Volume 22 Issue 7
Jul.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(7): 1133-1137
WANG Lu, LI Xianhai, LIU Xiancui, XU Hao, ZHANG Liang. Effect of 3D printed titanium interbody fusion device combined with PRP-containing allograft bone in ACDF surgery[J]. Chinese Journal of General Practice, 2024, 22(7): 1133-1137. doi: 10.16766/j.cnki.issn.1674-4152.003583
Citation: WANG Lu, LI Xianhai, LIU Xiancui, XU Hao, ZHANG Liang. Effect of 3D printed titanium interbody fusion device combined with PRP-containing allograft bone in ACDF surgery[J]. Chinese Journal of General Practice, 2024, 22(7): 1133-1137. doi: 10.16766/j.cnki.issn.1674-4152.003583
shu

Effect of 3D printed titanium interbody fusion device combined with PRP-containing allograft bone in ACDF surgery

doi: 10.16766/j.cnki.issn.1674-4152.003583
  • 1.

    Department of Orthopaedics, Zhoushan Hospital Affiliated to Wenzhou Medical University, Zhoushan, Zhejiang 316000, China

Funds:

 2020ZB163

 2023C31009

  • Received Date: 2023-11-23
    Available Online: 2024-09-05
    Abstract
  •   Objective  This study analyzes the clinical outcomes of the combined application of 3D-printed titanium alloy intervertebral fusion devices and autologous bone treated with platelet-rich plasma (PRP) in anterior cervical discectomy and fusion (ACDF) procedures. It further assesses the potential benefits of this combination in promoting spinal stability and vertebral fusion.  Methods  From August 2021 to May 2023, 110 patients with cervical spondylosis who needed ACDF were selected. Among them, 56 patients with 3D printed interbody fusion cage were classified as Group A, and 54 patients with 3D printed interbody fusion cage combined with PRP allograft were classified as Group B. The operation time, intraoperative blood loss, postoperative drainage, Japanese Orthopedic Association (JOA) score, and visual simulated pain (VAS) score were observed, and the segmental angle (SA), cervical curvature index (CCI), intervertebral disc height (IH) and the fusion rate at each time point after operation were measured.  Results  There was no significant difference in operation time and blood loss between the two groups (P>0.05), and the postoperative drainage in group B was significantly less than that in group A (P < 0.05). There were statistical differences in VAS score and JOA score evaluated at different times (P < 0.05). There were statistical differences in SA, CCI, and IH measured at different times (P < 0.05). The X-ray of the cervical spine showed that the imaging fusion rates of group A and group B were 48.21% (27/56) and 70.37% (38/54) at 3 months after operation, 73.21% (41/56) and 92.59% (50/54) at 6 months after operation, and 100.00% at 12 months after operation. The fusion rates of group B at 3 months and 6 months after operation were significantly higher than those of group A (P < 0.05).  Conclusion  The use of a 3D printed interbody fusion cage combined with PRP-containing allogenic bone in ACDF has the advantage of less postoperative drainage, which can also promote early fusion and improve the success rate of fusion surgery.

     

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