Volume 22 Issue 4
Apr.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(4): 551-554
ZHANG Lanlan, HUANG Haishen, LI Junchao, CHENG Shuai. Evaluation effect and clinical application value of CT angiography on plaque status and luminal stenosis in patients with coronary heart disease[J]. Chinese Journal of General Practice, 2024, 22(4): 551-554. doi: 10.16766/j.cnki.issn.1674-4152.003447
Citation: ZHANG Lanlan, HUANG Haishen, LI Junchao, CHENG Shuai. Evaluation effect and clinical application value of CT angiography on plaque status and luminal stenosis in patients with coronary heart disease[J]. Chinese Journal of General Practice, 2024, 22(4): 551-554. doi: 10.16766/j.cnki.issn.1674-4152.003447
shu

Evaluation effect and clinical application value of CT angiography on plaque status and luminal stenosis in patients with coronary heart disease

doi: 10.16766/j.cnki.issn.1674-4152.003447
  • 1.

    CT Room, the Seventh People' s Hospital of Zhengzhou Zhengzhou, Henan 450012, China

Funds:

 LHGJ20210754

  • Received Date: 2023-11-22
    Available Online: 2024-05-29
    Abstract
  •   Objective  To evaluate the evaluation effect and clinical application value of CT angiography (CTA) on plaque status and lumen stenosis in patients with coronary heart disease, in order to provide reference for clinical search for appropriate non-invasive examination methods.  Methods  The clinical data of 166 patients with coronary heart disease admitted to the Seventh People' s Hospital of Zhengzhou from October 2019 to October 2022 were retrospectively analyzed. Coronary angiography (CAG) was used as the "gold standard" to calculate the consistency of CTA and CAG results. The types of coronary segmental plaque in patients with different degrees of stenosis were compared based on CTA, and the effects of coronary plaque characteristics and stenosis degree on the risk of major adverse cardiac events (MACE) were analyzed.  Results  A total of 172 coronary stenosis lesions were detected by CAG, and the sensitivity, specificity and coincidence rate of CTA were 96.51% (166/172), 71.54% (352/492) and 78.01% (518/664), respectively, which were in good agreement with the results of CAG (Kappa=0.818, P < 0.001). A total of 89 coronary plaques were detected by CTA. The proportions of non-calcified plaques (35.71%, 10/28) and mixed plaques (32.14%, 9/28) in the mild stenosis segments were lower than those in the moderate/severe stenosis segments [57.37%(35/61), 39.34%(24/61)]. The proportion of calcified plaques in mild stenosis segments (32.14%, 9/28) was higher than that in moderate/severe stenosis segments (3.27%, 2/61), and the difference was statistically significant (P < 0.05). Non-calcified plaque volume, plaque length and lumen diameter stenosis rate were independent risk factors for MACE (P < 0.001).  Conclusion  CTA can accurately evaluate the plaque status and lumen stenosis in patients with coronary heart disease.

     

    • FullText(HTML)
  • loading
    • References(20)
  • [1]
    杨玲, 杜雪平. 社区规范管理的稳定性冠心病患者生活质量研究[J]. 中华全科医学, 2023, 21(11): 1898-1902. doi: 10.16766/j.cnki.issn.1674-4152.003253

    YANG L, DU X P. Research on the quality of life in patients with stable coronary artery disease under standardized management in community[J]. Chinese Journal of General Practice, 2023, 21(11): 1898-1902. doi: 10.16766/j.cnki.issn.1674-4152.003253
    [2]
    RAJA J, SEITA M P, YEDLAPATI N, et al. Can computed fractional flow reserve coronary CT angiography (FFRCT) offer an accurate noninvasive comparison to invasive coronary angiography (ICA)?[J]. Curr Probl Cardiol, 2020, 46(3): 100642. DOI: 10.1016/j.cpcardiol.2020.100642.
    [3]
    丁华永. CTA在冠心病冠脉狭窄程度及斑块状态评估中的应用[J]. 中国CT和MRI杂志, 2022, 20(4): 76-78. doi: 10.3969/j.issn.1672-5131.2022.04.025

    DING H Y. Application of CTA in the Assessment of Coronary Artery Stenosis Degree and Plaque Status of Coronary Heart Disease[J]. Chinese Journal of CT and MRI, 2022, 20(4): 76-78. doi: 10.3969/j.issn.1672-5131.2022.04.025
    [4]
    DIAS F, RAMOS R, MODAS D P, et al. Optimizing diagnosis of obstructive coronary artery disease by CT angiography: RCT' s final results and 12-months follow-up[J]. Eur Heart J, 2020, 245(9): 112-117.
    [5]
    高润霖. 进一步改善稳定性冠心病的诊治: 浅谈"中国稳定性冠心病诊断与治疗指南"亮点[J]. 中华心血管病杂志, 2018, 46(11): 833-836. doi: 10.3760/cma.j.issn.0253-3758.2018.11.002

    GAO R L. Further improvement of diagnosis and treatment of stable coronary heart disease: highlights of the "Chinese guidelines for the diagnosis and treatment of stable coronary heart disease"[J]. Chinese Journal of Cardiology, 2018, 46(11): 833-836. doi: 10.3760/cma.j.issn.0253-3758.2018.11.002
    [6]
    高鹤, 吴培香, 肖利允, 等. 穴位刺激治疗冠心病心绞痛有效性和安全性的meta分析[J]. 中华全科医学, 2023, 21(4): 698-703. doi: 10.16766/j.cnki.issn.1674-4152.002963

    GAO H, WU P X, XIAO L Y, et al. Efficacy and safety of acupoint stimulation in the treatment of angina pectoris caused by coronary heart disease: A meta-analysis[J]. Chinese Journal of General Practice, 2023, 21(4): 698-703. doi: 10.16766/j.cnki.issn.1674-4152.002963
    [7]
    KOLOSSVARY M, GERSTENBLITH G, BLUEMKE D A, et al. Contribution of risk factors to the development of coronary atherosclerosis as confirmed via coronary CT angiography: a longitudinal radiomics-based study[J]. Radiology, 2021, 299(1): 97-106. doi: 10.1148/radiol.2021203179
    [8]
    蒋瑞静, 马晓璇, 李相生, 等. 320排容积CT冠状动脉血管造影诊断飞行人员冠心病应用价值研究[J]. 人民军医, 2020, 63(7): 656-658. https://www.cnki.com.cn/Article/CJFDTOTAL-RMJZ202007010.htm

    JIANG R J, MA X X, LI X S, et al. Study on the application value of 320-row volumetric CT coronary angiography for diagnosis of coronary artery disease in flight crew[J]. People' s Military Surgeon, 2020, 63(7): 656-658. https://www.cnki.com.cn/Article/CJFDTOTAL-RMJZ202007010.htm
    [9]
    ZABOLI A, AUSSERHOFER D, SIBILIO S, et al. Effect of the emergency department assessment of chest pain score on the triage performance in patients with chest pain[J]. Am J Cardiol, 2021, 161(9): 12-18.
    [10]
    冯晓荣, 周旭辉, 李锦, 等. 64层螺旋CT双低冠状动脉成像对钙化斑块诊断准确性的研究[J]. 医学影像学杂志, 2021, 31(8): 1315-1320. https://www.cnki.com.cn/Article/CJFDTOTAL-XYXZ202108015.htm

    FENG X R, ZHOU X H, LI J, et al. Study on the accuracy of 64-slice spiral CT double low coronary angiography in diagnosis of calcified plaques[J]. Journal of Medical Imaging, 2021, 31(8): 1315-1320. https://www.cnki.com.cn/Article/CJFDTOTAL-XYXZ202108015.htm
    [11]
    于昊冉, 刘挨师. CCTA在评估冠状动脉粥样硬化易损斑块中的应用价值[J]. 中国CT和MRI杂志, 2023, 21(5): 180-182. doi: 10.3969/j.issn.1672-5131.2023.05.062

    YU H R, LIU A S. Application Value of CCTA in Evaluating Vulnerable Coronar y Atherosclerotic Plaques[J]. Chinese Journal of CT and MRI, 2023, 21(5): 180-182. doi: 10.3969/j.issn.1672-5131.2023.05.062
    [12]
    孙萍, 张怡, 王华斌, 等. MSCTA对冠心病患者冠状动脉狭窄程度及斑块稳定性的评估价值分析[J]. 中国临床医学影像杂志, 2021, 32(12): 865-868. https://www.cnki.com.cn/Article/CJFDTOTAL-LYYX202112008.htm

    SUN P, ZHANG Y, WANG H B, et al. Analysis of the evaluation value of MSCTA on coronary artery stenosis and plaque stability in patients with coronary heart disease[J]. Journal of China Clinic Medical Imaging, 2021, 32(12): 865-868. https://www.cnki.com.cn/Article/CJFDTOTAL-LYYX202112008.htm
    [13]
    HOSHINO M, YANG S, SUGIYAMA T, et al. Characteristic findings of microvascular dysfunction on coronary computed tomography angiography in patients with intermediate coronary stenosis[J]. Eur Radiol, 2021, 31(12): 9198-9210. doi: 10.1007/s00330-021-07909-7
    [14]
    宋军锋. 冠状动脉造影结合斑块钙化积分对冠心病患者冠状动脉狭窄的评估价值[J]. 中国药物与临床, 2020, 20(20): 3455-3457. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC202020047.htm

    SONG J F. Evaluation value of coronary artery stenosis in patients with coronary artery disease by coronary angiography combined with plaque calcification score[J]. Chinese Remedies & Clinics, 2020, 20(20): 3455-3457. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC202020047.htm
    [15]
    孙欣杰, 徐怡, 朱晓梅, 等. 基于冠状动脉CTA的FFRCT与斑块特征对冠心病患者主要不良心脏事件的预测价值[J]. 中国医学计算机成像杂志, 2021, 27(4): 296-301. doi: 10.3969/j.issn.1006-5741.2021.04.005

    SUN X J, XU Y, ZHU X M, et al. The Predictive Value of Coronary CTA-derived Fractional Flow Reserve and Atherosclerosis Plaque Characteristics for Major Adverse Cardiac Events in Patients with Coronary Artery Disease[J]. Chinese Computed Medical Imaging, 2021, 27(4): 296-301. doi: 10.3969/j.issn.1006-5741.2021.04.005
    [16]
    苗珂, 葛洪, 夏蕾, 等. CT血管造影在冠状动脉狭窄程度及其斑块类型评估中的应用价值[J]. 实用心脑肺血管病杂志, 2022, 30(2): 116-119. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXL202202022.htm

    MIAO K, GE H, XIA L, et al. Application Value of CT Angiography in Evaluating the Degree of Coronary Artery Stenosis and Plaque Type[J]. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease, 2022, 30(2): 116-119. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXL202202022.htm
    [17]
    邓以川, 李川, 颜小杭, 等. CT血管成像技术评估血液因子在冠状动脉硬化狭窄的相关性研究[J]. 实用放射学杂志, 2021, 37(4): 567-570, 602. doi: 10.3969/j.issn.1002-1671.2021.04.013

    DENG Y C, LI C, YAN X H, et al. Study on correlation of blood factors in coronary artery stenosis based on CT angiography[J]. Journal of Practical Radiology, 2021, 37(4): 567-570, 602. doi: 10.3969/j.issn.1002-1671.2021.04.013
    [18]
    HADA M, KANAJI Y, UENO H, et al. Diagnostic value of myocardial perfusion CT to detect coexisting microvascular dysfunction in patients with obstructive epicardial coronary disease[J]. Eur Heart J, 2020, 29(1): 16-19.
    [19]
    沈沁, 张骁, 吴婷, 等. 冠状动脉CT血管成像钙化积分对慢性心绞痛患者冠状动脉病变及预后的评估价值[J]. 实用临床医药杂志, 2022, 26(3): 1-4, 8. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202203001.htm

    SHEN Q, ZHANG Q, WU T, et al. Clinical value of calcification scores of coronary artery CT angiography in evaluating coronary artery lesions and prognosis in patients with chronic angina pectoris[J]. Journal of Clinical Medicine in Practice, 2022, 26(3): 1-4, 8. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202203001.htm
    [20]
    马方伟, 张蕾, 陈首名, 等. 64层CCTA对冠心病患者冠状动脉狭窄的诊断价值[J]. 西部医学, 2023, 35(7): 1079-1082. https://www.cnki.com.cn/Article/CJFDTOTAL-XIBU202307027.htm

    MA F W, ZHANG L, CHEN S M, et al. Diagnostic value of 64-slice CCTA on coronary artery stenosis in patients with coronary artery disease[J]. Medical Journal of West China, 2023, 35(7): 1079-1082. https://www.cnki.com.cn/Article/CJFDTOTAL-XIBU202307027.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(6)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (67) PDF downloads(8) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return