Volume 22 Issue 6
Jun.  2024
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TANG Mingqiu, SHI Jianwei, ZHOU Liang, GONG Xin, SUN Chaojun, ZHOU Ying. Exploring comorbidity patterns in coronary heart disease patients in Jiading district of Shanghai based on medical big datasets[J]. Chinese Journal of General Practice, 2024, 22(6): 903-906. doi: 10.16766/j.cnki.issn.1674-4152.003531
Citation: TANG Mingqiu, SHI Jianwei, ZHOU Liang, GONG Xin, SUN Chaojun, ZHOU Ying. Exploring comorbidity patterns in coronary heart disease patients in Jiading district of Shanghai based on medical big datasets[J]. Chinese Journal of General Practice, 2024, 22(6): 903-906. doi: 10.16766/j.cnki.issn.1674-4152.003531

Exploring comorbidity patterns in coronary heart disease patients in Jiading district of Shanghai based on medical big datasets

doi: 10.16766/j.cnki.issn.1674-4152.003531
Funds:

 72204187

 2021SQ05

  • Received Date: 2023-11-26
    Available Online: 2024-07-22
  •   Objective  This study aims to explore the comorbidities associated with CHD and support its precise management.  Methods  Data on CHD patients from all medical institutions in Jiading District, Shanghai, from December 2020 to December 2021 were analyzed. The Apriori algorithm was used to identify key comorbidities, and 2-STEP clustering method was used to explore patterns of multimorbidity.  Results  Among 192 060 CHD patients, 166 969 (86.94%) exhibited comorbidities, with a higher rate in women (98 802, 87.18%) than in men (68 167, 86.59%, χ2=695.555, P < 0.001). The proportion of comorbidity increased significantly along with the age increase: 73.46% in the 18-60 age group (18 017), 86.94% in the 61-75 age group (87 180), and 91.85% in the over 75 age group (61 772, Z=-13.704, P < 0.001). CHD typically presents with 2-4 comorbidities, with hypertension (71.59%) and chronic gastroenteritis (49.96%) being the primary comorbidities identified through association rule analysis. Five distinct multimorbidity patterns were identified by 2-STEP clustering analysis: triggers, complications, cardiovascular-metabolic, circulatory system, and multi-system mixed.  Conclusion  CHD patients exhibit high comorbidity rates and diverse patterns of co-existing diseases, indicating the need for differentiated management strategies. These strategies should focus on proactive health measures, managing polypharmacy, and delaying progression to effectively address multimorbidity.

     

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