Volume 22 Issue 2
Feb.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(2): 235-239
JIN Xiaowei, ZHOU Sen, ZHOU Qitao, JIANG Yi. Study on the effect of percutaneous acupoint electrical stimulation during perioperative period to prevent cognitive impairment after total knee arthroplasty in the elderly[J]. Chinese Journal of General Practice, 2024, 22(2): 235-239. doi: 10.16766/j.cnki.issn.1674-4152.003373
Citation: JIN Xiaowei, ZHOU Sen, ZHOU Qitao, JIANG Yi. Study on the effect of percutaneous acupoint electrical stimulation during perioperative period to prevent cognitive impairment after total knee arthroplasty in the elderly[J]. Chinese Journal of General Practice, 2024, 22(2): 235-239. doi: 10.16766/j.cnki.issn.1674-4152.003373
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Study on the effect of percutaneous acupoint electrical stimulation during perioperative period to prevent cognitive impairment after total knee arthroplasty in the elderly

doi: 10.16766/j.cnki.issn.1674-4152.003373

  • Department of Anesthesia and Surgery, Wenzhou Integrated Traditional Chinese and Western Medicine Hospital, Wenzhou, Zhejiang 325000, China

Funds:

 2023KY1160

  • Received Date: 2023-10-07
    Available Online: 2024-03-27
    Abstract
  •   Objective  The purpose of this study is to explore the preventive effect of perioperative percutaneous acupoint electrical stimulation on postoperative cognitive dysfunction (POCD) in elderly patients undergoing total knee arthroplasty (TKA).  Methods  A total of 158 elderly patients with knee joint osteoarthritis who underwent elective unilateral TKA at Wenzhou Integrated Traditional Chinese and Western Medicine Hospital from January 2020 to June 2023 were randomly assigned to a control group (79 cases) and an observation group (79 cases) by random number table method. The control group received TKA under general anesthesia, and the observation group received additional perioperative percutaneous acupoint electrical stimulation intervention. The surgical and anesthesia recovery indicators were recorded, perioperative hemodynamic changes were monitored, serum cytokines and brain neurobiochemical indicators were analyzed, and POCD occurrence was followed up 5 days after surgery.  Results  There was no statistically significant difference in intraoperative bleeding volume, total intraoperative infusion volume, surgical duration, anesthesia recovery time, and tracheal intubation time between the two groups (P>0.05). The HR and MAP values of the two groups during skin resection and immediately after autologous knee joint removal were lower than those of 30 minutes before anesthesia induction (P < 0.001). The content of serum TNF-α, IL-6 and IL-1β in the observation group were lower than those in the control group 5 days after surgery (P < 0.001). The content of serum S-100β and NSE in the observation group were lower than those in the control group 5 days after surgery, while BDNF content was higher than that in the control group (P < 0.001). The incidence of POCD 5 days after surgery in the observation group (11.39%, 9/79) was lower than that in the control group (25.32%, 20/79), and the difference was statistically significant (P < 0.05).  Conclusion  Perioperative percutaneous acupoint electrical stimulation can inhibit neuroinflammatory response, alleviate brain tissue damage, regulate brain nerve metabolism function, and can prevent the occurrence of POCD.

     

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