Relationship between whole blood iron and hyperuricemia in Kailuan study population

WANG Jierui; ZHU Baojie; WANG Li; SHI Huijing; CUI Liufu; SHU Rong; SONG Haicheng; XU Aigang; ZHANG Yanshu

doi:10.16766/j.cnki.issn.1674-4152.003411

Volume 22 Issue 3

Mar. 2024

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Article Navigation > Chinese Journal of General Practice > 2024 > 22(3): 398-401

WANG Jierui, ZHU Baojie, WANG Li, SHI Huijing, CUI Liufu, SHU Rong, SONG Haicheng, XU Aigang, ZHANG Yanshu. Relationship between whole blood iron and hyperuricemia in Kailuan study population[J]. Chinese Journal of General Practice, 2024, 22(3): 398-401. doi: 10.16766/j.cnki.issn.1674-4152.003411

Citation:

WANG Jierui, ZHU Baojie, WANG Li, SHI Huijing, CUI Liufu, SHU Rong, SONG Haicheng, XU Aigang, ZHANG Yanshu. Relationship between whole blood iron and hyperuricemia in Kailuan study population[J]. Chinese Journal of General Practice, 2024, 22(3): 398-401. doi: 10.16766/j.cnki.issn.1674-4152.003411

Citation:

WANG Jierui, ZHU Baojie, WANG Li, SHI Huijing, CUI Liufu, SHU Rong, SONG Haicheng, XU Aigang, ZHANG Yanshu. Relationship between whole blood iron and hyperuricemia in Kailuan study population[J]. Chinese Journal of General Practice, 2024, 22(3): 398-401. doi: 10.16766/j.cnki.issn.1674-4152.003411

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Relationship between whole blood iron and hyperuricemia in Kailuan study population

doi: 10.16766/j.cnki.issn.1674-4152.003411

WANG Jierui^{1, 2}
, ZHU Baojie¹
, WANG Li³
, SHI Huijing²
, CUI Liufu²
, SHU Rong²
, SONG Haicheng²
, XU Aigang⁴
, ZHANG Yanshu^{1
,
,}

1.
School of Public Health, North China University of Science and Technology, Tangshan, Hebei 063210, China

Funds:

20231857

Received Date: 2023-08-04
Available Online: 2024-05-27

Abstract

Abstract

Objective To explore the relationship between whole blood iron level and hyperuricemia in Kailuan study population, and to provide evidence for the early prevention of hyperuricemia. Methods A cross-sectional study was conducted in 3 579 employees and retirees of Kailuan Group who participated in the health examination and completed the whole blood iron test in Linxi Hospital, Majiagou Hospital and Jinggezhuang Hospital from August, 2017 to May, 2018. According to the level of serum uric acid, the subjects were divided into normal serum uric acid group (n=2 983) and hyperuricemia group (n=596). Multivariate logistic regression model was used to analyze the association between whole blood iron (divided into Q1 to Q3 three subgroups according to tertiles) and hyperuricemia, and the effect of different ages on the association between whole blood iron and hyperuricemia was analyzed. Results The whole blood iron in hyperuricemia group [(464.73±104.05) mg/L] was significantly higher than that in normal serum uric acid group [(420.96±109.60) mg/L, P < 0.001]. Multivariate logistic regression analysis showed that after adjusting for other confounding factors, compared with the whole blood iron Q1 group, the OR value (95% CI) of hyperuricemia in the whole blood iron Q3 group was 1.989 (1.487-2.661). In the subjects aged < 60 years, the OR value (95% CI) of hyperuricemia in the whole blood iron Q3 group was 2.304 (1.539-3.450), while which was 1.269 (0.818-1.969) in the subjects aged ≥60 years. In sensitivity analysis, compared with the whole blood iron Q1 group, the OR value (95% CI) of hyperuricemia in the whole blood iron Q3 group was 2.018 (1.499-2.716). Conclusion Higher whole blood iron level is associated with an increased risk of hyperuricemia, especially in people younger than 60 years old.
- Serum uric acid,
- Hyperuricemia,
- Whole blood iron,
- Kailuan study population

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Relationship between whole blood iron and hyperuricemia in Kailuan study population

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