Volume 21 Issue 8
Aug.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(8): 1437-1440
CHEN Juanjuan, LI Li, SUN Qi, ZHANG Qian, LI Dongmei. Systematic evaluation of the efficacy and safety of modified prone position ventilation in the treatment of children with ARDS[J]. Chinese Journal of General Practice, 2023, 21(8): 1437-1440. doi: 10.16766/j.cnki.issn.1674-4152.003140
Citation: CHEN Juanjuan, LI Li, SUN Qi, ZHANG Qian, LI Dongmei. Systematic evaluation of the efficacy and safety of modified prone position ventilation in the treatment of children with ARDS[J]. Chinese Journal of General Practice, 2023, 21(8): 1437-1440. doi: 10.16766/j.cnki.issn.1674-4152.003140
shu

Systematic evaluation of the efficacy and safety of modified prone position ventilation in the treatment of children with ARDS

doi: 10.16766/j.cnki.issn.1674-4152.003140

  • Department of Pediatric Intensive Care Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 SK2021A0425

 BYKY2019205skZD

  • Received Date: 2022-07-18
    Available Online: 2023-09-13
    Abstract
  •   Objective  To observe the efficacy and safety of modified prone position ventilation in the treatment of children with acute respiratory distress syndrome (ARDS), to provide a standardized process for the treatment and care of clinical ARDS.  Methods  Fifty children with ARDS hospitalized in the Department of Intensive Care Medicine, the First Affiliated Hospital of Bengbu Medical College from January 2020 to December 2021 were conveniently selected and randomly divided into control group and observation group by using a radom number table method, with 25 cases in each group. The control group was given the traditional prone position ventilation method, and the observation group was given the modified prone position ventilation method. The improvement of respiratory mechanical indexes (oxygenation index, thoracic and pulmonary compliance) and hemodynamic indexes (heart rate, mean arterial pressure) and the occurrence of complications before and after intervention were compared between the two groups.  Results  There was no significant difference in the scores of respiratory mechanics index and hemodynamic index between the two groups before intervention (P>0.05). After prone position ventilation, there were no significant changes in hemodynamic indexes between the two groups (P>0.05). The oxygenation index and chest and lung compliance monitoring scores of the observation group were better than those of the control group, and the differences were statistically significant (all P < 0.05). The incidence of complications (stress injury, vomiting, accidental extubation, facial edema) was 4.0% in the observation group and 28.0% in the control group, and the difference was statistically significant between the two groups (P < 0.05).  Conclusion  The modified prone position ventilation strategy can promote the recovery of respiratory movement, maintain the hemodynamic stability of children with ARDS, and reduce the occurrence of complications such as skin injury and vomiting caused by traditional prone position. Meanwhile, the modified prone position provides effective head and face support, alleviates the edema of face, eyelid or conjunctival caused by conventional prone position, and reduces the occurrence of complications. It is worthy of clinical promotion.

     

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