Volume 22 Issue 1
Jan.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(1): 34-38
ZHENG Kesong, KANG Fang, HAN Mingming, YANG Chengwei, HUANG Xiang, LI Juan. A comparative study on the effect of different anesthesia methods on early postoperative inflammatory indicators and rehabilitation in patients undergoing cesarean section[J]. Chinese Journal of General Practice, 2024, 22(1): 34-38. doi: 10.16766/j.cnki.issn.1674-4152.003325
Citation: ZHENG Kesong, KANG Fang, HAN Mingming, YANG Chengwei, HUANG Xiang, LI Juan. A comparative study on the effect of different anesthesia methods on early postoperative inflammatory indicators and rehabilitation in patients undergoing cesarean section[J]. Chinese Journal of General Practice, 2024, 22(1): 34-38. doi: 10.16766/j.cnki.issn.1674-4152.003325
shu

A comparative study on the effect of different anesthesia methods on early postoperative inflammatory indicators and rehabilitation in patients undergoing cesarean section

doi: 10.16766/j.cnki.issn.1674-4152.003325

  • Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (Anhui Provincial Hospital), Hefei, Anhui 230001, China

Funds:

 2108085MH323

  • Received Date: 2023-08-03
    Available Online: 2024-03-09
    Abstract
  •   Objective  To evaluate the effects of different anaesthetic methods on inflammatory markers and rehabilitation after caesarean section, and provide a reference for the selection of anaesthetic methods for caesarean section surgery.  Methods  A total of 1 759 patients undergoing emergency caesarean section in the Southern District of the First Affiliated Hospital of the University of Science and Technology of China from January 2022 to May 2023 were divided into general anaesthesia group (group G, n=200) and epidural anaesthesia group (group E, n=1 559). The parturients were selected according to specific inclusion and exclusion criteria, and then the parturients in the two groups were matched in a 1∶1 ratio using the propensity score method. The effects of two different anaesthetic methods on white blood cell (WBC), platelet to lymphocyte ratio (PLR), neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR) and postoperative rehabilitation were compared.  Results  WBC, NLR and MLR in group E were significantly higher than those before surgery, while WBC, PLR, NLR and MLR in group G were significantly higher than those before surgery. Compared with group E, the difference of PLR before and after surgery in group G [16.78 (0.16, 29.36) vs.-2.20 (-21.69, 15.17)] was significantly higher (P < 0.05). In group G, the time from induction of anaesthesia to fetal delivery [6 (3, 12) min vs. 43 (32, 54) min] and the time from skin incision to fetal delivery [3 (2, 7) min vs. 7 (6, 12) min] were significantly shortened, whereas the postoperative farting time [44 (39, 46) h vs. 39 (36, 43) h] was significantly longer (P < 0.05). At 5 minutes before skin incision and during skin incision, group E had significantly lower MAP and HR compared to group G (P < 0.05). There were no significant differences in intraoperative blood loss and postoperative hospital stay between the two groups (P>0.05).  Conclusion  Epidural anaesthesia may be more beneficial for the mother' s recovery, while general anaesthesia is appropriate for emergency delivery of the fetus.

     

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