Volume 22 Issue 4
Apr.  2024
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LUO Qinyin, TAO Binwen, GAN Li, HUANG Lizhu. Clinical effectiveness observation of left ventricular pressure strain loop technique for evaluating early changes in myocardial function among patients with hyperthyroidism[J]. Chinese Journal of General Practice, 2024, 22(4): 642-645. doi: 10.16766/j.cnki.issn.1674-4152.003470
Citation: LUO Qinyin, TAO Binwen, GAN Li, HUANG Lizhu. Clinical effectiveness observation of left ventricular pressure strain loop technique for evaluating early changes in myocardial function among patients with hyperthyroidism[J]. Chinese Journal of General Practice, 2024, 22(4): 642-645. doi: 10.16766/j.cnki.issn.1674-4152.003470
shu

Clinical effectiveness observation of left ventricular pressure strain loop technique for evaluating early changes in myocardial function among patients with hyperthyroidism

doi: 10.16766/j.cnki.issn.1674-4152.003470

  • Department of Ultrasound, Baise People' s Hospital, Baise, Guangxi 533000, China

Funds:

 20211735

  • Received Date: 2023-11-07
    Available Online: 2024-05-29
    Abstract
  •   Objective  The objective is to enable early assessment and intervention of hyperthyroidism heart disease, improve the overall prognosis of hyperthyroidism patients, and explore the clinical effectiveness of utilizing left ventricular pressure strain loop (LVPSL) technology for monitoring early changes in myocardial function among hyperthyroidism patients.  Methods  A retrospective study was conducted at Baise People ' s Hospital from January 2021 to August 2023. A total of 100 patients with hyperthyroidism and 100 healthy subjects were selected as research participants. All subjects underwent routine echocardiography and LVPSL analysis. The study compared the differences in conventional echocardiographic and LVPSL indicators between hyperthyroidism patients and healthy subjects, and analyzed the correlation between LVPSL indicator values and serum thyroid hormone levels in hyperthyroidism patients.  Results  There was no statistically significant differences in conventional echocardiography indicators such as LAD, LVPWT, IVST, LVEDD, LVESD, and LVEF between patients with hyperthyroidism and the control group (P>0.05). However, hyperthyroidism patients exhibited significantly lower values of GLS (absolute value), GWI, GCW, and GWE compared to healthy subjects, while the GWW detection value was significantly higher (P < 0.001). Furthermore, GLS (absolute value), GWI, GCW, and GWE showed negative correlations with serum FT3 and FT4 levels (P < 0.001), but positive corrections with serum TSH levels (P < 0.001). On the other hand, GWW demonstrated positive correlations with serum FT3 and FT4 levels (r=0.526, 0.547; P < 0.001), while showing a negative correlation with serum TSH levels (r=-0.641, P < 0.001).  Conclusion  LVPSL technology can effectively identify early myocardial functional changes in hyperthyroidism patients that are not detectable through conventional echocardiography. It serves as a valuable tool for evaluating myocardial injury in hyperthyroidism patients and predicting the onset of early hyperthyroidism heart disease.

     

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