Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1470-1473
CHEN Zhiqian, YE Xinying, QIAN Yan, GONG Kaizheng, ZHAO Pei. Correlation between multiple chronic conditions and long-term heart failure after acute myocardial infarction[J]. Chinese Journal of General Practice, 2023, 21(9): 1470-1473. doi: 10.16766/j.cnki.issn.1674-4152.003148
Citation: CHEN Zhiqian, YE Xinying, QIAN Yan, GONG Kaizheng, ZHAO Pei. Correlation between multiple chronic conditions and long-term heart failure after acute myocardial infarction[J]. Chinese Journal of General Practice, 2023, 21(9): 1470-1473. doi: 10.16766/j.cnki.issn.1674-4152.003148
shu

Correlation between multiple chronic conditions and long-term heart failure after acute myocardial infarction

doi: 10.16766/j.cnki.issn.1674-4152.003148
  • 1.

    Department of Cardiology, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu 225000, China

Funds:

 81970225

  • Received Date: 2022-12-15
    Available Online: 2023-10-19
    Abstract
  •   Objective  To analyze the incidence of long-term heart failure (HF) in patients with acute myocardial infarction (AMI), and explore the correlation between multiple chronic conditions (MCC) with it.  Methods  An analysis was performed on 355 patients with AMI hospitalized in the Department of Cardiology of Affiliated Hospital of Yangzhou University from January 2016 to December 2018. Patients were divided into HF group (149 cases) and non-HF group (206 cases) according to the outcome, with a median follow-up of 43.0 months. The baseline data of the two groups were retrospectively analyzed. Kaplan-Meier analysis and Cox regression analysis were used to evaluate the role of MCC in long-term HF in patients with AMI. The Cochran-Armitage trend test was used to analysis the relationship between the number of coexisting diseases and the incidence of long-term HF in AMI patients.  Results  (1) Patients in the HF group were older, with lower left ventricular ejection fraction, and had higher GRACE scores and proportion of MCC. The proportion of MCC in the HF group was 1.6 times higher than that in the non-HF group. (2) Age (HR=1.024, 95% CI: 1.003-1.045), low left ventricular ejection fraction (HR=0.963, 95% CI: 0.946-0.980), GRACE scores (HR=1.011, 95% CI: 1.004-1.018) and MCC (HR=1.517, 95% CI: 1.073-2.146) were independent influence factors for long-term HF in AMI patients. (3) The cumulative incidence of HF after AMI was significantly higher in patients with MCC than that in patients without MCC (P < 0.05). (4) There was a positive correlation between the incidence of distant HF and the number of coexisting diseases in AMI patients (P < 0.05).  Conclusion  MCC is an independent risk factor for long-term HF in patients with AMI, which has predictive value for the occurrence of long-term HF in AMI patients, and the incidence of long-term HF after AMI increases with the number of coexisting diseases.

     

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