Volume 21 Issue 12
Dec.  2023
Turn off MathJax
Article Contents
YIN Kaihong, CHENG Yinmeng, ZHANG Tao, KE Xiquan, XU Feng, ZHAO Changdong. Clinical study of endoscopic rubber ring ligation combined with foam sclerosing agent injection in the treatment of internal hemorrhoids of grade Ⅱ to Ⅲ mixed hemorrhoids[J]. Chinese Journal of General Practice, 2023, 21(12): 2027-2030. doi: 10.16766/j.cnki.issn.1674-4152.003282
Citation: YIN Kaihong, CHENG Yinmeng, ZHANG Tao, KE Xiquan, XU Feng, ZHAO Changdong. Clinical study of endoscopic rubber ring ligation combined with foam sclerosing agent injection in the treatment of internal hemorrhoids of grade Ⅱ to Ⅲ mixed hemorrhoids[J]. Chinese Journal of General Practice, 2023, 21(12): 2027-2030. doi: 10.16766/j.cnki.issn.1674-4152.003282

Clinical study of endoscopic rubber ring ligation combined with foam sclerosing agent injection in the treatment of internal hemorrhoids of grade Ⅱ to Ⅲ mixed hemorrhoids

doi: 10.16766/j.cnki.issn.1674-4152.003282
Funds:

 gxgwfx2018052

 JLY20180156

 202223

  • Received Date: 2023-07-04
    Available Online: 2024-01-29
  •   Objective  Exploring the clinical efficacy and safety analysis of endoscopic rubber band ligation (ERBL) combined with foam sclerotherapy (FS) in the treatment of mixed hemorrhoids of grade Ⅱ to Ⅲ.  Methods  A total of 62 patients who underwent mixed hemorrhoid treatment at the Department of Gastroenterology and Gastrointestinal Surgery of Lianyungang Second People's Hospital from September 2020 to May 2022 were retrospectively included. According to different surgical methods, 30 patients who received ERBL combined with FS were included in the treatment group. Thirty-two patients who only underwent traditional surgical external stripping and internal ligation were included in the control group. The operation time, hospitalization time, hospitalization expenses, postoperative complications and clinical efficacy were compared between the two groups of patients. Follow-up for 6 months was conducted to evaluate the clinical effect and safety.  Results  Both groups of patients successfully completed the surgery. The operation time, hospitalization time, and hospitalization expenses in the treatment group were all less than those in the control group, and the differences were statistically significant (all P < 0.05). Six months after surgery, postoperative urinary retention, perianal redness and swelling, anal swelling, and defecation difficulty in the treatment group were all lower than those in the control group (all P < 0.05). The VAS score 24 hours after surgery in the treatment group was lower than that in the control group (U=252.000, P < 0.001). The bleeding situation in the treatment group 1 week after surgery was lower than that in the control group (U=192.500, P < 0.001). Six months after surgery, 25 cases were cured in the treatment group, 4 cases were effective, and 1 case was ineffective or relapsed. In the control group, 19 cases were cured, 7 cases were effective, and 6 cases were ineffective or relapsed. The difference in efficacy between the two groups was statistically significant (U=355.500, P=0.028).  Conclusion  The combination of ERBL and FS is safe and effective in the treatment of internal hemorrhoids in grade Ⅱ to Ⅲ mixed hemorrhoids, with fewer complications and a high cure rate, and is worthy of clinical promotion.

     

  • loading
  • [1]
    鲁振锋, 张秀峰, 沈忠, 等. 外剥内扎术联合荷包缝合术治疗Ⅲ、Ⅳ度混合痔的临床效果分析[J]. 中华全科医学, 2019, 17(4): 574-576, 604. doi: 10.16766/j.cnki.issn.1674-4152.000738

    LU Z F, ZHNAG X F, SHEN Z, et al. Clinical effects of Milligan-Morgan hemorrhoidectomy combined with purse-string suture for grades Ⅲ-Ⅳ mixed hemorrhoid[J]. Chinese Journal of General Practice, 2019, 17(4): 574-576, 604. doi: 10.16766/j.cnki.issn.1674-4152.000738
    [2]
    李帅军, 李梅, 许崇斯, 等. 老年混合痔患者自动痔疮套扎术、吻合器痔上黏膜环切术和改良外剥内扎术的疗效对比[J]. 中国老年学杂志, 2018, 38(2): 403-405. doi: 10.3969/j.issn.1005-9202.2018.02.064

    LI S J, LI M, XU C S, et al. Comparison of the efficacy of automatic hemorrhoid ligation, stapler hemorrhoid mucosal circumcision, and modified external and internal ligation in elderly patients with mixed hemorrhoids[J]. Chinese Journal of Gerontology, 2018, 38(2): 403-405. doi: 10.3969/j.issn.1005-9202.2018.02.064
    [3]
    马凰富, 李佳楠, 李昕, 等. 胶圈套扎术和注射疗法治疗痔病的临床研究现状与思考[J]. 结直肠肛门外科, 2020, 26(3): 280-283.

    MA H F, LI J N, LI X, et al. A review of clinical studies on rubber band ligation and injection therapy for hemorrhoids[J]. Journal of Colorectal & Anal Surgery, 2020, 26(3): 280-283.
    [4]
    DAVIS B R, LEE-KONG S A, MIGALY J, et al. The american society of colon and rectal surgeons clinical practice guidelines for the management of hemorrhoids[J]. Dis Colon Rectum, 2018, 61(3): 284-292. doi: 10.1097/DCR.0000000000001030
    [5]
    秦国涛, 杨丽, 戴春雷, 等. 透明帽辅助结肠镜下聚桂醇不同给药方式硬化疗法治疗Ⅰ、Ⅱ期出血性内痔的临床效果[J]. 中国当代医药, 2021, 28(14): 65-68. doi: 10.3969/j.issn.1674-4721.2021.14.018

    QIN G T, YANG L, DAI C L, et al. Clinical effect of sclerotherapy with different administration methods of lauromacrogol under colonoscopy assisted by transparent cap in the treatment of stage Ⅰ and Ⅱ hemorrhagic internal hemorrhoids[J]. China Modern Medicine, 2021, 28(14): 65-68. doi: 10.3969/j.issn.1674-4721.2021.14.018
    [6]
    中国中西医结合学会大肠肛门病专业委员会. 中国痔病诊疗指南(2020)[J]. 结直肠肛门外科, 2020, 26(5): 519-533.

    Professional Committee of Colorectal and Anorectal Diseases of the Chinese Society of Integrated Traditional Chinese and Western Medicine. Guidelines for the diagnosis and treatment of hemorrhoids in China (2020)[J]. Journal of Colorectal & Anal Surgery, 2020, 26(5): 519-533.
    [7]
    中国医师协会内镜医师分会消化内镜专业委员会, 中国抗癌协会肿瘤内镜学专业委员会. 中国消化内镜诊疗相关肠道准备指南(2019, 上海)[J]. 中华内科杂志, 2019, 58(7): 485-495.

    Digestive Endoscopy Special Committee of Endoscopic Physicians Branch of Chinese Medical Association, Cancer Endoscopy Committee of China Anti Cancer Association. Chinese guideline for bowel preparation for colonoscopy (2019, Shanghai)[J]. Chinese Journal of Internal Medicine, 2019, 58(7): 485-495.
    [8]
    混合痔的诊断依据、证候分类、疗效评定——中华人民共和国中医药行业标准《中医内科病证诊断疗效标准》(ZY/T001.1-94)[J]. 辽宁中医药大学学报, 2017, 19(5): 216.

    Diagnostic criteria, symptom classification, and therapeutic efficacy evaluation for mixed hemorrhoids-Chinese Medicine Industry Standard of the People's Republic of China "Chinese Medicine Internal Medicine Disease Diagnosis and Therapeutic Efficacy Standard" (ZY/T001.1-94)[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2017, 19(5): 216.
    [9]
    张管平, 叶婷, 夏虎平. 多普勒超声引导下痔动脉结扎术加外剥内扎术与TST治疗老年混合痔的临床疗效比较[J]. 现代消化及介入诊疗, 2019, 24(4): 402-404. doi: 10.3969/j.issn.1672-2159.2019.04.019

    ZHANG G P, YE T, XIA H P. Comparison of clinical efficacy between Doppler ultrasound guided hemorrhoid artery ligation combined with external and internal ligation and TST in the treatment of elderly mixed hemorrhoids[J]. Modern Digestion & Intervention, 2019, 24(4): 402-404. doi: 10.3969/j.issn.1672-2159.2019.04.019
    [10]
    黄海鹏, 简弄根, 黄红根, 等. 苦参汤加减熏洗对混合痔外剥内扎术后创面愈合、疼痛及肛门功能的影响[J]. 河南中医, 2023, 43(2): 286-289.

    HUANG H P, JIAN N G, HUANG H G, et al. The influence of modified radix sophorae flavescentis decoction for fumigation and washing on wound healing and pain and anal function after Milligan-Morgan hemorrhoidectomy of mixed hemorrhoids[J]. Henan Traditional Chinese Medicine, 2023, 43(2): 286-289.
    [11]
    张管平, 叶婷, 夏虎平. 多普勒超声引导下痔动脉结扎术加外剥内扎术与TST治疗老年混合痔的临床疗效比较[J]. 现代消化及介入诊疗, 2019, 24(4): 402-405. doi: 10.3969/j.issn.1672-2159.2019.04.019

    ZHANG G P, YE T, XIA H P. Comparison of clinical efficacy between Doppler ultrasound guided hemorrhoid artery ligation combined with external and internal ligation and TST in the treatment of elderly mixed hemorrhoids[J]. Modern Digestion & Intervention, 2019, 24(4): 402-405. doi: 10.3969/j.issn.1672-2159.2019.04.019
    [12]
    孙燕, 李刚, 程海鹤, 等. TST联合聚桂醇注射液治疗Ⅱ、Ⅲ期内痔及混合痔的临床观察[J]. 山东医药, 2018, 58(29): 78-80.

    SUN Y, LI G, CHENG H P, et al. Clinical observation on the treatment of stage Ⅱ and Ⅲ internal hemorrhoids and mixed hemorrhoids using TST combined with polycinnamic alcohol injection[J]. Shandong Medical Journal, 2018, 58(29): 78-80.
    [13]
    蔡筱颖, 沈一, 龚梦娇, 等. 对比聚桂醇泡沫硬化剂与聚桂醇注射液在内痔患者中的疗效及术后并发症[J]. 昆明医科大学学报, 2022, 43(12): 137-141.

    CAI X Y, SHEN Y, GONG M J, et al. Comparison of efficacy and postoperative complications of lauromacrogol foam sclerosant and lauromacrogol injection in patients with internal hemorrhoids[J]. Journal of Kunming Medical University, 2022, 43(12): 137-141.
    [14]
    曾乐. 泡沫硬化剂与原液硬化剂治疗内痔的疗效的meta分析[D]. 南昌: 南昌大学, 2022.

    ZENG L. Meta analysis of the efficacy of foam hardener and stock solution hardener in the treatment of internal hemorrhoids[D]. Nanchang: Nanchang University, 2022.
    [15]
    沈峰, 张飞宇, 瞿春莹, 等. 内镜下泡沫硬化剂注射联合橡皮圈套扎治疗Ⅱ~Ⅲ度内痔的前瞻性临床研究(含视频)[J]. 中华消化内镜杂志, 2021, 38(9): 696-701.

    SHEN F, ZHANG F Y, QU C Y, et al. A prospective clinical study of endoscopic foam sclerotherapy combined with rubber band ligation in the treatment of gradeⅡ - Ⅲ internal hemorrhoids (with video)[J]. Chinese Journal of Digestive Endoscopy, 2021, 38(9): 696-701.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(3)  / Tables(4)

    Article Metrics

    Article views (67) PDF downloads(10) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return