Volume 22 Issue 5
May  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(5): 859-862
ZHANG Rumeng, WU Ming, XU Peng, CHEN Yuhua. Observation on the curative effect of acupuncture combined with Zusanli acupoint injection in the treatment of persistent hiccups[J]. Chinese Journal of General Practice, 2024, 22(5): 859-862. doi: 10.16766/j.cnki.issn.1674-4152.003520
Citation: ZHANG Rumeng, WU Ming, XU Peng, CHEN Yuhua. Observation on the curative effect of acupuncture combined with Zusanli acupoint injection in the treatment of persistent hiccups[J]. Chinese Journal of General Practice, 2024, 22(5): 859-862. doi: 10.16766/j.cnki.issn.1674-4152.003520
shu

Observation on the curative effect of acupuncture combined with Zusanli acupoint injection in the treatment of persistent hiccups

doi: 10.16766/j.cnki.issn.1674-4152.003520

  • Department of the Rehabilitation Medicine, the First Affiliated Hospital of the University of Science and Technology of China, Hefei, Anhui 230001, China

Funds:

 2022e07020021

 MAI2022C006

  • Received Date: 2023-10-19
    Available Online: 2024-07-20
    Abstract
  •   Objective  To explore the efficacy and safety of acupuncture combined with Zusanli acupoint injection of metoclopramide in the treatment of persistent hiccups, and to compare the differences in the therapeutic effects of this method on central and peripheral persistent hiccups.  Methods  A total of 48 patients with persistent hiccups were selected from the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital) from July 2018 to August 2022, including 36 patients in the central treatment group and 12 patients in the peripheral treatment group. The two groups were treated with acupuncture at Cuanzhu, Danzhong, Zhongwan, Geshu, Neiguan, Zusanli and other points, and the needles were retained for 30 min. After taking the needle, 1ml metoclopramide hydrochloride was injected into the right Zusanli (ST36), and the same dose was injected into the left Zusanli 4-6 hours later, for a total of 3 treatments. Hiccups assessment instrument (HAI) was used to assess the severity of hiccups in the two groups after each treatment and after the end of the treatment. The total effective rate of the two groups was compared after treatment. The total effective rate of the two groups was compared after treatment.  Results  After treatment, there were statistically significant differences in HAI scores between before treatment and after the first, second and third treatment, between after the first treatment and after the second and third treatment, and between after the second and third treatment in two groups (all P<0.05). After the first, second and third treatment, the HAI scores of the peripheral treatment group were significantly lower than that of the central treatment group (4.25±2.60 vs. 6.69±2.07, 1.96±1.75 vs. 3.64±3.08, 0.45±0.36 vs. 2.18±2.06, P<0.05). The total effective rate of the peripheral treatment group was significantly higher than that of the central treatment group (91.67% vs. 52.78%, χ2=4.267, P=0.039).  Conclusion  The method of acupuncture combined with Zusanli acupoint injection is effective for persistent hiccups caused by both central and peripheral causes, and the therapeutic effect is better for peripheral causes.

     

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    • References(28)
  • [1]
    JATOI A. Evaluating and palliating hiccups[J]. BMJ Support Palliat Care, 2022, 12(4): 475-478. doi: 10.1136/bmjspcare-2022-003676
    [2]
    STEGER M, SCHNEEMANN M, FOX M. Systemic review: the pathogenesis and pharmacological treatment of hiccups[J]. Aliment Pharmacol Ther, 2015, 42(9): 1037-1050. doi: 10.1111/apt.13374
    [3]
    KOHSE E K, HOLLMANN M W, BARDENHEUER H J, et al. Chronic hiccups: an underestimated problem[J]. Anesth Analg, 2017, 125(4): 1169-1183. doi: 10.1213/ANE.0000000000002289
    [4]
    CHANG F Y, LU C L. Hiccup: mystery, nature and treatment[J]. J Neurogastroenterol Motil, 2012, 18(2): 123-130. doi: 10.5056/jnm.2012.18.2.123
    [5]
    EROGLU O. The effect of gender differences in protracted hiccups[J]. Niger J Clin Pract, 2018, 21(10): 1356-1360. doi: 10.4103/njcp.njcp_101_18
    [6]
    POLITO N B, FELLOWS S E. Pharmacologic interventions for intractable and persistent hiccups: a systematic review[J]. J Emerg Med, 2017, 53(4): 540-549. doi: 10.1016/j.jemermed.2017.05.033
    [7]
    ROUSE S, WODZZIAK M. Intractable hiccups[J]. Curr Neurol Neurosci Rep, 2018, 18(8): 51. DOI: 10.1007/s11910-018-0856-0.
    [8]
    XU J, QU Y, YUE Y, et al. Treatment of persistent hiccups after arthroplasty: effects of acupuncture at PC6, CV12 and ST36[J]. Acupunct Med, 2019, 37(1): 72-76. doi: 10.1136/acupmed-2016-011304
    [9]
    陈幼楠, 郭长青, 刘清国. 《针灸技术操作规范第6部分: 穴位注射》研制及应用的若干问题探讨[J]. 中国针灸, 2009, 29(7): 581-586. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZE200907027.htm

    CHEN Y N, GUO C Q, LIU Q G. Technical specification for acupuncture and moxibustion-Part 6 : discussion on the development and application of acupoint injection[J]. Chinese Acupuncture,, 2009, 29(7): 581-586. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZE200907027.htm
    [10]
    黄田, 彭梓, 周建伟. 近十年针灸治疗顽固性呃逆研究进展[J]. 中国民族民间医药, 2021, 30(16): 58-60. https://www.cnki.com.cn/Article/CJFDTOTAL-MZMJ202116017.htm

    HUANG T, PENG Z, ZHOU J W. Research progress of acupuncture and moxibustion in the treatment of intractable hiccup in recent ten years[J]. Chinese Folk Medicine, 2021, 30(16): 58-60. https://www.cnki.com.cn/Article/CJFDTOTAL-MZMJ202116017.htm
    [11]
    李凤梅, 倪夕秀, 李晓, 等. 针灸治疗呃逆的系统评价再评价[J]. 按摩与康复医学, 2020, 11(23): 5-9. https://www.cnki.com.cn/Article/CJFDTOTAL-AMYD202023003.htm

    LI F M, NI X X, LI X, et al. Systematic review of acupuncture for hiccups reevaluation[J]. Massage and Rehabilitation Medicine, 2020, 11(23): 5-9. https://www.cnki.com.cn/Article/CJFDTOTAL-AMYD202023003.htm
    [12]
    REICHENBACH Z W, PIECH G M, MALIK Z. Chronic hiccups[J]. Curr Treat Options Gastroenterol, 2020, 18(1): 43-59. doi: 10.1007/s11938-020-00273-3
    [13]
    LEE A R, CHO Y W, LEE J M, et al. Treatment of persistent postoperative hiccups with stellate ganglion block: three case reports[J]. Medicine (Baltimore), 2018, 97(48): e13370. DOI: 10.1097/MD.0000000000013370.
    [14]
    DE VLOO P, DALLAPIAZZA R F, LEE D J, et al. Long-term relief of intractable hiccups with vagal nerve stimulation[J]. Brain Stimul, 2018, 11(6): 1385-1387. doi: 10.1016/j.brs.2018.08.002
    [15]
    JEON Y S, KEARNEY A M, BAKER P G. Management of hiccups in palliative care patients[J]. BMJ Support Palliat Care, 2018, 8(1): 1-6. doi: 10.1136/bmjspcare-2016-001264
    [16]
    QUIROGA J B, GARCIA J U, GUEDES J B. Hiccups: a common problem with some unusual causes and cures[J]. Br J Gen Pract, 2016, 66(652): 584-586. doi: 10.3399/bjgp16X687913
    [17]
    NAUSHEEN F, MOHSIN H, LAKHAN S E. Neurotransmitters in hiccups[J]. Springerplus, 2016, 5(1): 1-7. doi: 10.1186/s40064-015-1659-2
    [18]
    MOONEN V, RAAF M, DEPIERREUX F, et al. Hiccups, not always unremarkable[J]. Rev Med Liege, 2022, 77(3): 161-166.
    [19]
    SCHIFF E, OLIVEN A, ODEH M, et al. Acupuncture therapy for persistent hiccups[J]. Am J Med Sci, 2002, 323(3): 166-168. doi: 10.1097/00000441-200203000-00010
    [20]
    LIU F C, CHEN C A, YANG S S, et al. Acupuncture therapy rapidly terminates intractable hiccups complicating acute myocardial infarction[J]. South Med J, 2005, 98(3): 385-387. doi: 10.1097/01.SMJ.0000146619.74871.37
    [21]
    杨光, 李莎, 郑曼. 电针复合耳穴埋籽对妇科开腹手术患者术后恶心呕吐的影响[J]. 中华全科医学, 2021, 19(11): 1929-1931, 1959. doi: 10.16766/j.cnki.issn.1674-4152.002203

    YANG G, LI S, ZHENG M. Effect of electroacupuncture combined with auricular seed embedding on postoperative nausea and vomiting in patients undergoing gynecological laparotomy[J]. Chinese Journal of General Practice, 2021, 19(11): 1929-1931, 1959. doi: 10.16766/j.cnki.issn.1674-4152.002203
    [22]
    SOHN Y Z, CONRAD L J, KATZ R L. Hiccup and ephedrine[J]. Can Anaesth Soc J, 1978, 25(5): 431-432. doi: 10.1007/BF03006576
    [23]
    马爱勤, 王会丽, 王靖霞. 穴位埋针治疗脑病并发呃逆21例[J]. 中国民间疗法, 2013, 21(8): 19. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL201308021.htm

    MA A Q, WANG H L, WANG J X. Acupuncture treatment for cerebral disorders induced hiccup in 21 cases[J]. Chinese Folk Therapy, 2013, 21(8): 19. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL201308021.htm
    [24]
    WANG D, ZI C, ZHANG B, et al. Effectiveness and safety of metoclopramide in treatment of intractable hiccup: a protocol of systematic review and meta-analysis[J]. BMJ Open, 2022, 12(10): e059887. DOI: 10.1136/bmjopen-2021-059887.
    [25]
    梅丽霞. 足三里穴位注射甲氧氯普胺结合攒竹穴指按治疗中风后呃逆疗效观察[J]. 实用中医药杂志, 2020, 36(10): 1300-1301. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYAO202010037.htm

    MEI L X. Observation on the curative effect of acupoint injection of metoclopramide at Zusanli combined with finger pressing at Cuanzhu point on post-stroke hiccups[J]. Journal of Practical Chinese Medicine, 2020, 36(10): 1300-1301. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYAO202010037.htm
    [26]
    欧阳观, 徐桂菊. 穴位注射甲氧氯普胺联合针刺治疗顽固性呃逆患者的效果[J]. 中国民康医学, 2021, 33(12): 61-63. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMYX202112025.htm

    OUYANG G, XU G J. Effect of Acupoint injection of metoclopramide combined with acupuncture in the treatment of refractory hiccup patients[J]. Medical Journal of Chinese People' s Health, 2021, 33(12): 61-63. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMYX202112025.htm
    [27]
    王培颖. 足三里穴位注射胃复安治疗急性胃肠炎致呕吐的疗效观察[J]. 实用中医内科杂志, 2019, 33(12): 67-70. https://www.cnki.com.cn/Article/CJFDTOTAL-SYZY201912024.htm

    WANG P Y. Clinical observation on Zusanli Acupoint injection of metoclopramide on vomiting due to acute gastroenteritis[J]. Journal of Practical Traditional Chinese Internal Medicine, 2019, 33(12): 67-70. https://www.cnki.com.cn/Article/CJFDTOTAL-SYZY201912024.htm
    [28]
    杨兰兰. 脑卒中后顽固性呃逆给予针灸治疗的临床研究[J]. 中外医学研究, 2019, 17(8): 45-46. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY201908021.htm

    YANG L L. Clinical study of acupuncture treatment for intractable hiccup after stroke[J]. Chinese And Foreign Medical Research, 2019, 17(8): 45-46. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY201908021.htm
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