Volume 21 Issue 10
Oct.  2023
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CHEN Shangtao, LIU Feng, LI Shuangqing. Systemic lupus erythematosus with joint involvement as the first symptom: A case report[J]. Chinese Journal of General Practice, 2023, 21(10): 1810-1812. doi: 10.16766/j.cnki.issn.1674-4152.003230
Citation: CHEN Shangtao, LIU Feng, LI Shuangqing. Systemic lupus erythematosus with joint involvement as the first symptom: A case report[J]. Chinese Journal of General Practice, 2023, 21(10): 1810-1812. doi: 10.16766/j.cnki.issn.1674-4152.003230

Systemic lupus erythematosus with joint involvement as the first symptom: A case report

doi: 10.16766/j.cnki.issn.1674-4152.003230
  • Received Date: 2022-09-19
    Available Online: 2023-11-23
  • This paper reported a 67-year-old male patient with a history of lumbar and knee pain for more than 5 years, and no cause was found after various relevant examinations in multiple medical institutions, only with symptomatic pain relief and rehabilitation treatment, the symptoms were not significantly relieved. After admission, skin lesions on both hands and positive antinuclear antibody were found, systemic lupus erythematosus was considered. After the improvement of relevant examinations, the diagnosis was confirmed, after targeted treatment, the patient improved and was discharged. This case suggests that the onset of systemic lupus erythematosus can be insidious, lacking typical manifestations, and it is difficult to make a diagnosis of systemic lupus erythematosus with joint involvement as the initial symptom. It is suggested that clinicians should screen for immune system diseases according to the situation in the face of atypical joint symptoms for early detection, early diagnosis and early treatment.

     

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  • [1]
    张雪, 孙娟, 谢长好, 等. 心理干预对育龄期系统性红斑狼疮患者的影响[J]. 中华全科医学, 2018, 16(10): 1762-1765. doi: 10.16766/j.cnki.issn.1674-4152.000479

    ZHANG X, SUN J, XIE C H, et al. Effect of psychological intervention on patients with systemic lupus erythematosus of reproductive age[J]. Chinese Journal of General Practice, 2018, 16(10): 1762-1765. doi: 10.16766/j.cnki.issn.1674-4152.000479
    [2]
    郭娟, 叶瑜, 刘玲. 抗细胞膜DNA抗体、抗核抗体、抗心磷脂抗体诊断系统性红斑狼疮的临床价值及与病情发展的关系[J]. 临床医学研究与实践, 2022, 7(8): 109-112. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS202208030.htm

    GUO J, YE Y, LIU L. Clinical value of anti-cell membrane DNA antibody, anti-nuclear antibody and anti-cardiolipin antibody in the diagnosis of systemic lupus erythematosus and its relationship with disease development[J]. Clinical Research and Practice, 2022, 7(8): 109-112. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS202208030.htm
    [3]
    肖泽恩, 谢伟基, 张益民. 补体在系统性红斑狼疮分类标准中的意义[J]. 中国实用内科杂志, 2021, 41(3): 243-246. https://www.cnki.com.cn/Article/CJFDTOTAL-SYNK202103017.htm

    XIAO Z E, XIE W J, ZHANG Y M. Significance of complements in the classification criteria of systemic lupus erythematosus[J]. Chinese Journal of Practical Internal Medicine, 2021, 41(3): 243-246. https://www.cnki.com.cn/Article/CJFDTOTAL-SYNK202103017.htm
    [4]
    ARINGER M, COSTENBADER K, DAIKH D, et al. 2019 European league against rheumatism/American college of rheumatology classification criteria for systemic lupus erythematosus[J]. Ann Rhem Dis, 2019, 78(9): 1151-1159. doi: 10.1136/annrheumdis-2018-214819
    [5]
    杨航, 刘毅. 2019年EULAR/ACR系统性红斑狼疮分类标准解读: 先"入围"再"分类", 诊断治疗更精准[J]. 西部医学, 2019, 31(11): 1643-1645. doi: 10.3969/j.issn.1672-3511.2019.11.002

    YANG H, LIU Y. Interpretation of the classification standard of Euler/ACR systemic lupus erythematosus in 2019[J]. Medical Journal of West China, 2019, 31(11): 1643-1645. doi: 10.3969/j.issn.1672-3511.2019.11.002
    [6]
    夏元睿, 范引光, 方心宇, 等. 系统性红斑狼疮患者皮肤损伤和狼疮性肾炎生物标志物的鉴定[J]. 中华疾病控制杂志, 2021, 25(8): 928-934. https://www.cnki.com.cn/Article/CJFDTOTAL-JBKZ202108012.htm

    XIA Y R, FAN Y G, FANG X Y, et al. Identification for biomarkers of skin lesions and lupus nephritis in patients with systemic lupus erythematosus[J]. Chinese Journal of Disease Control & Prevention, 2021, 25(8): 928-934. https://www.cnki.com.cn/Article/CJFDTOTAL-JBKZ202108012.htm
    [7]
    彭元洪, 钟晓武, 青玉凤, 等. 以全身散在皮疹为首发表现的系统性红斑狼疮1例并文献复习[J]. 中华全科医学, 2022, 20(5): 894-896. doi: 10.16766/j.cnki.issn.1674-4152.002481

    PENG Y H, ZHONG X W, QING Y F, et al. Systemic lupus erythematosus with rash scattered all over the body as the first manifestation: a case report and literature review[J]. Chinese Journal of General Practice, 2022, 20(5): 894-896. doi: 10.16766/j.cnki.issn.1674-4152.002481
    [8]
    钱正月, 温浩, 张秀红. 利伐沙班致皮疹文献病例分析[J]. 药物流行病学杂志, 2020, 29(1): 56-60. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLX202001012.htm

    QIAN Z Y, WEN H, ZHANG X H. Literature analysis of rash caused by Rivaroxaban[J]. Chinese Journal of Pharmacoepidemiology, 2020, 29(1): 56-60. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLX202001012.htm
    [9]
    邱刚, 朱晓伟, 刘石惠. 10%葡萄糖注射液致全身过敏性皮疹伴瘙痒1例[J]. 中国乡村医药, 2020, 27(21): 42. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYY202021027.htm

    QIU G, ZHU X W, LIU S H. A case of systemic allergic rash with pruritus caused by 10% glucose-solution[J]. Chinese Journal of Rural Medicine and Pharmacy, 2020, 27(21): 42. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYY202021027.htm
    [10]
    李丹, 刘洪艳, 王妍, 等. 新型冠状病毒肺炎并发结节性红斑1例[J]. 中国感染与化疗杂志, 2022, 22(2): 223-225. https://www.cnki.com.cn/Article/CJFDTOTAL-KGHL202202020.htm

    LI D, LIU H Y, WANG Y, et al. A case of COVID-19 complicated with erythema nodosum[J]. Chinese Journal of Infection and Chemotherapy, 2022, 22(2): 223-225. https://www.cnki.com.cn/Article/CJFDTOTAL-KGHL202202020.htm
    [11]
    刘小平. 216例感染性皮肤病几种病原体镜检方法对比[J]. 中国真菌学杂志, 2020, 15(4): 223-226. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJXZ202004007.htm

    LIU X P. Comparison of microscopic examination methods of several pathogens in 216 cases ofinfectious dermatosis[J]. Chinese Journal of Mycology, 2020, 15(4): 223-226. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJXZ202004007.htm
    [12]
    舒静, 何强, 陈芳, 等. 发热、多变的皮疹及消化道出血一例分析[J]. 中国全科医学, 2020, 23(8): 985-988. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202008019.htm

    SHU J, HE Q, CHEN F, et al. Fever, variable rashes, and gastrointestinal hemorrhage: a case analysis[J]. Chinese General Practice, 2020, 23(8): 985-988. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202008019.htm
    [13]
    郭慧丽, 黄梓城, 王超, 等. 溃疡性结肠炎合并多形红斑一例[J]. 中华炎性肠病杂志, 2021, 5(1): 102-104.

    GUO H L, HUANG Z C, WANG C, et al. A case of ulcerative colitis complicated with erythema multiforme[J]. Chinese Journal of Inflammatory Bowel Diseases, 2021, 5(1): 102-104.
    [14]
    HU F Q, ZHANG Y P, YIN J, et al. Characterization of autoantibodies and cytokines related to cutaneous lupus erythematosus[J]. Lupus, 2021, 30(2): 315-319.
    [15]
    METRY A M, Al SALMI I, AL BALUSHI F, et al. Systemic lupus erythematosus: symptoms and signs at initial presentations[J]. Antiinflamm Antiallergy Agents Med Chem, 2019, 18(2): 142-150.
    [16]
    ZHANG S, YE Z, LI C, et al. Chinese systemic lupus erythematosus treatment and research group (CSTAR) registry XI: gender impact on long-term outcomes[J]. Lupus, 2019, 28(5): 635-641.
    [17]
    李伟念, 蔡小燕, 林小军, 等. 类风湿关节炎和系统性红斑狼疮发生关节侵蚀相关因素分析[J]. 实用医学杂志, 2019, 35(19): 3057-3062. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ201919018.htm

    LI W N, CAI X Y, LIN X J, et al. Factors associated with erosive arthritis in rheumatoid arthritis and systemic lupus erythematosus[J]. The Journal of Practical Medicine, 2019, 35(19): 3057-3062. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ201919018.htm
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