Volume 22 Issue 4
Apr.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(4): 551-554
ZHANG Lanlan, HUANG Haishen, LI Junchao, CHENG Shuai. Evaluation effect and clinical application value of CT angiography on plaque status and luminal stenosis in patients with coronary heart disease[J]. Chinese Journal of General Practice, 2024, 22(4): 551-554. doi: 10.16766/j.cnki.issn.1674-4152.003447
Citation: ZHANG Lanlan, HUANG Haishen, LI Junchao, CHENG Shuai. Evaluation effect and clinical application value of CT angiography on plaque status and luminal stenosis in patients with coronary heart disease[J]. Chinese Journal of General Practice, 2024, 22(4): 551-554. doi: 10.16766/j.cnki.issn.1674-4152.003447
shu

Evaluation effect and clinical application value of CT angiography on plaque status and luminal stenosis in patients with coronary heart disease

doi: 10.16766/j.cnki.issn.1674-4152.003447
  • 1.

    CT Room, the Seventh People' s Hospital of Zhengzhou Zhengzhou, Henan 450012, China

Funds:

 LHGJ20210754

  • Received Date: 2023-11-22
    Available Online: 2024-05-29
    Abstract
  •   Objective  To evaluate the evaluation effect and clinical application value of CT angiography (CTA) on plaque status and lumen stenosis in patients with coronary heart disease, in order to provide reference for clinical search for appropriate non-invasive examination methods.  Methods  The clinical data of 166 patients with coronary heart disease admitted to the Seventh People' s Hospital of Zhengzhou from October 2019 to October 2022 were retrospectively analyzed. Coronary angiography (CAG) was used as the "gold standard" to calculate the consistency of CTA and CAG results. The types of coronary segmental plaque in patients with different degrees of stenosis were compared based on CTA, and the effects of coronary plaque characteristics and stenosis degree on the risk of major adverse cardiac events (MACE) were analyzed.  Results  A total of 172 coronary stenosis lesions were detected by CAG, and the sensitivity, specificity and coincidence rate of CTA were 96.51% (166/172), 71.54% (352/492) and 78.01% (518/664), respectively, which were in good agreement with the results of CAG (Kappa=0.818, P < 0.001). A total of 89 coronary plaques were detected by CTA. The proportions of non-calcified plaques (35.71%, 10/28) and mixed plaques (32.14%, 9/28) in the mild stenosis segments were lower than those in the moderate/severe stenosis segments [57.37%(35/61), 39.34%(24/61)]. The proportion of calcified plaques in mild stenosis segments (32.14%, 9/28) was higher than that in moderate/severe stenosis segments (3.27%, 2/61), and the difference was statistically significant (P < 0.05). Non-calcified plaque volume, plaque length and lumen diameter stenosis rate were independent risk factors for MACE (P < 0.001).  Conclusion  CTA can accurately evaluate the plaque status and lumen stenosis in patients with coronary heart disease.

     

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