Volume 22 Issue 4
Apr.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(4): 566-570
ZHAO Libo, CAI Weimeng, ZHAO Zhe, HE Zijun, FANG Fengfeng, LIU Lin, FAN Li. A meta-analysis of the prevalence of sarcopenia in patients with obstructive sleep apnea syndrome[J]. Chinese Journal of General Practice, 2024, 22(4): 566-570. doi: 10.16766/j.cnki.issn.1674-4152.003451
Citation: ZHAO Libo, CAI Weimeng, ZHAO Zhe, HE Zijun, FANG Fengfeng, LIU Lin, FAN Li. A meta-analysis of the prevalence of sarcopenia in patients with obstructive sleep apnea syndrome[J]. Chinese Journal of General Practice, 2024, 22(4): 566-570. doi: 10.16766/j.cnki.issn.1674-4152.003451
shu

A meta-analysis of the prevalence of sarcopenia in patients with obstructive sleep apnea syndrome

doi: 10.16766/j.cnki.issn.1674-4152.003451
  • 1.

    Graduate School of Medical School of Chinese PLA, Beijing 100853, China

Funds:

 23BJZ27

 22BJZ52

 LB20211A010013

  • Received Date: 2023-05-04
    Available Online: 2024-05-29
    Abstract
  •   Objective  To investigate the prevalence of sarcopenia in patients with obstructive sleep apnea syndrome (OSAS), to improve the awareness of the disease and aid in its prevention and treatment.  Methods  Relevant studies on OSAS and sarcopenia in patients were searched in the CNKI, Wanfang, PubMed, Web of Science and Cochrane databases from 1994 to January 28, 2023. Two researchers independently screened the literature, extracted data, and evaluated the quality of the included studies. Meta-analysis was performed using Stata 16.  Results  The analysis comprised nine studies, with a total of 2 815 patients diagnosed with OSAS, among whom 362 were diagnosed with sarcopenia. The meta-analysis revealed that the prevalence of sarcopenia in patients with OSAS was 31.58% (95% CI: 18.65% - 44.50%). The prevalence of sarcopenia in moderate to severe OSAS was 43.81% (95% CI: 12.66% - 74.95%), while the corresponding prevalence in mild to moderate to severe OSAS was 28.17% (95% CI: 13.80% - 42.54%). A subgroup analysis based on age revealed that the prevalence of sarcopenia was 17.89% (95% CI: 8.15% - 27.62%) in patients aged 40-60 years. The prevalence significantly increased in patients aged ≥ 60 years to 50.86% (95% CI: 42.46% - 59.25%).  Conclusion  The prevalence of sarcopenia was high in patients with OSAS, and this varied across different age groups. The prevalence of sarcopenia was higher in elderly patients aged 60 years or older. To effectively prevent and treat sarcopenia, it is important to focus on screening and treating sleep disorders. This will require increased attention to be paid to identifying and addressing sleep-related issues.

     

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