Correlation analysis between hyperuricemia and chronic metabolic diseases in the elderly population from the community perspective

GU Ruying; LI Juan; CHEN Yan; WANG Zhaoxin

doi:10.16766/j.cnki.issn.1674-4152.003617

Volume 22 Issue 8

Aug. 2024

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Article Navigation > Chinese Journal of General Practice > 2024 > 22(8): 1283-1286

GU Ruying, LI Juan, CHEN Yan, WANG Zhaoxin. Correlation analysis between hyperuricemia and chronic metabolic diseases in the elderly population from the community perspective[J]. Chinese Journal of General Practice, 2024, 22(8): 1283-1286. doi: 10.16766/j.cnki.issn.1674-4152.003617

Citation:

GU Ruying, LI Juan, CHEN Yan, WANG Zhaoxin. Correlation analysis between hyperuricemia and chronic metabolic diseases in the elderly population from the community perspective[J]. Chinese Journal of General Practice, 2024, 22(8): 1283-1286. doi: 10.16766/j.cnki.issn.1674-4152.003617

Citation:

GU Ruying, LI Juan, CHEN Yan, WANG Zhaoxin. Correlation analysis between hyperuricemia and chronic metabolic diseases in the elderly population from the community perspective[J]. Chinese Journal of General Practice, 2024, 22(8): 1283-1286. doi: 10.16766/j.cnki.issn.1674-4152.003617

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Correlation analysis between hyperuricemia and chronic metabolic diseases in the elderly population from the community perspective

doi: 10.16766/j.cnki.issn.1674-4152.003617

GU Ruying^{1
,
,}
, LI Juan¹
, CHEN Yan¹
, WANG Zhaoxin²

1.
Minhang District Hongqiao Community Healthcare Center, Shanghai Medical College,Fudan University, Shanghai 201103, China

Funds:

2022YFC3601505

Received Date: 2024-03-11
Available Online: 2024-11-19

Abstract

Abstract

Objective To analyze the current status of hyperuricemia (HUA) in the elderly population in the community, explore the critical value of HUA, and the correlation between serum uric acid levels and chronic metabolic diseases. Methods A cross-sectional study was conducted on 1 508 elderly individuals who participated in physical examinations in two communities in Minhang District, Shanghai in 2023. The main outcome measures were serum uric acid, fasting plasma glucose (FPG), glycated haemoglobin (HbA1c), and blood lipid detection. Height, weight, waist circumference, and blood pressure were also measured. HUA was defined as serum uric acid >420 μmol/L in males and >360 μmol/L in females. Results The estimated prevalence in this population was 26.8% (404/1 508, 95% CI: 24.6%-29.1%) overall, 24.7% (182/736) in males and 28.8% (222/772) in females. The prevalence of males and females increased with age, and the incidence of chronic metabolic diseases in HUA groups was significantly higher than those in non-HUA groups. There was no statistically significant difference in the proportion of chronic metabolic diseases among females with different serum uric acid levels in HUA. Multivariate regression analysis showed that hypertension (OR_male=1.847, 95% CI: 1.209-2.820; OR_female=1.519, 95% CI: 1.009-2.288), high values of TG (OR_male=1.296, 95% CI: 1.100-1.527; OR_female=1.619, 95% CI: 1.316-1.991) were the strong risk factors for HUA, and BMI was positively correlated with uric acid levels. Conclusion The prevalence of HUA among the elderly population in the Community is relatively high. Hypertension and high values of TG are strong risk factors for HUA. Females with serum uric acid > 360 μmol/L are associated with a higher proportion of chronic metabolic diseases. It is recommended to control the target level of serum uric acid in Females to be less than 360 μmol/L.
- Hyperuricemia,
- The aged,
- Chronic metabolic diseases,
- Related factor

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References(22)

References

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Correlation analysis between hyperuricemia and chronic metabolic diseases in the elderly population from the community perspective

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