Volume 22 Issue 7
Jul.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(7): 1098-1101
ZHANG Lixia, ZHU Feng, LI Chuanjing, LIU Xianglei, KAN Yueyue, GUO Qingli. Early warning value and bronchoscopic characteristics of experimental indicators such as CRP and LDH in severe Mycoplasma pneumoniae[J]. Chinese Journal of General Practice, 2024, 22(7): 1098-1101. doi: 10.16766/j.cnki.issn.1674-4152.003575
Citation: ZHANG Lixia, ZHU Feng, LI Chuanjing, LIU Xianglei, KAN Yueyue, GUO Qingli. Early warning value and bronchoscopic characteristics of experimental indicators such as CRP and LDH in severe Mycoplasma pneumoniae[J]. Chinese Journal of General Practice, 2024, 22(7): 1098-1101. doi: 10.16766/j.cnki.issn.1674-4152.003575
shu

Early warning value and bronchoscopic characteristics of experimental indicators such as CRP and LDH in severe Mycoplasma pneumoniae

doi: 10.16766/j.cnki.issn.1674-4152.003575

  • Children's Respiratory Department of Suzhou Hospital Affiliated to Anhui Medical University, Suzhou, Anhui 234000, China

Funds:

 202304295107020119

 SZWJ2022a037

  • Received Date: 2024-01-12
    Available Online: 2024-09-05
    Abstract
  •   Objective  To explore the early warning value of experimental indicators for severe Mycoplasma pneumoniae pneumonia (SMPP) and the clinical characteristics under bronchoscopy, and provide reference for early diagnosis of SMPP.  Methods  The case data of children with Mycoplasma pneumoniae pneumonia (MPP) admitted to Suzhou Hospital Affiliated to Anhui Medical University from January to December 2023 was collected. According to the severity of the condition, they were divided into a severe group and a common group, with 40 cases randomly selected from each group. The differences in general conditions, experimental indicators, and bronchoscopy characteristics between the two groups were compared for statistical analysis.  Results  There was no statistically significant difference in the proportion of neutrophils and procalcitonin (PCT) between the two groups (P>0.05), while the severe group had higher levels of white blood cells (WBC), C-reactive protein (CRP), lactate dehydrogenase (LDH), and D-dimer (D-D) than the normal group (P < 0.05). Multivariate logistic regression analysis showed that WBC, CRP, LDH, and D-D were independent risk factors for SMPP (P < 0.05). ROC curve analysis showed that CRP, LDH, and D-D have high predictive value for the diagnosis of SMPP (P < 0.05), with the optimal thresholds of 19.42 mg/L, 361.00 IU/L, and 1.075 mg/L, respectively. The proportion of bronchoscopy, mucus emboli under bronchoscopy, and neutrophil count in lavage fluid in the severe group were higher than those in the normal group (P < 0.05).  Conclusion  CRP, LDH, and D-D are independent risk factors for SMPP. When CRP>19.42 mg/L, LDH>361.00 IU/L, and D-D>1.075 mg/L, it is helpful for early identification of SMPP. The proportion of mucus embolism under SMPP endoscopy is high, and active bronchoscopy treatment is needed. At the same time, the appearance of the lavage fluid is cloudy and the proportion of neutrophils is high, which can further evaluate the condition.

     

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