Volume 21 Issue 10
Oct.  2023
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REN Qiusheng, WANG Yanfang, HUANG Lijun, GU Xiao, WANG Huaying, PENG Weidong. Effect of deep muscle relaxation on oxygenation of jet ventilation during rigid bronchoscopy procedures[J]. Chinese Journal of General Practice, 2023, 21(10): 1679-1682. doi: 10.16766/j.cnki.issn.1674-4152.003199
Citation: REN Qiusheng, WANG Yanfang, HUANG Lijun, GU Xiao, WANG Huaying, PENG Weidong. Effect of deep muscle relaxation on oxygenation of jet ventilation during rigid bronchoscopy procedures[J]. Chinese Journal of General Practice, 2023, 21(10): 1679-1682. doi: 10.16766/j.cnki.issn.1674-4152.003199

Effect of deep muscle relaxation on oxygenation of jet ventilation during rigid bronchoscopy procedures

doi: 10.16766/j.cnki.issn.1674-4152.003199
Funds:

 2021KY332

  • Received Date: 2023-03-15
    Available Online: 2023-11-23
  •   Objective  The optimal condition of jet ventilation during rigid bronchoscopy is still unclear. This study explores the effect of deep muscle relaxation during rigid bronchoscopy on the oxygenation effect of jet ventilation.  Methods  Sixty-eight patients who received selective treatment for central airway lesions under general anesthesia by rigid bronchoscopy from January 2021 to December 2022 in the Affiliated People's Hospital of Ningbo University were divided into deep muscle relaxation group (group D, n=34) and moderate muscle relaxation group (group M, n=34) by random number table method. After induction of general anesthesia, the patients were inserted rigid bronchoscopy for jet ventilation. Train of four (TOF) stimulation was used to measure the depth of muscle relaxation in group M, and the TOF count was maintained at 1-2. In Group D, the depth of muscle relaxation was measured by post tetanic count (PTC), and the PTC was maintained at 1-2. After operation, atropine and neostigmine antagonized residual muscle relaxation.  Results  There were no significant differences in the overall operation time and operation time between the two groups (all P>0.05). The anesthesia time in group D was shorter than that in group M (P < 0.01). The recovery time, extubation time and muscle relaxant dosage in group D were longer than those in group M (all P < 0.05). The intraoperative hypoxic events [(2.7±0.6) times/person], the use of hypoxic intervention measures (27/33) and the operation suspension time [(7.6±3.5) min] in group D were lower than those in group M [(8.8±2.6) times/person, 33/33, (19.3±5.6) min], and the surgeon satisfaction score in group D [(9.4±0.5) points] was higher than that in group M [(6.2±1.5) points, P < 0.05]. The arterial oxygen partial pressure in group D was higher than that in group M at 15 and 30 min of jet ventilation (all P < 0.05). The number of cases with postoperative sore throat in group D (18/33) was lower than that in group M (26/33, P=0.037).  Conclusion  The application of deep muscle relaxation in rigid bronchoscopy procedures can improve the oxygenation effect of jet ventilation, reduce incidence of hypoxemia, operation suspension time and anesthesia time, improve the satisfaction of operators, and has no effect on the total operation time.

     

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