Volume 22 Issue 1
Jan.  2024
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ZHANG Zezheng, BIAN Ailin. Effect of comorbidities on muscle function in elderly hospitalized patients[J]. Chinese Journal of General Practice, 2024, 22(1): 50-54. doi: 10.16766/j.cnki.issn.1674-4152.003329
Citation: ZHANG Zezheng, BIAN Ailin. Effect of comorbidities on muscle function in elderly hospitalized patients[J]. Chinese Journal of General Practice, 2024, 22(1): 50-54. doi: 10.16766/j.cnki.issn.1674-4152.003329
shu

Effect of comorbidities on muscle function in elderly hospitalized patients

doi: 10.16766/j.cnki.issn.1674-4152.003329

  • General Medicine Department, Tianjin First Central Hospital, Tianjin 300000, China

Funds:

 ZC20220

 ZC20159

  • Received Date: 2023-07-25
    Available Online: 2024-03-09
    Abstract
  •   Objective  To evaluate the muscle function of elderly patients by measuring their skeletal muscle mass, skeletal muscle index, grip strength, and exercise metabolic equivalent METs values, and further explore the impact of comorbidity on muscle function in elderly hospitalized patients.  Methods  Elderly patients (aged ≥ 65 years) hospitalized in the General Medicine Department of Tianjin First Central Hospital from September 2021 to December 2021 were selected as the study subjects. The following general information for the enrolled cases were collected: gender, age, admission symptoms, disease diagnosis, and long-term medication status. The bioelectrical impedance method was used to measure the skeletal muscle mass (SMM, kg), skeletal muscle index (SMI), etc. The grip strength of the dominant hand was measured by the grip strength meter to evaluate the muscle strength, and the exercise metabolic equivalent of task METs value was used to evaluate the daily exercise level. Comorbidity status in elderly patients was evaluated, the Charlson comorbidity index (CCI) was calculated. Sarcopenia was screened based on muscle mass and motor function. The correlation between comorbidities, sarcopenia, and motor ability of the study subjects was analyzed.  Results  The prevalence of comorbidities in this study was 100.0% (88 cases), with the main symptoms of admission complaints being head discomfort, precordial discomfort, and palpitations. Among the enrolled cases, the incidence of sarcopenia was 10.2% (9 cases), and there was a statistically significant difference in grip strength among different age groups (P < 0.05). Spearman correlation analysis revealed a negative correlation between grip strength and CCI, age, and body fat rate (P < 0.05). The values of METs were negatively correlated with age (P < 0.05). The detection rate of tumors in patients with sarcopenia was significantly higher than that in patients without sarcopenia (P < 0.001).  Conclusion  The comorbidities of elderly patients admitted to the general practice department are severe. As comorbidities worsen, muscle function decreases, and the performance in grip strength is more pronounced. The measurement of grip strength is more convenient and reproducible than the measurement of skeletal muscle content and skeletal muscle index, making it suitable for large-scale cross-sectional surveys. This suggests that grip strength plays an important role in the comprehensive evaluation of elderly people. Older women have a higher level of daily exercise than men, suggesting that we should remind older male patients to develop exercise habits when managing their health.

     

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