020, 18(3): 415-418. doi: 10.16766/j.cnki.issn.1674-4152.001261
    [4]
    ZYWIEL M G, HURLEY R T, PERRUCCIO A V, et al. Health economic implications of perioperative delirium in older patients after surgery for a fragility hip fracture[J]. J Bone Joint Surg Am, 2015, 97(10): 829-836. doi: 10.2106/JBJS.N.00724
    [5]
    徐爱红, 李海平, 苏婷婷, 等. 老年骨质疏松症患者的认知功能特点及相关性[J]. 临床与病理杂志, 2022, 42(5): 1130-1135. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB202205018.htm

    XU A H, LI H P, SU T T, et al. Characteristics and correlation of cognitive function in elderly patients with osteoporosis[J]. Journal of Clinical and Pathological Research, 2022, 42(5): 1130-1135. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB202205018.htm
    [6]
    HERLING S F, DREIJER B, WRIST LAM G, et al. Total intravenous anaesthesia versus inhalational anaesthesia for adults undergoing transabdominal robotic assisted laparoscopic surgery[J]. Cochrane Database Syst Rev, 2017, 4(4): CD011387. DOI: 10.1002/14651858.
    [7]
    PHILIPPOT A, DUBOIS V, LAMBRECHTS K, et al. Impact of physical exercise on depression and anxiety in adolescent inpatients: a randomized controlled trial[J]. J Affect Disord, 2022, 301: 145-153. doi: 10.1016/j.jad.2022.01.011
    [8]
    KHAW J, SUBRAMANIAM P, ABD AZIZ N A, et al. Current update on the clinical utility of MMSE and MoCA for stroke patients in Asia: a systematic review[J]. Int J Environ Res Public Health, 2021, 18(17): 8962. doi: 10.3390/ijerph18178962
    [9]
    LAN Y, YOU Z J, DU R M, et al. Association of olfactory impairment and postoperative cognitive dysfunction in elderly patients[J]. Front Mol Biosci, 2021, 8: 681463. DOI: 10.3389/fmolb.2021.681463.
    [10]
    张晓艳, 田雪筠, 陈肖, 等. 术后认知功能障碍的神经心理学评价及危险因素研究进展[J]. 护理实践与研究, 2022, 19(3): 374-378. https://www.cnki.com.cn/Article/CJFDTOTAL-HLSJ202203014.htm

    ZHANG X Y, TIAN X Y, CHEN X, et al. Research progress in neuropsychological evaluation and risk factors of postoperative cognitive impairment[J]. Nursing Practice and Research, 2022, 19(3): 374-378. https://www.cnki.com.cn/Article/CJFDTOTAL-HLSJ202203014.htm
    [11]
    SUSANO M J, GRASFIELD R H, FRIESE M, et al. Brief preoperative screening for frailty and cognitive impairment predicts delirium after spine surgery[J]. Anesthesiology, 2020, 133(6): 1184-1191.
    [12]
    OBERAI T, LAVER K, CROTTY M, et al. Effectiveness of multicomponent interventions on incidence of delirium in hospitalized older patients with hip fracture: a systematic review[J]. Int Psychogeriatr, 2018, 30(4): 481-492.
    [13]
    颜秀侠, 韩若东, 岳亚杰, 等. 危重症患者ICU治疗后早期认知功能障碍的临床相关因素分析[J]. 中华全科医学, 2020, 18(5): 746-748, 825. doi: 10.16766/j.cnki.issn.1674-4152.001345

    YAN X X, HAN R D, YUE Y J, et al. Clinical study on influencing factors of early cognitive dysfunction in critically ill patients after ICU[J]. Chinese Journal of General Practice, 2020, 18(5): 746-748, 825. doi: 10.16766/j.cnki.issn.1674-4152.001345
    [14]
    于浏, 李桂华, 张望平. 全身麻醉复合右美托咪定对腹腔镜子宫全切术患者围术期应激反应和术后认知功能影响[J]. 中国计划生育学杂志, 2022, 30(5): 1060-1064. https://www.cnki.com.cn/Article/CJFDTOTAL-JHSY202205019.htm

    YU L, LI G H, ZHANG W P. Effects of general anesthesia combined with dexmedetomidine during laparoscopic total hysterectomy of patients on their perioperative stress response and postoperative cognitive function[J]. Chinese Journal of Family Planning, 2022, 30(5): 1060-1064. https://www.cnki.com.cn/Article/CJFDTOTAL-JHSY202205019.htm
    [15]
    吴丽珍, 陈紫玫, 黄春行, 等. 老年股骨颈骨折术后认知功能障碍的危险因素分析及预测模型构建[J]. 护理研究, 2022, 36(1): 22-27. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ202201004.htm

    WU L Z, CHEN Z M, HUANG C X, et al. Risk factors analysis and prediction model construction of postoperative cognitive dysfunction after femoral neck fracture in elderly patients[J]. Chinese Nursing Research, 2022, 36(1): 22-27. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ202201004.htm
    [16]
    刘冬梅, 吴显川, 蒲国士, 等. 老年非全身麻醉腹部手术病人术后认知功能障碍预测模型的构建与验证[J]. 护理研究, 2021, 35(21): 3780-3784. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ202121006.htm

    LIU D M, WU X C, PU G S, et al. Construction and validation of a predictive model for postoperative cognitive dysfunction in elderly patients undergoing abdominal surgery under non-general anesthesia[J]. Chinese Nursing Research, 2021, 35(21): 3780-3784. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ202121006.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (107) PDF downloads(7) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return