Volume 22 Issue 2
Feb.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(2): 281-283
SHEN Bianhong, WANG Chengpeng, ZHANG Kaiyuan, GAO Kerun, ZHANG Zhiwen, ZHU Chunyan, FANG Ling, TANG Jianping. Effects of repeated transcranial magnetic stimulation on cognitive and social function in patients with first-episode schizophrenia[J]. Chinese Journal of General Practice, 2024, 22(2): 281-283. doi: 10.16766/j.cnki.issn.1674-4152.003384
Citation: SHEN Bianhong, WANG Chengpeng, ZHANG Kaiyuan, GAO Kerun, ZHANG Zhiwen, ZHU Chunyan, FANG Ling, TANG Jianping. Effects of repeated transcranial magnetic stimulation on cognitive and social function in patients with first-episode schizophrenia[J]. Chinese Journal of General Practice, 2024, 22(2): 281-283. doi: 10.16766/j.cnki.issn.1674-4152.003384
shu

Effects of repeated transcranial magnetic stimulation on cognitive and social function in patients with first-episode schizophrenia

doi: 10.16766/j.cnki.issn.1674-4152.003384

  • Department of Psychiatry, Hangzhou Seventh People's Hospital, Hangzhou, Zhejiang 310013, China

Funds:

 2019RC073

  • Received Date: 2023-04-23
    Available Online: 2024-03-27
    Abstract
  •   Objective  To explore the effect of repetitive transcranial magnetic stimulation (rTMS) on cognitive and social function in patients with first-episode schizophrenia, and to provide evidence for clinical treatment.  Methods  A total of 96 patients with schizophrenia admitted to Hangzhou Seventh People's Hospital from February 2019 to February 2022 they were used the random number table method to randomly divide 48 cases into the observation group (with rTMS true stimulation) and the control group (with pseudo-stimulation), and the scores of cognitive functions [repeatable battery for the assessment of neuropsychological status (RBANS)] and social function [scale of social function in psychosis inpatients (SSPI)] and adverse reactions before and after treatment were compared between the two groups.  Results  After one month of treatment, immediate memory, delayed memory, speech function, visuospatial structure, attention and total scores of RBANS in observation group were (45.69±2.31), (46.79±3.15), (33.87±2.25), (35.81±2.91), (53.75±3.82), and (237.75±9.7) points, respectively, and in the control group were (38.62±1.29), (42.65±3.78), (27.75±2.91), (28.62±2.79), (48.85±3.95), (203.96±9.89) points, respectively. The SSPI scale scores of daily living skills, social and sexual activity skills, mobility and interaction, and total SSPI scores in the observation group were (7.84±0.63), (11.76±1.73), (12.72±1.52), and (32.95±1.87) points, respectively, and in the control group were (6.58±0.31), (9.82±1.79), (10.58 ± 1.42), (28.89 ± 1.98) points, respectively. The scores of RBANS and SSPI in the observation group were significantly higher than those in the control group (P < 0.05). There was no significant difference in adverse reactions between the observation group (31.25%, 15/48) and the control group (27.08%, 13/48), χ2=0.202, P=0.653.  Conclusion  rTMS can effectively improve cognitive and social function in patients with first-episode schizophrenia, and has high safety.

     

    • FullText(HTML)
  • loading
    • References(17)
  • [1]
    吕伟, 李美花. 不同频率重复经颅磁刺激对精神分裂症患者性激素水平及认知功能的影响[J]. 中国现代医学杂志, 2020, 30(12): 83-87. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXDY202012015.htm

    LYU W, LI M H. Effects of transcranial magnetic stimulation with different frequencies on sex hormone level and cognitive function in patients with schizophrenia[J]. China Journal of Modern Medicine, 2020, 30(12): 83-87. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXDY202012015.htm
    [2]
    SILVA M A, RESTREPO D. Functional recovery in schizophrenia[J]. Rev Colomb Psiquiatr (Engl Ed), 2019, 48(4): 252-260.
    [3]
    邵小惠. 重复经颅磁刺激在精神分裂症患者认知功能障碍康复中的作用[J]. 黑龙江医药, 2020, 33(4): 928-930. https://www.cnki.com.cn/Article/CJFDTOTAL-HJYY202004089.htm

    SHAO X H. The role of repetitive transcranial magnetic stimulation in the rehabilitation of cognitive dysfunction in patients with schizophrenia[J]. Heilongjiang Medicine Journal, 2020, 33(4): 928-930. https://www.cnki.com.cn/Article/CJFDTOTAL-HJYY202004089.htm
    [4]
    YANG L L, ZHAO D, KONG L L, et al. High-frequency repetitive transcranial magnetic stimulation(rTMS) improves neurocognitive function in bipolar disorder[J]. J Affect Disord, 2019, 246: 851-856. doi: 10.1016/j.jad.2018.12.102
    [5]
    中华医学会精神科分会. 中国精神疾病分类方案与诊断标准[M]. 3版. 济南: 山东科学技术出版社, 2001: 75-78.

    Chinese Medical Association Psychiatric Branch. Classification scheme and diagnostic criteria of mental diseases in China[M]. 3rd edition. Jinan: Shandong Science and Technology Press, 2001: 75-78.
    [6]
    余金鸣, 胡新伟, 牛亚辉. 高频重复经颅磁刺激对慢性精神分裂症患者吸烟及认知功能的影响[J]. 中国现代药物应用, 2022, 16(7): 6-9. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWYY202207002.htm

    YU J M, HU X W, NIU Y J. Effect of high-frequency repetitive transcranial magnetic stimulation on smoking and cognitive function in patients with chronic schizophrenia[J]. Chinese Journal of Modern Drug Application, 2022, 16(7): 6-9. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWYY202207002.htm
    [7]
    王鑫, 李盛延, 赵顺程, 等. 经颅直流电刺激对精神分裂症患者认知功能、社会功能及神经营养因子的影响[J]. 临床与病理杂志, 2022, 42(6): 1403-1409. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB202206020.htm

    WANG X, LI S Y, ZHAO S C, et al. Effects of transcranial direct current stimulation on cognitive function, social function and neurotrophic factors in patients with schizophrenia[J]. Journal of Clinical and Pathological Research, 2022, 42(6): 1403-1409. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB202206020.htm
    [8]
    沈志华, 周相宜, 韩雨, 等. 精神分裂症浓缩版社会认知交互训练干预程序的设计及应用评价[J]. 中华全科医学, 2023, 21(4): 641-645. doi: 10.16766/j.cnki.issn.1674-4152.002950

    SHEN Z H, ZHOU X Y, HAN Y, et al. Design and application evaluation of condensed version of social cognition interaction training intervention program in schizophrenia[J]. Chinese Journal of General Practice, 2023, 21(4): 641-645. doi: 10.16766/j.cnki.issn.1674-4152.002950
    [9]
    郝蕊, 刘寰忠, 夏磊, 等. 儿童青少年首发精神分裂症认知障碍特征[J]. 安徽医科大学学报, 2018, 53(7): 1118-1121. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE201807027.htm

    HAO R, LIU H Z, XIA L, et al. Cognitive impairment in adolescents with first-episode schizophrenia[J]. Acta Universitatis Medicinalis Anhui, 2018, 53(7): 1118-1121. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE201807027.htm
    [10]
    杨丹, 关涛. 重复经颅磁刺激联合帕利哌酮对精神分裂症患者认知功能的影响[J]. 国际精神病学杂志, 2021, 48(1): 33-35, 41. https://www.cnki.com.cn/Article/CJFDTOTAL-GWYJ202101011.htm

    YANG D, GUAN T. Effect of repetitive transcranial magnetic stimulation combined with paliperidone on cognitive function of schizophrenic patients[J]. Journal Of International Psychiatry, 2021, 48(1): 33-35, 41. https://www.cnki.com.cn/Article/CJFDTOTAL-GWYJ202101011.htm
    [11]
    关恒永, 李喜泼, 潘艳芬, 等. 经颅磁刺激与精神分裂症认知障碍[J]. 精神医学杂志, 2018, 31(4): 308-311. https://www.cnki.com.cn/Article/CJFDTOTAL-SDJB201804021.htm

    GUAN H Y, LI X P, PAN Y F, et al. Transcranial magnetic stimulation and cognitive impairment in schizophrenia[J]. Journal of Psychiatry, 2018, 31(4): 308-311. https://www.cnki.com.cn/Article/CJFDTOTAL-SDJB201804021.htm
    [12]
    贺守彬. 高频重复经颅磁刺激对精神分裂症患者认知功能的影响[J]. 中国医药指南, 2020, 18(33): 58-59. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK202033026.htm

    HE S B. Effect of high frequency repetitive transcranial magnetic stimulation on cognitive function of schizophrenia[J]. Guide of China Medicine, 2020, 18(33): 58-59. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK202033026.htm
    [13]
    陆晶晶, 孙莲芳, 张莉. 重复经颅磁刺激治疗对精神分裂症患者阴性症状、认知功能、脑内神经递质及血清炎症因子的影响[J]. 临床与病理杂志, 2022, 42(8): 1945-1951. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB202208025.htm

    LU J J, SUN L F, ZHANG L. Effects of repetitive transcranial magnetic stimulation on negative symptoms, cognitive function, brain neurotransmitters and serum inflammatory factors in patients with schizophrenia[J]. Journal of Clinical and Pathological Research, 2022, 42(8): 1945-1951. https://www.cnki.com.cn/Article/CJFDTOTAL-WYSB202208025.htm
    [14]
    蒋晓春, 黄婉立, 陈燕娣, 等. 重复经颅磁刺激对精神分裂症患者认知功能的影响[J]. 中国现代医生, 2021, 59(19): 22-25. https://www.cnki.com.cn/Article/CJFDTOTAL-ZDYS202119007.htm

    JIANG X C, HUANG W L, CHEN Y D, et al. Effect of repeated transcranial magnetic stimulation on the cognitive function of patients with schizophrenia[J]. China Modern Doctor, 2021, 59(19): 22-25. https://www.cnki.com.cn/Article/CJFDTOTAL-ZDYS202119007.htm
    [15]
    何孔亮, 梁丹丹, 李智勇, 等. 高精度经颅直流电刺激对精神分裂症患者认知及社会功能的影响[J]. 安徽医科大学学报, 2020, 55(11): 1787-1791. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE202011028.htm

    HE K L, LIANG D D, LI Z Y, et al. Effects of high definition transcranial direct current stimulation on cognitive and social functions in convalescent schizophrenics[J]. Acta Universitatis Medicinalis Anhui, 2020, 55(11): 1787-1791. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE202011028.htm
    [16]
    朱虹, 职利花, 贾竑晓. 齐拉西酮治疗对精神分裂症患者认知功能和生活质量的治疗效果研究[J]. 首都医科大学学报, 2018, 39(2): 199-203. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYD201802009.htm

    ZHU H, ZHI L H, JIA H X. Evaluating the efficacy of ziprasidone in improving cognition, quality of life and clinical symptom in schizophrenia[J]. Journal of Capital Medical University, 2018, 39(2): 199-203. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYD201802009.htm
    [17]
    倪花, 朱旻, 曹俊, 等. 重复经颅磁刺激对首发精神分裂症患者认知及社会功能的影响[J]. 临床精神医学杂志, 2022, 32(6): 434-437. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS202206004.htm

    NI H, ZHU M, CAO J, et al. Effect of repeated transcranial magnetic stimulation on cognitive and social function in first-episode schizophrenia[J]. Journal of Clinical Psychiatry, 2022, 32(6): 434-437. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS202206004.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (328) PDF downloads(16) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return