Volume 22 Issue 1
Jan.  2024
Turn off MathJax
Article Contents
ZHANG Kun, YANG Jian, NIU Shulei, XU Xinming. Application of Constrained, Pareto optimization approach in Monaco system intensity modulation mode for Cervical Cancer Radiotherapy[J]. Chinese Journal of General Practice, 2024, 22(1): 14-17. doi: 10.16766/j.cnki.issn.1674-4152.003320
Citation: ZHANG Kun, YANG Jian, NIU Shulei, XU Xinming. Application of Constrained, Pareto optimization approach in Monaco system intensity modulation mode for Cervical Cancer Radiotherapy[J]. Chinese Journal of General Practice, 2024, 22(1): 14-17. doi: 10.16766/j.cnki.issn.1674-4152.003320

Application of Constrained, Pareto optimization approach in Monaco system intensity modulation mode for Cervical Cancer Radiotherapy

doi: 10.16766/j.cnki.issn.1674-4152.003320
Funds:

 20211665

  • Received Date: 2023-07-18
    Available Online: 2024-03-09
  •   Objective  To explore the application of two optimization methods in Monaco system under intensity modulated radiation therapy (DMLC) and volumetric modulated arc therapy (VMAT) in cervical cancer.  Methods  A total of 40 patients with cervical cancer who received intensity-modulated radiotherapy in Cangzhou People' s Hospital from January 2020 to December 2022 were selected. After IMRT and VMAT, the effects of the two modes were analyzed.  Results  Under Constrained Mode, Dmean [(5 225.41±32.53)cGy vs.(5 205.84±32.99)cGy], Dmax [(5 585.46±51.64)cGy vs.(5 635.99±62.12)cGy], bladder V20 [(78.07±6.31)% vs.(85.68±9.42)%], rectal V20 [(87.58±6.14)% vs.(88.75±5.21)%], rectal V40 [(34.21±6.71)% vs.(37.77±5.41)%], pelvis V20 [(84.74±4.91)% vs.(82.18±4.78)%], pelvis V30 [(51.77±6.73)% vs. (54.73±6.02)%], left femoral head V20 [(42.16±8.40)% vs. (37.37±8.68)%], right femoral head V30 [(9.90±3.43)% vs. (12.32±4.46)%]dose, the differences were significant (P < 0.05). Under the DMLC emphasis, the number of machine jumps in Constrained mode was lower than that in Pareto mode (P < 0.05), under the VMAT emphasis, the number of Pareto mode subfields was lower than that in Constrained mode (P < 0.05), and the number of machine jumps was higher than that in Constrained mode (P < 0.05).  Conclusion  VMAT technology can meet the radiation requirements of cervical cancer patients, and Pareto mode is better for endangering organ protection.

     

  • loading
  • [1]
    刘娜, 张明军, 吴翠娥, 等. 基于Monaco计划系统的最小子野面积设置值对宫颈癌调强放疗计划的影响[J]. 安徽医科大学学报, 2022, 57(5): 811-815. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE202205026.htm

    LIU N, ZHANG M J, WU C E, et al. The impact of setting the minimum field area based on the Monaco planning system on the intensity modulated radiotherapy plan for cervical cancer[J]. Acta Univ Med Anhui, 2022, 57(5): 811-815. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE202205026.htm
    [2]
    周涛琪, 陈俊, 周欣, 等. 基于HSP70信号通路探究三七总皂苷对宫颈癌MPO活性及放疗敏感性的作用机制[J]. 中华全科医学, 2022, 20(4): 565-569. doi: 10.16766/j.cnki.issn.1674-4152.002401

    ZHOU T Q, CHEN J, ZHOU X, et al. Exploring the mechanism of action of Panax notoginseng saponins on MPO activity and radiation sensitivity in cervical cancer based on the HSP70 signaling pathway[J]. Chinese Journal of General Practice, 2022, 20(4): 565-569. doi: 10.16766/j.cnki.issn.1674-4152.002401
    [3]
    SANCHEZ-NIETO B, MEDINA-ASCANIO K N, RODRIGUEZ-MONGUA J L, et al. Study of out-of-field dose in photon radiotherapy: a commercial treatment planning system versus measurements and Monte Carlo simulations[J]. Med Phys, 2020, 47(9): 4616-4625. doi: 10.1002/mp.14356
    [4]
    HASANI M, FARHOOD B, GHORBANI M, et al. Effect of computed tomography number-relative electron density conversion curve on the calculation of radiotherapy dose and evaluation of Monaco radiotherapy treatment planning system[J]. Australas Phys Eng Sci Med, 2019, 42(2): 489-502. doi: 10.1007/s13246-019-00745-6
    [5]
    邓建国, 苏世达, 陈利, 等. MONACO计划系统控制点数量对晚期鼻咽癌动态调强治疗计划质量影响[J]. 中华肿瘤防治杂志, 2021, 28(6): 456-460, 468. https://www.cnki.com.cn/Article/CJFDTOTAL-QLZL202106011.htm

    DENG J G, SU S D, CHEN L, et al. The impact of the number of control points in the MONACO planning system on the quality of dynamic intensity modulated treatment plans for advanced nasopharyngeal carcinoma[J]. Chin J Cancer Prevention and Treatment, 2021, 28(6): 456-460, 468. https://www.cnki.com.cn/Article/CJFDTOTAL-QLZL202106011.htm
    [6]
    AYALA R, RUIZ G, VALDIVIELSO T. Automatizing a nonscripting TPS for optimizing clinical workflow and reoptimizing IMRT/VMAT plansy[J]. Med Dosim, 2019, 44(4): 409-414. doi: 10.1016/j.meddos.2019.02.006
    [7]
    DAMME A V, ROMBAUT J, MAKAR A, et al. Completion surgery after intensity-modulated arc therapy for locally advanced cervical cancer: long-term follow-up and update on surgical outcome and oncologic results of a unique tertiary care single-center retrospective cohort[J]. World J Surg Oncol, 2023, 21(1): 2-11. doi: 10.1186/s12957-022-02878-7
    [8]
    王成, 陈维军, 李玉成, 等. 优化角度分组对宫颈癌容积旋转调强计划剂量分布的影响[J]. 科学技术与工程, 2021, 21(15): 6236-6241. doi: 10.3969/j.issn.1671-1815.2021.15.018

    WANG C, CHEN W J, LI Y C, et al. The effect of optimizing angle grouping on the dose distribution of cervical cancer volume rotation intensity modulation plan[J]. Chin Sci Citation Database, 2021, 21(15): 6236-6241. doi: 10.3969/j.issn.1671-1815.2021.15.018
    [9]
    韩胜, 彭小东, 袁珂, 等. 体电子密度对术后宫颈癌放射治疗计划剂量精确度的影响研究[J]. 中华放射医学与防护杂志, 2021, 41(2): 140-145.

    HAN S, PENG X D, YUAN K, et al. Study on the Effect of Volume Electron Density on the Dose Accuracy of Postoperative Cervical Cancer Radiotherapy Plan[J]. Chin J Radiol Med Prot, 2021, 41(2): 140-145.
    [10]
    陈菲, 张确, 李政欢. 臂架角度增量对宫颈癌术后VMAT计划质量的影响[J]. 医疗卫生装备, 2021, 42(6): 60-64. https://www.cnki.com.cn/Article/CJFDTOTAL-YNWS202106012.htm

    CHEN F, ZHANG Z, LI Z H. The effect of arm angle increment on the quality of VMAT plan after cervical cancer surgery[J]. Chin Med Equipment J, 2021, 42(6): 60-64. https://www.cnki.com.cn/Article/CJFDTOTAL-YNWS202106012.htm
    [11]
    LEI C, HUANG M, LI N, et al. Intensity-modulated radiotherapy combined with intracavitary brachytherapy for locally advanced cervical cancer with uterus didelphys[J]. Gynecol Oncol Rep, 2021, 36(3): 100724. DOI: 10.1016/j.gore.2021.100724.
    [12]
    GOSWAMI B, JAIN R K, YADAV S, et al. A dosimetric study of volumetric arc modulation with rapidArc versus intensity-modulated radiotherapy in cervical cancer patients[J]. J Clin Diagn Res, 2021, 15(5): XC01-XC05. DOI: 10.7860/JCDR/2021/48635.14863.
    [13]
    潘香, 杨毅, 侯宇, 等. 基于Monaco的不同布野方式在左乳腺癌保乳术后调强放疗中的剂量学差异[J]. 实用临床医药杂志, 2021, 25(1): 1-5. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202101001.htm

    PAN X, YANG Y, HOU Y, et al. Dosimetric differences in base note radiotherapy for left breast cancer after breast conserving surgery with different field layout based on Monaco[J]. J Clin Med Prac, 2021, 25(1): 1-5. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202101001.htm
    [14]
    付春鹏, 陈昌舜, 徐智, 等. 基于Monaco计划系统蒙特卡罗算法的脊柱植入钛合金对靶区及周围组织剂量分布的影响研究[J]. 中国医学装备, 2022, 19(6): 21-24. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZB202206005.htm

    FU C P, CHEN C S, XU Z, et al. Study on the effect of spinal implantation of titanium alloy on the dose distribution in the target area and surrounding tissues based on the monte carlo algorithm of the monaco planning system[J]. Chin Med Equipment, 2022, 19(6): 21-24. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZB202206005.htm
    [15]
    柏晗, 吴星娆, 陈飞虎, 等. 宫颈癌外照射Pinnacle与Monaco系统容积调强物理方案的比较分析及方案质量评估模型的创建[J]. 肿瘤预防与治疗, 2019, 32(1): 61-66.

    Comparative analysis of physical schemes for volume intensity modulation of pinnacle and monaco systems for external irradiation of cervical cancer and creation of a quality evaluation model for the schemes[J]. J Canc Control Treat, 2019, 32(1): 61-66.
    [16]
    葛双, 王寻, 叶书成, 等. 宫颈癌双弧容积旋转调强放射治疗中两种优化模式的剂量学比较研究[J]. 中国医学装备, 2020, 17(10): 40-45. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZB202010012.htm

    GE S, WANG X, YE S C, et al. Dosimetric comparison of two optimization modes in dual arc volume rotation intensity modulated radiation therapy for cervical cancer[J]. Chin Med Equipment, 2020, 17(10): 40-45. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZB202010012.htm
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)  / Tables(3)

    Article Metrics

    Article views (93) PDF downloads(7) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return