Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1498-1502
HU Yemei, SHAO Shengsheng, ZHANG Yawen, TANG Hui, LI Jun, SHANG Zhuo. Effect of multidimensional cardiac rehabilitation model on prognosis and Lp-PLA2 in patients with acute myocardial infarction after PCI[J]. Chinese Journal of General Practice, 2023, 21(9): 1498-1502. doi: 10.16766/j.cnki.issn.1674-4152.003155
Citation: HU Yemei, SHAO Shengsheng, ZHANG Yawen, TANG Hui, LI Jun, SHANG Zhuo. Effect of multidimensional cardiac rehabilitation model on prognosis and Lp-PLA2 in patients with acute myocardial infarction after PCI[J]. Chinese Journal of General Practice, 2023, 21(9): 1498-1502. doi: 10.16766/j.cnki.issn.1674-4152.003155
shu

Effect of multidimensional cardiac rehabilitation model on prognosis and Lp-PLA2 in patients with acute myocardial infarction after PCI

doi: 10.16766/j.cnki.issn.1674-4152.003155

  • Heart Center, the Second People' s Hospital of Bengbu, Bengbu, Anhui 233000, China

Funds:

 AHWJ2021b095

  • Received Date: 2023-03-11
    Available Online: 2023-10-19
    Abstract
  •   Objective  To investigate the effects of multidimensional cardiac rehabilitation model on cardiac function, quality of life and plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI).  Methods  A total of 234 AMI patients who underwent PCI in the Second People' s Hospital of Bengbu from January to October 2021 were selected and divided into control group and observation group according to the random number table method, with 117 cases in each group. The control group received general cardiac rehabilitation model intervention, and the experimental group received multidimensional cardiac rehabilitation model intervention. Cardiac function, including left ventricular ejection fraction (LVEF), six-minute walking distance (6MWD), major adverse cardiovascular events (MACE), 36-item short-form (SF-36) score, patient health questionnaire-9 (PHQ-9) score and Lp-PLA2 level were compared between the two groups before intervention, 6 months and 12 months after intervention.  Results  After 6 months and 12 months of intervention, the LVEF and 6MWD of the two groups were higher than those before intervention, and the indexes of the experimental group were significantly better than those of the control group (all P < 0.05). The SF-36 scores of the two groups were higher than those before intervention, the PHQ-9 scores were lower than those before intervention, and there was significant difference between the experimental group and the control group (all P < 0.05). After intervention, the level of Lp-PLA2 in the experimental group was significantly lower than that in the control group (282.54±21.82 vs. 318.66±12.89, t=243.340, P < 0.001).  Conclusion  The multidimensional cardiac rehabilitation model after PCI in AMI patients can reduce the risk of atherosclerotic plaque rupture, effectively improve their cardiac function, reduce adverse cardiovascular events, and improve their quality of life.

     

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