Volume 22 Issue 1
Jan.  2024
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ZHANG Kun, YANG Jian, NIU Shulei, XU Xinming. Application of Constrained, Pareto optimization approach in Monaco system intensity modulation mode for Cervical Cancer Radiotherapy[J]. Chinese Journal of General Practice, 2024, 22(1): 14-17. doi: 10.16766/j.cnki.issn.1674-4152.003320
Citation: ZHANG Kun, YANG Jian, NIU Shulei, XU Xinming. Application of Constrained, Pareto optimization approach in Monaco system intensity modulation mode for Cervical Cancer Radiotherapy[J]. Chinese Journal of General Practice, 2024, 22(1): 14-17. doi: 10.16766/j.cnki.issn.1674-4152.003320

Application of Constrained, Pareto optimization approach in Monaco system intensity modulation mode for Cervical Cancer Radiotherapy

doi: 10.16766/j.cnki.issn.1674-4152.003320
Funds:

 20211665

  • Received Date: 2023-07-18
    Available Online: 2024-03-09
  •   Objective  To explore the application of two optimization methods in Monaco system under intensity modulated radiation therapy (DMLC) and volumetric modulated arc therapy (VMAT) in cervical cancer.  Methods  A total of 40 patients with cervical cancer who received intensity-modulated radiotherapy in Cangzhou People' s Hospital from January 2020 to December 2022 were selected. After IMRT and VMAT, the effects of the two modes were analyzed.  Results  Under Constrained Mode, Dmean [(5 225.41±32.53)cGy vs.(5 205.84±32.99)cGy], Dmax [(5 585.46±51.64)cGy vs.(5 635.99±62.12)cGy], bladder V20 [(78.07±6.31)% vs.(85.68±9.42)%], rectal V20 [(87.58±6.14)% vs.(88.75±5.21)%], rectal V40 [(34.21±6.71)% vs.(37.77±5.41)%], pelvis V20 [(84.74±4.91)% vs.(82.18±4.78)%], pelvis V30 [(51.77±6.73)% vs. (54.73±6.02)%], left femoral head V20 [(42.16±8.40)% vs. (37.37±8.68)%], right femoral head V30 [(9.90±3.43)% vs. (12.32±4.46)%]dose, the differences were significant (P < 0.05). Under the DMLC emphasis, the number of machine jumps in Constrained mode was lower than that in Pareto mode (P < 0.05), under the VMAT emphasis, the number of Pareto mode subfields was lower than that in Constrained mode (P < 0.05), and the number of machine jumps was higher than that in Constrained mode (P < 0.05).  Conclusion  VMAT technology can meet the radiation requirements of cervical cancer patients, and Pareto mode is better for endangering organ protection.

     

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