Volume 22 Issue 1
Jan.  2024
Turn off MathJax
Article Contents
XU Daofen, HU Xinxin, GAO Chuchu, CHEN Leilei, MA Dazheng, SUN Yun. Clinical efficacy of acupuncture catgut embedding combined with Hushi Guntan decoction in treating polycystic ovary syndrome with phlegm-dampness internal resistance[J]. Chinese Journal of General Practice, 2024, 22(1): 130-134. doi: 10.16766/j.cnki.issn.1674-4152.003348
Citation: XU Daofen, HU Xinxin, GAO Chuchu, CHEN Leilei, MA Dazheng, SUN Yun. Clinical efficacy of acupuncture catgut embedding combined with Hushi Guntan decoction in treating polycystic ovary syndrome with phlegm-dampness internal resistance[J]. Chinese Journal of General Practice, 2024, 22(1): 130-134. doi: 10.16766/j.cnki.issn.1674-4152.003348

Clinical efficacy of acupuncture catgut embedding combined with Hushi Guntan decoction in treating polycystic ovary syndrome with phlegm-dampness internal resistance

doi: 10.16766/j.cnki.issn.1674-4152.003348
Funds:

 2019ZB121

 Y2020196

 ZY2022014

 2022FSYYZZ28

  • Received Date: 2023-09-14
    Available Online: 2024-03-09
  •   Objective  The purpose of this study is to analyze the application value of acupuncture and catgut embedding and Hushi Guntan Decoction combined with letrozole in patients with polycystic ovary syndrome with phlegm-dampness internal resistance.  Methods  According to the random number table method, 115 patients with polycystic ovary syndrome with phlegm-dampness internal resistance who were treated in Wenzhou Traditional Chinese Medicine Hospital from October 2021 to October 2022 were divided into two groups. A total of 57 cases in the control group were treated with letrozole, and 58 cases in the treatment group were treated with acupuncture and catgut embedding combined with Hushi Guntan Decoction on the basis of the control group. The levels of sex hormones, glucose and lipid metabolism indexes and polycystic ovarian changes were compared between the two groups.  Results  The levels of LH [(8.76±2.08) U/L] and other sex hormones in the treatment group were lower than those in the control group [(10.28±2.29) U/L, t=3.724, P < 0.05]. Glycolipid metabolism levels such as HbA1c [(4.91±0.91)%] in the treatment group were lower than those in the control group [(5.29±0.87)%, t= 2.289, P < 0.05]. The ovarian volume in the treatment group [(6.52±0.95) cm3] was smaller than that in the control group [(7.66±1.02) cm3, t=6.200, P < 0.05]. The rates of ovulation (86.21%, 50/58) and pregnancy (60.34%, 35/58) in the treatment group were higher than those in the control group [68.42% (39/57), 38.60% (22/57), χ2=5.197, 5.439, P < 0.05].  Conclusion  Acupuncture and catgut embedding combined with Hushi Guntan Decoction can reduce BMI and waist-to-hip ratio, improve the levels of sex hormones, glucose and lipid metabolism and polycystic ovarian changes, restore normal ovulation and increase pregnancy rate.

     

  • loading
  • [1]
    SZCZUKO M, KIKUT J, SZCZUKO U, et al. Nutrition strategy and life style in polycystic ovary syndrome-narrative review[J]. Nutrients, 2021, 13(7): 2452. doi: 10.3390/nu13072452
    [2]
    ZHANG Y, CAI M, DILIMULATI D, et al. Correlation between serum uric acid and body fat distribution in patients with polycystic ovary syndrome[J]. Front Endocrinol(Lausanne), 2021, 12: 782808. DOI: 10.3389/fendo.2021.782808.
    [3]
    PENG Q, CHEN X, LIANG X, et al. Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis[J]. Front Endocrinol(Lausanne), 2023, 14: 1070264. DOI: 10.3389/fendo.2023.1070264.
    [4]
    MOINI JAZANI A, NASIMI DOOST AZGOMI H, NASIMI DOOST AZGOMI A, et al. A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS)[J]. Daru, 2019, 27(2): 863-877. doi: 10.1007/s40199-019-00312-0
    [5]
    毛新, 孙淼, 孟小钰, 等. 多囊卵巢综合征合并痤疮患者333例体质类型及在不同中医证型中分布规律和临床特点[J]. 中华中医药杂志, 2020, 35(6): 3081-3084. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202006106.htm

    MAO X, SUN M, MENG X Y, et al. Study on constitution type, distribution rule and clinical characteristics of 333 polycystic ovary syndrome with acne[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2020, 35(6): 3081-3084. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202006106.htm
    [6]
    陈锦明, 张芬, 邓姣, 等. 中医体质类型与多囊卵巢综合征相关性的meta分析[J]. 中华全科医学, 2022, 20(4): 691-695. doi: 10.16766/j.cnki.issn.1674-4152.002432

    CHEN J M, ZHANG F, DENG J, et al. Correlation between TCM constitution and polycystic ovary syndrome: a meta-analysis[J]. Chinese Journal of General Practice, 2022, 20(4): 691-695. doi: 10.16766/j.cnki.issn.1674-4152.002432
    [7]
    LI Y, WU H, GUO Y, et al. Cangfu Daotan Wan alleviates polycystic ovary syndrome with phlegm-dampness syndrome via disruption of the PKP3/ERCC1/MAPK axis[J]. J Ovarian Res, 2023, 16(1): 134. doi: 10.1186/s13048-023-01200-7
    [8]
    潘紫萌, 侯丽辉, 孙淼, 等. 肥胖与代谢综合征对多囊卵巢综合征患者中医体质分布及代谢的影响[J]. 中华中医药杂志, 2022, 37(3): 1656-1661. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202203104.htm

    PAN Z M, HOU L H, SUN M, et al. Effects of obesity and metabolic syndrome on distribution and metabolism of traditional Chinese medicine constitution in PCOS patients[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2022, 37(3): 1656-1661. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202203104.htm
    [9]
    张吉华, 崔寒尽, 王杨, 等. 礞石滚痰汤辅助治疗颅脑损伤后躁狂型精神障碍痰火扰神证19例临床观察[J]. 中医杂志, 2019, 60(5): 400-404. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ201905010.htm

    ZHANG J H, CUI H J, WANG Y, et al. Clinical Observation on Mengshi Guntan Decoction in the Adujuctive Treatment of 19 Cases of Manic Agitation with Phlegm-Fire Disturbing Mind Syndrome after Traumatic Brain Injury[J]. Journal of Traditional Chinese Medicine, 2019, 60(5): 400-404. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ201905010.htm
    [10]
    中华医学会妇产科学分会内分泌学组及指南专家组. 多囊卵巢综合征中国诊疗指南[J]. 中华妇产科杂志, 2018, 53(1): 2-6. https://www.cnki.com.cn/Article/CJFDTOTAL-SFCZ201810010.htm

    Endocrinology Group and Guideline Expert Group of Obstetrics and Gynecology Branch of Chinese Medical Association. Guidelines for diagnosis and treatment of polycystic ovary syndrome in China[J]. Chinese Journal of Obstetrics and Gynecology, 2018, 53(1): 2-6. https://www.cnki.com.cn/Article/CJFDTOTAL-SFCZ201810010.htm
    [11]
    国家中医药管理局. 中医病证诊断疗效标准[S]. 南京: 南京大学出版社, 1994: 233-234. 标准编码: ZY/T001.1-94.

    State administration of traditional chinese medicine. Diagnostic criteria of TCM diseases and syndromes[S]. Nanjing: Nanjing University Press, 1994: 233-234.
    [12]
    高敬书, 朱梦一, 马红丽, 等. 伴或不伴卵巢多囊样改变的多囊卵巢综合征痰湿阻滞型患者临床特征比较[J]. 中医杂志, 2021, 62(5): 428-432. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ202105019.htm

    GAO J S, ZHU Y M, MA H L, et al. Comparison of Clinical Characteristics between Polycystic Ovary Syndrome Patients of Phlegm-Damp Obstruction Pattern with or without Polycystic Ovarian Morphology[J]. Journal of Traditional Chinese Medicine, 2021, 62(5): 428-432. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ202105019.htm
    [13]
    ZHANG N, LI C, GUO Y, et al. Study on the intervention effect of Qi Gong Wan prescription on patients with phlegm-dampness syndrome of polycystic ovary syndrome based on intestinal flora[J]. Evid Based Complement Alternat Med, 2020, 2020: 6389034. DOI: 10.1155/2020/6389034.
    [14]
    甘小利, 邓文华. 任督脉灸联合穴位埋线治疗肥胖型多囊卵巢综合征临床研究[J]. 中国中医药现代远程教育, 2022, 20(18): 98-101. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYY202218034.htm

    GAN X L, DENG W H. Clinical Study on Ren and Du Meridian Moxibustion Combined with Acupoint Catgut Embedding in the Treatment of Obese Polycystic Ovary Syndrome[J]. Chinese Medicine Modern Distance Education of China, 2022, 20(18): 98-101. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYY202218034.htm
    [15]
    XIANG S, XIA M F, SONG J Y, et al. Effect of electro-acupuncture on expression of IRS-1/PI3K/GLUT4 pathway in ovarian granulosa cells of infertile patients with polycystic ovary syndrome-insulin resistance of phlegm-dampness syndrome[J]. Chin J Integr Med, 2021, 27(5): 330-335. doi: 10.1007/s11655-020-3219-z
    [16]
    王颖, 岳虹妤, 陈颖棋, 等. "健脾培元"穴位埋线法治疗围绝经期肥胖: 随机对照试验[J]. 中国针灸, 2023, 43(3): 294-298. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZE202303011.htm

    WANG Y, YUE H Y, CHEN Y Q, et al. Jianpi Peiyuan acupoint thread embedding therapy for perimenopausal obesity: a randomized controlled trial[J]. Chinese Acupuncture and Moxibustion, 2023, 43(3): 294-298. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZE202303011.htm
    [17]
    彭仙, 曹继刚, 肖苏. 加味苍附导痰丸联合穴位埋线治疗肥胖型多囊卵巢综合征临床研究[J]. 陕西中医, 2019, 40(11): 1570-1573. doi: 10.3969/j.issn.1000-7369.2019.11.023

    PEN X, CAO J G, XIAO S. Cangfu Daotan pill combined with acupoint catgut embedding in the treatment of obesity polycystic ovary syndrome[J]. Shaanxi Journal of Traditional Chinese Medicine, 2019, 40(11): 1570-1573. doi: 10.3969/j.issn.1000-7369.2019.11.023
    [18]
    王佳捷, 黄伟, 韦丹, 等. 电针、埋线对单纯性肥胖患者血清瘦素、胰岛素影响的对比研究[J]. 针刺研究, 2019, 44(1): 57-61. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYJ201901011.htm

    WANG J J, HUANG W, WEI D, et al. Comparison of therapeutic effects of electroacupuncture and acupoint catgut embedding in reducing serum leptin and insulin levels in simple obesity patients[J]. Acupuncture Research, 2019, 44(1): 57-61. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYJ201901011.htm
    [19]
    桂晓凤, 吕燕, 张亚男. 苍附益坤汤加减辅助西医治疗痰湿瘀滞型多囊卵巢综合征不孕症临床效果观察[J]. 海南医学, 2023, 34(7): 970-973. https://www.cnki.com.cn/Article/CJFDTOTAL-HAIN202307014.htm

    GUI X F, LYU Y, ZHANG Y N. Clinical effect of Cangfu Yikun decoction plus western medicine on infertility of patients with polycystic ovary syndrome of phlegm dampness stagnation type[J]. Hainan Medical Journal, 2023, 34(7): 970-973. https://www.cnki.com.cn/Article/CJFDTOTAL-HAIN202307014.htm
    [20]
    侯玉清. 苍附益坤汤联合针刺对痰湿瘀滞型多囊卵巢综合征不孕症患者血清性激素水平及妊娠率的影响[J]. 亚太传统医药, 2019, 15(7): 127-128. https://www.cnki.com.cn/Article/CJFDTOTAL-YTCT201907042.htm

    HOU Y Q. Effect of Cangfu Yikun Decoction combined with acupuncture on serum sex hormone level and pregnancy rate of infertility patients with polycystic ovary syndrome of phlegm-dampness and blood stasis type[J]. Asia-Pacific Traditional Medicine, 2019, 15(7): 127-128. https://www.cnki.com.cn/Article/CJFDTOTAL-YTCT201907042.htm
    [21]
    陈静, 梁潇, 管凤丽, 等. 补肾调经法治疗多囊卵巢综合征不孕症有效性与安全性的系统评价[J]. 中草药, 2021, 52(10): 3037-3050. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO202110021.htm

    CHEN J, LIANG X, GUAN F L, et al. Systematic review on efficacy and safety of Bushen Tiaojing therapy in treatment of polycystic ovary syndrome infertility[J]. Chinese Traditional and Herbal Drugs, 2021, 52(10): 3037-3050. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO202110021.htm
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(5)

    Article Metrics

    Article views (175) PDF downloads(7) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return