Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1541-1543
CHEN Yuanyuan, ZHANG Lan, PAN Jiahua. Influencing factors for prolonged mechanical ventilation in infants after cardiac surgery with congenital heart disease[J]. Chinese Journal of General Practice, 2023, 21(9): 1541-1543. doi: 10.16766/j.cnki.issn.1674-4152.003165
Citation: CHEN Yuanyuan, ZHANG Lan, PAN Jiahua. Influencing factors for prolonged mechanical ventilation in infants after cardiac surgery with congenital heart disease[J]. Chinese Journal of General Practice, 2023, 21(9): 1541-1543. doi: 10.16766/j.cnki.issn.1674-4152.003165
shu

Influencing factors for prolonged mechanical ventilation in infants after cardiac surgery with congenital heart disease

doi: 10.16766/j.cnki.issn.1674-4152.003165

  • Department of Pediatrics, the First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui 230001, China

Funds:

 2021jyxm1760

  • Received Date: 2023-02-15
    Available Online: 2023-10-19
    Abstract
  •   Objective  To investigate the influencing factors of prolonged mechanical ventilation (PMV) in infants with congenital heart disease (CHD) after cardiopulmonary bypass (CPB) open heart surgery.  Methods  A total of 83 infants with CHD who needed CPB open heart surgery in the First Affiliated Hospital of University of Science and Technology of China from January 2018 to July 2019 were retrospectively analyzed.According to the PMV time, they were divided into early-stage withdrawal group (< 24 h, 60 cases) and delayed-stage withdrawal group (> 24 h, 23 cases).The influencing factors of PMV were analyzed and compared, including month age, body weight, RACHS-1 grade, preoperative pneumonia, left ventricular ejection fraction (LVEF), preoperative pulmonary artery pressure, intraoperative CPB time and aortic cross clamp (ACC) time, intraoperative minimum pH, maximum vasoactive-inotropic score (VIS) in the 24 hours after operation.  Results  There were sixty cases in early-stage withdrawal group and twenty-three cases in delayed-stage withdrawal group.Univariate analysis showed that month age, body weight, preoperative pneumonia, preoperative pulmonary artery pressure, CPB time, ACC time, maximum VIS in the first 24 hour after operation were the influencing factors of PMV (P < 0.05).Multivariate logistic regression analysis showed that CPB time (OR=1.128, 95%CI: 1.008-1.262, P=0.035) and maximum VIS in the first 24 hours after operation (OR=1.233, 95%CI: 1.023-1.485, P=0.028) were the independent influencing factors.  Conclusion  Long CPB time and high maximum VIS in the first 24 hours after operation are the main influencing factors for PMV of infants with CHD after operation.

     

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