Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia

KANG Niansong; HUANG Jian; QIAN Rong; GU Hongping; HAN Xufeng; SU Wentao

doi:10.16766/j.cnki.issn.1674-4152.003459

Volume 22 Issue 4

Apr. 2024

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Article Navigation > Chinese Journal of General Practice > 2024 > 22(4): 597-600

KANG Niansong, HUANG Jian, QIAN Rong, GU Hongping, HAN Xufeng, SU Wentao. Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia[J]. Chinese Journal of General Practice, 2024, 22(4): 597-600. doi: 10.16766/j.cnki.issn.1674-4152.003459

Citation:

KANG Niansong, HUANG Jian, QIAN Rong, GU Hongping, HAN Xufeng, SU Wentao. Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia[J]. Chinese Journal of General Practice, 2024, 22(4): 597-600. doi: 10.16766/j.cnki.issn.1674-4152.003459

Citation:

KANG Niansong, HUANG Jian, QIAN Rong, GU Hongping, HAN Xufeng, SU Wentao. Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia[J]. Chinese Journal of General Practice, 2024, 22(4): 597-600. doi: 10.16766/j.cnki.issn.1674-4152.003459

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Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia

doi: 10.16766/j.cnki.issn.1674-4152.003459

1.
Department of Treatment of Disease Department, Yuyao Hospital of Traditional Chinese Medicine, Yuyao, Zhejiang 315400, China

Funds:

浙中医药[2021]22号

2020ZYC-B0

Received Date: 2023-10-31
Available Online: 2024-05-29

Abstract

Abstract

Objective To explore the clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules on patients with functional dyspepsia and their influence on serum pepsinogen and gastrin-17 levels. Methods Using a random number table, 128 patients diagnosed with functional dyspepsia at Yuyao Hospital of Traditional Chinese Medicine between October 2021 and December 2022 were divided into two groups: Weifuchun group and Mosapride group, eaching consisting of 64 cases. The mosapride group was given a combination of omeprazole and Mosapride tablets, while the Weifuchun group was given a combination of omeprazole and Weifuchun tablets. After 4 weeks of continuous treatment, the therapeutic effect, serum pepsinogen, and gastrin-17 levels were compared between the two groups. Results After 4 weeks of treatment, the Weifuchun group demonstrated a higher total effective rate (87.50%, 56/64) compared to the Mosapride group (71.88%, 46/64), with a statistically significant difference (χ²=4.827, P < 0.05). The Weifuchun group also exhibited higher levels of pepsinogen Ⅰ [(113.20±10.21) μg/L] compared to the Moxapride group [(98.26±9.64) μg/L, P < 0.05]. Moreover, the Weifuchun group showed lower levels of pepsinogen Ⅱ[(17.21±2.58) μg/L] and gastrin-17 [(15.31±2.09) pmol/L] compared to the Mosapride group [(20.31±3.11) μg/L, (18.22±2.67) pmol/L, P < 0.05]. Conclusion The combination of Weifuchun tablets and omeprazole enteric-coated capsules significantly improves the clinical symptoms of patients with functional dyspepsia. It effectively corrects abnormal levels of serum pepsinogen and gastrin-17, leading to improved prognosis and enhanced quality of life for patients.
- Functional dyspepsia,
- Weifuchun tablets,
- Serum pepsinogen,
- Omeprazole,
- Gastrin-17

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Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia

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Clinical effect of Weifuchun tablets combined with omeprazole enteric-coated capsules in the treatment of functional dyspepsia

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