Volume 22 Issue 4
Apr.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(4): 571-573
LUO Song, WANG Xiaorui, MA Bo, QU Hongdang. Clinical effect observation of prednisone combined with sodium aescinate tablets in the treatment of facial neuritis[J]. Chinese Journal of General Practice, 2024, 22(4): 571-573. doi: 10.16766/j.cnki.issn.1674-4152.003452
Citation: LUO Song, WANG Xiaorui, MA Bo, QU Hongdang. Clinical effect observation of prednisone combined with sodium aescinate tablets in the treatment of facial neuritis[J]. Chinese Journal of General Practice, 2024, 22(4): 571-573. doi: 10.16766/j.cnki.issn.1674-4152.003452
shu

Clinical effect observation of prednisone combined with sodium aescinate tablets in the treatment of facial neuritis

doi: 10.16766/j.cnki.issn.1674-4152.003452

  • Department of Neurology, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China

Funds:

 202304295107020076

 2022AH051480

 2022

  • Received Date: 2023-04-13
    Available Online: 2024-05-29
    Abstract
  •   Objective  To explore the clinical efficacy of combining sodium aescinate tablets with prednisone in the treatment of facial neuritis and to explore the clinical value of this scheme in treating facial neuritis.  Methods  This study enrolled 60 patients with facial neuropathy from January 2020 to December 2022 at the Department of Neurology, the First Affiliated Hospital of Bengbu Medical University. The patients were randomly divided into two groups using a random number table method: the control group (n=30) received conventional treatment, while the observation group (n=30) received conventional therapy along with the addition of sodium aescinate tablets. After a 30-day treatment period, the clinical effects were assessed by comparing neural function scores, House-Brackman (H-B) rating, and record adverse events between the two groups.  Results  Following clinical treatment, the observation group showed 9 patients achieving complete recovery (30.0%), 10 patients with significant improvement (33.3%), 9 were effective (30.0%), and 2 patients with no improvement (6.7%). In the control group, 7 patients achieved complete recovery (23.3%), 9 patients showed significant improvement (30.0%), 6 patients had moderate improvement (20.0%), and 8 patients showed no improvement (26.7%). The difference in total effective rate between the two groups was statistically significant (P < 0.05). The mean score of the patients in the observation group was 69.33±14.41, which was higher than that in the control group (61.63±9.45) after treatment, with a statistical difference (P < 0.05). There was no significant difference in H-B grade between the observation group and the control group (P>0.05). Additionally, no significant difference in adverse events was observed between the observation group and the control group (P>0.05).  Conclusion  The combination of sodium aescinate tablets and propionate promotes improved facial neuropathic function and enhances safety.

     

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