Volume 22 Issue 4
Apr.  2024
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CONG Riping, ZHANG Yujian, GAO Binxue, ZHANG Jianbo, XU Lujia, DIAO Yingli, WANG Wei, TANG Kuanxiao. Research progress of the effect of glycemic control on the prognosis of diabetes with corona virus disease 2019[J]. Chinese Journal of General Practice, 2024, 22(4): 656-660. doi: 10.16766/j.cnki.issn.1674-4152.003473
Citation: CONG Riping, ZHANG Yujian, GAO Binxue, ZHANG Jianbo, XU Lujia, DIAO Yingli, WANG Wei, TANG Kuanxiao. Research progress of the effect of glycemic control on the prognosis of diabetes with corona virus disease 2019[J]. Chinese Journal of General Practice, 2024, 22(4): 656-660. doi: 10.16766/j.cnki.issn.1674-4152.003473

Research progress of the effect of glycemic control on the prognosis of diabetes with corona virus disease 2019

doi: 10.16766/j.cnki.issn.1674-4152.003473
  • Received Date: 2024-01-21
    Available Online: 2024-05-29
  • Corona virus disease 2019 (COVID-19) is an acute infectious disease caused by severe acute respiratory syndrome coronavirus 2 with high incidence, strong infectivity and rapid state change. The characteristics of type 2 diabetes mellitus (T2DM) with COVID-19 are uncontrollable, many complications, high critical rate and mortality. Blood glucose variability is one of the main reasons. Currently, there is no accepted time in range (TIR), and TIR is closely associated with prognosis. Glucose variability parameters are independent risk factors for predicting mortality in critical patients. The monitoring of glucose variability is important to realize the fine management of blood glucose. This article reviews the research progress of the effect of glycemic control on the prognosis of T2DM with COVID-19. The main contents include the epidemiological status, major pathophysiological mechanisms (e.g., cytokine release syndrome, abnormal expression of angiotensin-converting enzyme 2, etc.), glycemic control goals, and scientific management of patients. This review provides a theoretical reference for optimizing the diagnosis and treatment strategy, improving the prognosis, and reducing the incidence of complications and mortality.

     

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