Volume 23 Issue 1
Jan.  2025
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LIU Jie, HAN Peng, SUI Fang, YAN Jinfeng, ZHANG Xiping, HOU Huan, BI Ying. Meta-analysis of preoperative oral carbohydrate effects in patients with thyroidectomy[J]. Chinese Journal of General Practice, 2025, 23(1): 143-147. doi: 10.16766/j.cnki.issn.1674-4152.003854
Citation: LIU Jie, HAN Peng, SUI Fang, YAN Jinfeng, ZHANG Xiping, HOU Huan, BI Ying. Meta-analysis of preoperative oral carbohydrate effects in patients with thyroidectomy[J]. Chinese Journal of General Practice, 2025, 23(1): 143-147. doi: 10.16766/j.cnki.issn.1674-4152.003854

Meta-analysis of preoperative oral carbohydrate effects in patients with thyroidectomy

doi: 10.16766/j.cnki.issn.1674-4152.003854
Funds:

 2022JQ-834

  • Received Date: 2024-01-22
    Available Online: 2025-02-13
  •   Objective   To evaluate the efficacy and safety of preoperative oral carbohydrate in patients with thyroidectomy during the perioperative period by meta-analysis, and to guide the clinical implementation.   Methods   CNKI, VIP, Wanfang, PubMed, Embase, Web of Science, Wiley Online Library, and other Chinese and English databases were used to search related RCT. The retrieval period was from the establishment of the database to March 21, 2021. According to the inclusion and exclusion criteria, literature screening and data extraction were conducted independently by two researchers. RevMan software (version 5.3) was used for literature quality evaluation and meta-analysis.   Results   Sixteen randomized controlled trials involving 1 793 patients were included in the study. The experimental group was given oral carbohydrate before surgery, while the control group was given a conventional diet before surgery, The results showed as follows: preoperative indexes of dry mouth and thirst [95% CI (-2.39, -0.47), P=0.003], postoperative indexes of nausea and vomiting [95% CI (0.41, 0.80), P=0.001], indexes of insulin resistance [95% CI (-2.73, -0.69), P=0.001], the first time to get out of bed after surgery [95% CI (-1.56, -0.87), P < 0.01], the first time to eat after surgery [95% CI (-1.07, -0.13), P=0.010], the number of hospitalization days [95% CI (-2.67, -1.55), P < 0.01], and the number of postoperative complications [95% CI (0.08, 0.32), P < 0.01], indicating that the experimental group was better than the control group (P < 0.05).   Conclusion   Compared with conventional care, preoperative oral carbohydrate is safe and beneficial in the perioperative period of patients with thyroidectomy, and has good clinical application value.

     

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