Volume 22 Issue 5
May  2024
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ZHOU Wujie, JIN Yingying, LUO Guogang. Correlation between preoperative serum osmotic pressure level and hospitalization time and complication risk of elderly patients with femoral neck fracture[J]. Chinese Journal of General Practice, 2024, 22(5): 791-794. doi: 10.16766/j.cnki.issn.1674-4152.003504
Citation: ZHOU Wujie, JIN Yingying, LUO Guogang. Correlation between preoperative serum osmotic pressure level and hospitalization time and complication risk of elderly patients with femoral neck fracture[J]. Chinese Journal of General Practice, 2024, 22(5): 791-794. doi: 10.16766/j.cnki.issn.1674-4152.003504

Correlation between preoperative serum osmotic pressure level and hospitalization time and complication risk of elderly patients with femoral neck fracture

doi: 10.16766/j.cnki.issn.1674-4152.003504
Funds:

 2021ZB275

 Y20210440

  • Received Date: 2023-12-10
  •   Objective  To analyze the preoperative serum osmotic pressure level of elderly patients with femoral neck fracture, and to explore the relationship between its level and hospitalization time and the risk of complications.  Methods  A total of 120 patients with femoral neck fracture who were treated in Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine from January 2020 to December 2021 were selected as the research object. According to the preoperative serum osmotic pressure level of patients, patients were divided into high-level group and low-level group. The clinical data of patients were collected and followed up for one year to record all-cause deaths. Spearman correlation was used to analyze the correlation between preoperative serum osmotic pressure level and hospitalization time and complications, and Cox regression was used to analyze the influencing factors of survival rate of elderly patients with femoral neck fracture.  Results  Forty-one patients were included in the high-level group and 79 in the low-level group. Preoperative serum osmotic pressure level was positively correlated with MPI score (r=0.501), hospital stay (r=0.496) and postoperative complications (r=0.383), P<0.05. Cox regression analysis showed that gender (HR=17.404), serum osmolality level (HR=1.136), MPI score (HR=1.294) and GPS score (HR=0.114) were all influencing factors for postoperative death in elderly patients with femoral neck. Cox regression analysis after adjusting for gender, MPI score and GPS score found that preoperative serum osmolality level (HR=1.071) was an independent determinant of postoperative death in elderly femoral neck patients (P<0.05).  Conclusion  The hospitalization time and complications of elderly patients with femoral neck fracture are related to the preoperative serum osmotic pressure level and the degree of weakness. Preoperative examination of serum osmotic pressure level is helpful for more adequate perioperative fluid management to reduce the risk of postoperative death.

     

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