Volume 22 Issue 5
May  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(5): 882-886
ZHU Yunxia, YANG Can, WANG Hemei, CHEN Zengli, FEI Zhenzhen. Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone[J]. Chinese Journal of General Practice, 2024, 22(5): 882-886. doi: 10.16766/j.cnki.issn.1674-4152.003526
Citation: ZHU Yunxia, YANG Can, WANG Hemei, CHEN Zengli, FEI Zhenzhen. Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone[J]. Chinese Journal of General Practice, 2024, 22(5): 882-886. doi: 10.16766/j.cnki.issn.1674-4152.003526
shu

Latent class analysis of symptom characteristics of nasopharyngeal carcinoma patients receiving intensity modulated radiation therapy during rehabilitation periodone

doi: 10.16766/j.cnki.issn.1674-4152.003526

  • Department of Head and Neck Oncology Radiotherapy, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China

Funds:

 2020KY467

 2022KY695

  • Received Date: 2023-11-19
    Available Online: 2024-07-20
    Abstract
  •   Objective  To understand the current status of symptom distress and potential categories of symptom characteristics in nasopharyngeal carcinoma patients after radiation therapy by a one-year follow-up of symptoms in nasopharyngeal carcinoma patients after intensity-modulated radiation therapy, and to explore the differences in symptom characteristics among different types of patients to provide strategies for clinical nurses to develop targeted and sustained symptom management.  Methods  Nasopharyngeal carcinoma patients undergoing intensity-modulated radiation therapy and completing radiation therapy after one year were selected in Zhejiang Cancer Hospital from January 2020 to December 2022. General information questionnaire and QLQ. H&N35 were utilized as the investigating tools. Latent class analysis (LCA)was used to explore the latent classes of the symptom characteristics of nasopharyngeal carcinoma patients, and the general characteristics of different types of patients were analyzed.  Results  A total of 156 patients were selected. The symptoms with a high incidence rate were hyposexuality (52.6%), dry mouth (50.6%), and dental problems (39.7%) one year after radiotherapy in nasopharyngeal carcinoma patients. Among them, the severity of dry mouth [2.00 (1.0, 2.0) points] and hyposexuality [1.5 (1.0, 2.0) points] were higher. The symptom characteristics of nasopharyngeal carcinoma patients could be divided into three latent classes, which were named low symptom response group (77.56%), high physical symptoms response group (12.18%), and emotional psychological distress group (10.26%). One-way ANOVA showed that there were significant differences in education level, BMI, and radiation therapy methods among the three types.  Conclusion  The symptoms of nasopharyngeal carcinoma patients receiving intensity-modulated radiation therapy during home rehabilitation include three latent classes. Medical workers should identify the latent class to provide continuous symptom follow-up management and psychological counseling intervention for patients, reduce the physical and mental symptoms of patients and psychological counseling interventions, improve the quality of life of patients during home rehabilitation, and promote rehabilitation.

     

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    • References(23)
  • [1]
    何美霖, 易俊林. 复发鼻咽癌治疗现状[J]. 中华放射肿瘤学杂志, 2021, 30(11): 1202-1208. doi: 10.3760/cma.j.cn113030-20200220-00065

    HE M L, YI J L. Current treatment of recurrent nasopharngeal carcinoma[J]. Chinese Journal of Radiation Oncology, 2021, 30(11): 1202-1208. doi: 10.3760/cma.j.cn113030-20200220-00065
    [2]
    邱丽燕, 杨丽, 廖婷婷, 等. 鼻咽癌出院5年患者症状群与生活质量的相关性研究[J]. 护理学杂志, 2021, 36(3): 38-41. doi: 10.3870/j.issn.1001-4152.2021.03.038

    QIU L Y, YANG L, LIAO T T, et al. Correlation between symptom clusters and quality of life in patients with nasopharyngeal carcinoma after 5 years of discharge[J]. Journal of Nursing, 2021, 36(3): 38-41. doi: 10.3870/j.issn.1001-4152.2021.03.038
    [3]
    邱丽燕, 杨丽, 廖婷婷, 等. 鼻咽癌出院5年患者症状困扰现状及其影响因素分析[J]. 中国护理管理, 2020, 20(9): 1334-1339. doi: 10.3969/j.issn.1672-1756.2020.09.011

    QIU L Y, YANG L, LIAO T T, et al. Symptom distress and its influencing factors of nasopharyngeal carcinoma after 5 years of discharge[J]. Chinese Nursing Management, 2020, 20(9): 1334-1339. doi: 10.3969/j.issn.1672-1756.2020.09.011
    [4]
    李家燕, 杨丽, 张妍欣, 等. 鼻咽癌同步放化疗患者症状困扰纵向调查及影响因素分析[J]. 中国护理管理, 2021, 21(9): 1314-1320. doi: 10.3969/j.issn.1672-1756.2021.09.009

    LI J Y, YANG L, ZHANG Y X, et al. Longitudinal investigation and analysis of symptom distress and influencing factors in nasopharyngeal carcinoma patients with concurrent radiotherapy and chemotherapy[J]. Chinese Nursing Management, 2021, 21(9): 1314-1320. doi: 10.3969/j.issn.1672-1756.2021.09.009
    [5]
    ACHTERHOF R, HUNTJENS R J C, MEEWISSE M L, et al. Assessing the application of latent class and latent profile analysis for evaluating the construct validity of complex posttraumatic stress disorder: cautions and limitations[J]. Eur J Psychotraumatol, 2019, 10(1): 1-11.
    [6]
    李艺敏, 张玉晶, 李贻阳, 等. 早期结外NK/T细胞淋巴瘤鼻型患者根治性放疗后生存质量分析[J]. 中华放射肿瘤学杂志, 2022, 31(9): 798-804. doi: 10.3760/cma.j.cn113030-20220113-00015

    LI Y M, ZHANG Y J, LI Y Y, et al. Quality of life in patients with early-stage extra-nodal NK/T cell lymphoma of nasal type after definitive radiation therapy[J]. Chinese Journal of Radiation Oncology, 2022, 31(9): 798-804. doi: 10.3760/cma.j.cn113030-20220113-00015
    [7]
    HUANG T L, TSAI M H, CHUANG H C, et al. Quality of life and survival outcome for patients with nasopharyngeal carcinoma treated by volumetric-modulated arc therapy versus intensity -modulated radiotherapy[J]. Radiat Oncol, 2020, 15(1): 84. doi: 10.1186/s13014-020-01532-4
    [8]
    VAN DER LAAN H P, VAN DEN BOSCH L, SCHUIT E, et al. Impact of radiation-induced toxicities on quality of life of patients treated for head and neck cancer[J]. Radiother Oncol, 2021, 160: 47-53. doi: 10.1016/j.radonc.2021.04.011
    [9]
    姚鑫, 文司棋, 沈媛媛, 等. 护士组织沉默现状及潜在剖面分析[J]. 中华护理杂志, 2023, 58(8): 921-928. doi: 10.3761/j.issn.0254-1769.2023.08.004

    YANG X, WEN S Q, SHEN Y Y, et al. Current status and latent profile analysis of nurses' organizational silence[J]. Chinese Journal of Nursing, 2023, 58(8): 921-928. doi: 10.3761/j.issn.0254-1769.2023.08.004
    [10]
    廖婷婷, 杨丽, 邱丽燕, 等. 鼻咽癌出院患者放疗毒副反应变化趋势研究[J]. 中国全科医学, 2020, 23(26): 3330-3336. doi: 10.12114/j.issn.1007-9572.2020.00.182

    LIAO T T, YANG L, QIU L Y, et al. Changes in toxic side effects of radiotherapy in discharged patients with nasopharyngeal carcinoma[J]. Chinese General Practice, 2020, 23(26): 3330-3336. doi: 10.12114/j.issn.1007-9572.2020.00.182
    [11]
    于青松. 基于患者报告结局建立鼻咽癌放射性口干评价体系的研究[D]. 重庆: 重庆医科大学, 2022.

    YU Q S. Study on the establishment of radioactive xerostomia evaluation system for nasopharyngeal carcinoma based on patient-reported outcomes[D]. Chongqing: Chongqing Medical University, 2022.
    [12]
    王琳, 包德荣, 徐笑飞, 等. 中医药治疗放射性口干症的研究进展[J]. 中国乡村医药, 2023, 30(10): 76-78. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYY202310039.htm

    ANG L, BAO D R, XU X F, et al. Research progress of traditional Chinese medicine in the treatment of radiation xerostomi[J]. Chinese Journal of Rural Medicine and Pharmacy, 2023, 30(10): 76-78. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYY202310039.htm
    [13]
    崔珍, 刘佳, 孙巧玉, 等. 局部晚期鼻咽癌螺旋断层放疗与常规调强放疗的剂量学比较及近期疗效分析[J]. 蚌埠医学院学报, 2021, 46(7): 887-892. https://www.cnki.com.cn/Article/CJFDTOTAL-BANG202107013.htm

    CUI Z, LIU J, SUN Q Y, et al. Dosimetric comparison and short-term efficacy analysis of helical tomotherapy and intensity-modulated radiotherapy for locally advanced nasopharyngeal carcinoma[J]. Journal of Bengbu Medical College, 2021, 46(7): 887-892. https://www.cnki.com.cn/Article/CJFDTOTAL-BANG202107013.htm
    [14]
    刘万阳, 许青. 螺旋断层放射治疗技术在头颈部肿瘤中的应用[J]. 中国医疗器械信息, 2022, 46(1): 52-54. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGQX202201011.htm

    LIU W Y, XU Q. Application of tomotherapy for head and neck tumors[J]. China Medical Device Information, 2022, 46(1): 52-54. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGQX202201011.htm
    [15]
    王巧玲, 赵小梅, 杨曼, 等. 鼻咽癌患者社交回避与苦恼的现状及其影响因素[J]. 广西医学, 2022, 44(21): 2522-2535. https://www.cnki.com.cn/Article/CJFDTOTAL-GYYX202221013.htm

    WANG Q L, ZHAO X M, YANG M, et al. Current status of social avoidance and distress in patients with nasopharyngeal carcinoma and its influencing factors[J]. Guangxi Medical Journal, 2022, 44(21): 2522-2535. https://www.cnki.com.cn/Article/CJFDTOTAL-GYYX202221013.htm
    [16]
    李爱寅, 姚艳, 姚继云, 等. 鼻咽癌患者出院后恐惧疾病进展现状及影响因素分析[J]. 护理实践与研究, 2021, 18(21): 3181-3184. doi: 10.3969/j.issn.1672-9676.2021.21.005

    LI A Y, YAO Y, YAO J Y, et al. Analysis of the status quo and influencing factors of the phobic diseases in patients with nasopharyngeal carcinoma after discharge[J]. Nursing Practice and Research, 2021, 18(21): 3181-3184. doi: 10.3969/j.issn.1672-9676.2021.21.005
    [17]
    杨玉颖, 莫福琴, 黄晓琳, 等. 青年鼻咽癌患者疾病进展恐惧现状及其与放疗后症状困扰的相关性研究[J]. 中国护理管理, 2023, 23(1): 126-130. https://www.cnki.com.cn/Article/CJFDTOTAL-GLHL202301025.htm

    YANG Y Y, MOU F Q, HUNAG X L, et al. Fear of disease progression and its correlation with post-radiotherapy symptom distress in young patients with nasopharyngeal[J]. Chinese Nursing Management, 2023, 23(1): 126-130. https://www.cnki.com.cn/Article/CJFDTOTAL-GLHL202301025.htm
    [18]
    陈超, 杨世威, 冯丽, 等. 乳腺癌化疗患者的焦虑抑郁及其与化疗毒副反应的相关性[J]. 现代肿瘤医学, 2024, 32(2): 270-276. https://www.cnki.com.cn/Article/CJFDTOTAL-SXZL202402012.htm

    CHEN C, YANG S W, FENG L, et al. Anxiety and depression of breast cancer patients undergoing chemotherapy and their correlation with chemotherapy side effects[J]. Modern Oncology, 2024, 32(2): 270-276. https://www.cnki.com.cn/Article/CJFDTOTAL-SXZL202402012.htm
    [19]
    何艳. 鼻咽癌患者调强放射治疗前后焦虑抑郁及生活质量与其生存率关系的纵向研究[D]. 广州: 南方医科大学, 2022.

    HE Y. A longitudinal study on the relationship between anxiety, depression, quality of life and survival rate in patients with nasopharyngeal carcinoma before and after intensity-modulated radiotherapy[D]. Guangzhou: Southern Medical University, 2022.
    [20]
    王华, 杨春连, 李亦建. 心理疏导干预对鼻咽癌放疗患者康复和生活质量的影响研究[J]. 反射疗法与康复学, 2020, 29(13): 139-141. https://www.cnki.com.cn/Article/CJFDTOTAL-WMIA201860230.htm

    WANG H, YANG C L, LI L J. Effect of psychological counseling intervention on rehabilitation and quality of life in patients with nasopharyngeal carcinoma radiotherapy[J]. Reflexology and Rehabilitation Medicine, 2020, 29(13): 139-141. https://www.cnki.com.cn/Article/CJFDTOTAL-WMIA201860230.htm
    [21]
    李颖斐, 刘玉瑶, 魏洁丽, 等. 鼻咽癌患者癌症复发恐惧水平及影响因素分析[J]. 中华全科医学, 2019, 17(9): 1443-1446. doi: 10.16766/j.cnki.issn.1674-4152.000965

    LI Y F, LIU Y Y, WEI J L, et al. Analysis of fear of cancer recurrence and contributory factors in patients with nasopharyngeal carcinoma[J]. Chinese Journal of General Practice, 2019, 17(9): 1443-1446. doi: 10.16766/j.cnki.issn.1674-4152.000965
    [22]
    张启富, 周开斌, 陈在娟, 等. 鼻咽癌放疗后常见并发症的发病机制与康复评定及治疗进展[J]. 中国耳鼻咽喉颅底外科杂志, 2023, 29(4): 102-107. https://www.cnki.com.cn/Article/CJFDTOTAL-ZEBY202304022.htm

    ZHANG Q F, ZHOU K B, CHEN Z J, et al. Pathogenesis and progress of rehabilitation treatment of common complications after radiotherapy for nasopharyngeal carcinoma[J]. Chinese Journal of Otorhinolaryngology-skull Base Surgery, 2023, 29(4): 102-107. https://www.cnki.com.cn/Article/CJFDTOTAL-ZEBY202304022.htm
    [23]
    岑洁, 杨丽. 鼻咽癌患者健康管理APP的应用效果[J]. 中国护理管理, 2019, 19(11): 1695-1701. https://www.cnki.com.cn/Article/CJFDTOTAL-GLHL201911028.htm

    CEN J, YANG L. Application effect of health management APP on patients with nasopharyngeal carcinoma[J]. Chinese Nursing Management, 2019, 19(11): 1695-1701. https://www.cnki.com.cn/Article/CJFDTOTAL-GLHL201911028.htm
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