Volume 22 Issue 4
Apr.  2024
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LUO Qinyin, TAO Binwen, GAN Li, HUANG Lizhu. Clinical effectiveness observation of left ventricular pressure strain loop technique for evaluating early changes in myocardial function among patients with hyperthyroidism[J]. Chinese Journal of General Practice, 2024, 22(4): 642-645. doi: 10.16766/j.cnki.issn.1674-4152.003470
Citation: LUO Qinyin, TAO Binwen, GAN Li, HUANG Lizhu. Clinical effectiveness observation of left ventricular pressure strain loop technique for evaluating early changes in myocardial function among patients with hyperthyroidism[J]. Chinese Journal of General Practice, 2024, 22(4): 642-645. doi: 10.16766/j.cnki.issn.1674-4152.003470
shu

Clinical effectiveness observation of left ventricular pressure strain loop technique for evaluating early changes in myocardial function among patients with hyperthyroidism

doi: 10.16766/j.cnki.issn.1674-4152.003470

  • Department of Ultrasound, Baise People' s Hospital, Baise, Guangxi 533000, China

Funds:

 20211735

  • Received Date: 2023-11-07
    Available Online: 2024-05-29
    Abstract
  •   Objective  The objective is to enable early assessment and intervention of hyperthyroidism heart disease, improve the overall prognosis of hyperthyroidism patients, and explore the clinical effectiveness of utilizing left ventricular pressure strain loop (LVPSL) technology for monitoring early changes in myocardial function among hyperthyroidism patients.  Methods  A retrospective study was conducted at Baise People ' s Hospital from January 2021 to August 2023. A total of 100 patients with hyperthyroidism and 100 healthy subjects were selected as research participants. All subjects underwent routine echocardiography and LVPSL analysis. The study compared the differences in conventional echocardiographic and LVPSL indicators between hyperthyroidism patients and healthy subjects, and analyzed the correlation between LVPSL indicator values and serum thyroid hormone levels in hyperthyroidism patients.  Results  There was no statistically significant differences in conventional echocardiography indicators such as LAD, LVPWT, IVST, LVEDD, LVESD, and LVEF between patients with hyperthyroidism and the control group (P>0.05). However, hyperthyroidism patients exhibited significantly lower values of GLS (absolute value), GWI, GCW, and GWE compared to healthy subjects, while the GWW detection value was significantly higher (P < 0.001). Furthermore, GLS (absolute value), GWI, GCW, and GWE showed negative correlations with serum FT3 and FT4 levels (P < 0.001), but positive corrections with serum TSH levels (P < 0.001). On the other hand, GWW demonstrated positive correlations with serum FT3 and FT4 levels (r=0.526, 0.547; P < 0.001), while showing a negative correlation with serum TSH levels (r=-0.641, P < 0.001).  Conclusion  LVPSL technology can effectively identify early myocardial functional changes in hyperthyroidism patients that are not detectable through conventional echocardiography. It serves as a valuable tool for evaluating myocardial injury in hyperthyroidism patients and predicting the onset of early hyperthyroidism heart disease.

     

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    • References(19)
  • [1]
    龚文倩, 田昀灵, 史雨荣, 等. 药物与131I治疗甲状腺功能亢进的临床安全性和医疗经济性对比研究[J]. 兰州大学学报(医学版), 2022, 48(7): 45-49, 56. https://www.cnki.com.cn/Article/CJFDTOTAL-LZYX202207009.htm

    GONG W Q, TIAN Y L, SHI Y R, et al. Comparative study of clinical safety and medical economy between drugs and 131I in the treatment of hyperthyroidism[J]. Journal of Lanzhou University(Medical Sciences), 2022, 48(7): 45-49, 56. https://www.cnki.com.cn/Article/CJFDTOTAL-LZYX202207009.htm
    [2]
    朱正雷. 丙硫氧嘧啶联合碳酸锂治疗甲状腺功能亢进症的临床疗效及对甲状腺功能的影响[J]. 临床合理用药, 2023, 16(21): 101-103. https://www.cnki.com.cn/Article/CJFDTOTAL-PLHY202321029.htm

    ZHU Z L. The clinical efficacy and impact on thyroid function of the combination of propylthiouracil and lithium carbonate in the treatment of hyperthyroidism[J]. Chinese Journal of Clinical Rational Drug Use, 2023, 16(21): 101-103. https://www.cnki.com.cn/Article/CJFDTOTAL-PLHY202321029.htm
    [3]
    SOHN S Y, LEE E, LEE M K, et al. The association of overt and subclinical hyperthyroidism with the risk of cardiovascular events and cardiovascular mortality: meta-analysis and systematic review of cohort studies[J]. Endocrinol Metab (Seoul), 2020, 35(4): 786-800. doi: 10.3803/EnM.2020.728
    [4]
    IVANOV S I, ALEKHIN M N. Myocardial work in assessment of left ventricular systolic function[J]. Kardiologiia, 2020, 60(3): 80-88. doi: 10.18087/cardio.2020.3.n925
    [5]
    张莉, 尹立雪, 王锐. 超声新技术评估甲状腺功能亢进患者左心室心肌功能研究进展[J]. 实用医院临床杂志, 2022, 19(4): 214-217. https://www.cnki.com.cn/Article/CJFDTOTAL-YYLC202204060.htm

    ZHANG L, YIN L X, WANG R. Progress of new ultrasound evaluation of left ventricular myocardial function in patients with hyperthyroidism[J]. Practical Journal of Clinical Medicine, 2022, 19(4): 214-217. https://www.cnki.com.cn/Article/CJFDTOTAL-YYLC202204060.htm
    [6]
    中华医学会内分泌分会. 中国甲状腺疾病诊治指南: 甲状腺功能亢进症[J]. 中华内科杂志, 2007, 46(10): 876-882. https://www.cnki.com.cn/Article/CJFDTOTAL-HJYY202402043.htm

    Endocrine Branch of the Chinese Medical Association. Chinese guidelines for diagnosis and treatment of thyroid diseases : hyperthyroidism[J]. Chinese Journal of Internal Medicine, 2007, 46(10): 876-882. https://www.cnki.com.cn/Article/CJFDTOTAL-HJYY202402043.htm
    [7]
    MITCHELL C, RAHKO P S, BLAUWET L A, et al. Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the american society of echocardiography[J]. J Am Soc Echocardiogr, 2019, 32(1): 1-64. doi: 10.1016/j.echo.2018.06.004
    [8]
    郝晓东, 刘靖美, 崔莹. 甲状腺功能亢进并发甲亢性心脏病的危险因素分析[J]. 实用妇科内分泌电子杂志, 2020, 7(18): 151-152. https://www.cnki.com.cn/Article/CJFDTOTAL-FKDZ202018106.htm

    HAO X D, LIU Q M, CUI Y. Analysis of risk factors of hyperthyroidism complicated with hyperthyroidism heart disease[J]. Electronic Journal of Practical Gynecological Endocrinology, 2020, 7(18): 151-152. https://www.cnki.com.cn/Article/CJFDTOTAL-FKDZ202018106.htm
    [9]
    MANGANARO R, MARCHETTA S, DULGHERU R, et al. Correlation between non-invasive myocardial work indices and main parameters of systolic and diastolic function: results from the EACVI NORRE study[J]. Eur Heart J Cardiovasc Imaging, 2020, 21(5): 533-541. doi: 10.1093/ehjci/jez203
    [10]
    李庞敏, 刘立栋, 王亚妮, 等. 心肌酶水平变化对甲状腺功能亢进性心脏病患者的诊断价值[J]. 中国医药科学, 2022, 12(14): 146-149, 156. https://www.cnki.com.cn/Article/CJFDTOTAL-GYKX202214037.htm

    LI P M, LIU L D, WANG Y N, et al. Diagnostic value of the changes in cardiac enzyme levels of patients with hyperthyroid heart disease[J]. China Medicine And Pharmacy, 2022, 12(14): 146-149, 156. https://www.cnki.com.cn/Article/CJFDTOTAL-GYKX202214037.htm
    [11]
    石楠楠, 元玲玲, 马天舒. 甲状腺功能亢进型心脏病患者血清甲状腺过氧化物酶抗体、甲状腺球蛋白抗体变化的意义研究[J]. 中国医药指南, 2021, 19(10): 107-108. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK202110048.htm

    SHI N N, YUAN L L, MA T S. Significance of Changes of Serum Thyroid Peroxidase Antibody and Thyroglobulin Antibody in Patients with Hyperthyroidism Heart Disease[J]. Guide of China Medicine, 2021, 19(10): 107-108. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXK202110048.htm
    [12]
    陈静婉, 杨道玲. 经食道超声心动图评价房颤患者左心耳容积和功能改变的临床意义[J]. 中华全科医学, 2020, 18(3): 408-411. doi: 10.16766/j.cnki.issn.1674-4152.001259

    CHEN J W, YANG D L. Clinical significance of transesophageal echocardiography in the evaluation of left auricular volume and function in patients with atrial fibrillation[J]. Chinese Journal of General Practice, 2020, 18(3): 408-411. doi: 10.16766/j.cnki.issn.1674-4152.001259
    [13]
    杨欋力, 孙立娟, 刘亚丽, 等. 基于斑点追踪技术测定二尖瓣环位移评估甲亢性心脏病左心室收缩功能改变的临床研究[J]. 中国急救复苏与灾害医学杂志, 2023, 18(2): 145-148, 169. https://www.cnki.com.cn/Article/CJFDTOTAL-YTFS202302002.htm

    YANG Q L, SUN L J, LIU Y L, et al. Clinical study on the measurement of mitral valve annulus displacement based on speckle tracking technology to evaluate the changes of left ventricular systolic function in hyperthyroid heart disease[J]. China Journal of Emergency Resuscitation and Disaster Medicine, 2023, 18(2): 145-148, 169. https://www.cnki.com.cn/Article/CJFDTOTAL-YTFS202302002.htm
    [14]
    胡卫中, 甘甜, 何婧, 等. 超声心动图及血清NT-proBNP检测对甲亢性心脏病的早期诊断价值[J]. 大连医科大学学报, 2021, 43(6): 505-508. https://www.cnki.com.cn/Article/CJFDTOTAL-DLYK202106007.htm

    HU W Z, GAN T, HE J, et al. Early diagnosis value of echocardiography and NT-proBNP in hyperthyroid heart disease[J]. Journal of Dalian Medical University, 2021, 43(6): 505-508. https://www.cnki.com.cn/Article/CJFDTOTAL-DLYK202106007.htm
    [15]
    唐莎, 李华, 宋磊, 等. 左室压力-应变环评价不同剂量蒽环类药物对乳腺癌患者左室心肌的做功[J]. 心脏杂志, 2021, 33(6): 637-641. https://www.cnki.com.cn/Article/CJFDTOTAL-XGNZ202106027.htm

    TANG S, LI H, SONG L, et al. Evaluation of left ventricular myocardial work in breast cancer patients treated with different doses of anthracycline by left ventricular pressure-strain loop[J]. Chinese Heart Journal, 2021, 33(6): 637-641. https://www.cnki.com.cn/Article/CJFDTOTAL-XGNZ202106027.htm
    [16]
    黄梅凤, 袁新春, 曾曦, 等. 左心室压力-应变环评价2型糖尿病合并高血压患者的心肌做功[J]. 中国超声医学杂志, 2023, 39(4): 405-409. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCY202304012.htm

    HUANG M F, YUAN X C, ZENG X, et al. Evaluation of Myocardial Work in Patients with Type 2 Diabetes Mellitus and Hypertension Using Left Ventricular Pressure-Strain Loops[J]. Chinese Journal of Ultrasound in Medicine, 2023, 39(4): 405-409. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCY202304012.htm
    [17]
    陈碧华, 黄定伟, 许厚本. 无创左心室压力-应变环定量评价冠心病患者冠状动脉狭窄[J]. 心脏杂志, 2023, 35(2): 191-195. https://www.cnki.com.cn/Article/CJFDTOTAL-XGNZ202302027.htm

    CHEN B H, HUANG D W, XU H B. Quantitative evaluation of coronary artery stenosis in patients with coronary atherosclerotic heart disease by left ventricular pressure-strain loops[J]. Chinese Heart Journal, 2023, 35(2): 191-195. https://www.cnki.com.cn/Article/CJFDTOTAL-XGNZ202302027.htm
    [18]
    任梅, 尹立雪, 朱静, 等. 类风湿关节炎左心室收缩功能的超声压力-应变环评价[J]. 中国临床医学影像杂志, 2022, 33(10): 704-709. https://www.cnki.com.cn/Article/CJFDTOTAL-LYYX202210005.htm

    REN M, YIN L X, ZHU J, et al. Evaluation of left ventricular systolic function by echocardiographic pressure-strain loops in patients with rheumatoid arthritis[J]. Journal of China Clinic Medical Imaging, 2022, 33(10): 704-709. https://www.cnki.com.cn/Article/CJFDTOTAL-LYYX202210005.htm
    [19]
    司雪霏, 李天亮, 胡新玲, 等. 超声左心室压力-应变环评价心力衰竭患者心脏再同步化治疗前左心室心肌做功的价值[J]. 中国医学影像学杂志, 2022, 30(10): 1008-1012. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYZ202210006.htm

    SI X F, LI T L, HU X L, et al. Assessment of Ventricular Myocardial Work in Heart Failure Patients Before Cardiac Resynchronization Therapy by Echocardiographic Pressure-Strain Loop[J]. Chinese Journal of Medical Imaging, 2022, 30(10): 1008-1012. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYZ202210006.htm
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