Volume 22 Issue 5
May  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(5): 882-886
ZHU Yunxia, YANG Can, WANG Hemei, CHEN Zengli, FEI Zhenzhen. Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone[J]. Chinese Journal of General Practice, 2024, 22(5): 882-886. doi: 10.16766/j.cnki.issn.1674-4152.003526
Citation: ZHU Yunxia, YANG Can, WANG Hemei, CHEN Zengli, FEI Zhenzhen. Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone[J]. Chinese Journal of General Practice, 2024, 22(5): 882-886. doi: 10.16766/j.cnki.issn.1674-4152.003526
shu

Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone

doi: 10.16766/j.cnki.issn.1674-4152.003526

  • Department of Head and Neck Oncology Radiotherapy, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China

Funds:

 2020KY467

 2022KY695

  • Received Date: 2023-11-19
    Available Online: 2024-07-20
    Abstract
  •   Objective  To understand the current status of symptom distress and potential categories of symptom characteristics in nasopharyngeal carcinoma patients after radiation therapy by a one-year follow-up of symptoms in nasopharyngeal carcinoma patients after intensity-modulated radiation therapy, and to explore the differences in symptom characteristics among different types of patients to provide strategies for clinical nurses to develop targeted and sustained symptom management.  Methods  Nasopharyngeal carcinoma patients undergoing intensity-modulated radiation therapy and completing radiation therapy after one year were selected in Zhejiang Cancer Hospital from January 2020 to December 2022. General information questionnaire and QLQ. H&N35 were utilized as the investigating tools. Latent class analysis (LCA)was used to explore the latent classes of the symptom characteristics of nasopharyngeal carcinoma patients, and the general characteristics of different types of patients were analyzed.  Results  A total of 156 patients were selected. The symptoms with a high incidence rate were hyposexuality (52.6%), dry mouth (50.6%), and dental problems (39.7%) one year after radiotherapy in nasopharyngeal carcinoma patients. Among them, the severity of dry mouth [2.00 (1.0, 2.0) points] and hyposexuality [1.5 (1.0, 2.0) points] were higher. The symptom characteristics of nasopharyngeal carcinoma patients could be divided into three latent classes, which were named low symptom response group (77.56%), high physical symptoms response group (12.18%), and emotional psychological distress group (10.26%). One-way ANOVA showed that there were significant differences in education level, BMI, and radiation therapy methods among the three types.  Conclusion  The symptoms of nasopharyngeal carcinoma patients receiving intensity-modulated radiation therapy during home rehabilitation include three latent classes. Medical workers should identify the latent class to provide continuous symptom follow-up management and psychological counseling intervention for patients, reduce the physical and mental symptoms of patients and psychological counseling interventions, improve the quality of life of patients during home rehabilitation, and promote rehabilitation.

     

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