Volume 22 Issue 2
Feb.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(2): 212-216
WANG Kaiyang, LIU Fengshuang, LIU Yongguo, LI Guoqing, YANG Yining, YU Xiaolin. The correlation between metabolic syndrome and its components with the degree of coronary artery stenosis and clinical outcomes in patients with acute myocardial infarction[J]. Chinese Journal of General Practice, 2024, 22(2): 212-216. doi: 10.16766/j.cnki.issn.1674-4152.003368
Citation: WANG Kaiyang, LIU Fengshuang, LIU Yongguo, LI Guoqing, YANG Yining, YU Xiaolin. The correlation between metabolic syndrome and its components with the degree of coronary artery stenosis and clinical outcomes in patients with acute myocardial infarction[J]. Chinese Journal of General Practice, 2024, 22(2): 212-216. doi: 10.16766/j.cnki.issn.1674-4152.003368
shu

The correlation between metabolic syndrome and its components with the degree of coronary artery stenosis and clinical outcomes in patients with acute myocardial infarction

doi: 10.16766/j.cnki.issn.1674-4152.003368
  • 1.

    Department of Cardiology, Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, Xinjiang 830000, China

Funds:

 2023D01C91

  • Received Date: 2023-07-19
    Available Online: 2024-03-27
    Abstract
  •   Objective  To explore the correlation between metabolic syndrome (MS) with the degree of coronary artery stenosis and prognosis in patients with acute myocardial infarction (AMI).  Methods  There were 726 AMI patients as the subjects, from the Cardiology Department of Xinjiang Uygur Autonomous Region People's Hospital from January 2019 to December 2020. The Gensini score was used to quantitatively assess the degree of coronary artery stenosis and the clinical outcome was defined as major adverse cardiovascular events (MACEs). Multiple linear regression was used to analyze the correlation between MS and its components between Gensini score. Multivariate Cox regression was used to analyze the independent risk factors for MACEs.  Results  There were 348 patients (47.9%) in the MS group and 378 patients (52.1%) in the non-MS group. Compared with the non-MS group, patients in the MS group were older and had more combined hypertension, diabetes, abdominal obesity, dyslipidemia. Waist circumference, systolic blood pressure, fasting blood glucose, blood urea nitrogen, low density lipoprotein cholesterol and Gensini score were higher, hemoglobin levels were lower, clopidogrel utilization rate was higher and the incidence of MACEs was higher, the differences were statistically significant (P < 0.05). Internal comparison showed that Gensini scores were significantly increased in the group of abdominal obesity and elevated fasting blood glucose (P < 0.05). Multiple linear regression analysis results showed that elevated fasting blood glucose and abdominal obesity were independently correlated with Gensini score. Multivariate Cox regression analysis results showed that: diabetes and abdominal obesity were the independent risk factors for MACEs.  Conclusion  Patients with AMI complicated by MS were very common. Abnormal glucose metabolism and abdominal obesity were closely related to the degree of coronary artery stenosis, and significantly affect the prognosis of patients.

     

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