Volume 23 Issue 3
Mar.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(3): 365-368
AN Yan, ZU Fei, DONG Xuejie, YU Ping, ZHU Wei. Research on the clinical application of flash glucose monitoring system in blood glucose management during pregnancy[J]. Chinese Journal of General Practice, 2025, 23(3): 365-368. doi: 10.16766/j.cnki.issn.1674-4152.003905
Citation: AN Yan, ZU Fei, DONG Xuejie, YU Ping, ZHU Wei. Research on the clinical application of flash glucose monitoring system in blood glucose management during pregnancy[J]. Chinese Journal of General Practice, 2025, 23(3): 365-368. doi: 10.16766/j.cnki.issn.1674-4152.003905
shu

Research on the clinical application of flash glucose monitoring system in blood glucose management during pregnancy

doi: 10.16766/j.cnki.issn.1674-4152.003905
  • 1.

    Department of Endocrinology, Beijing Aerospace General Hospital, Beijing 100076, China

Funds:

 10025220109

  • Received Date: 2024-10-14
    Available Online: 2025-05-14
    Abstract
  •   Objective  To apply the 28-day flash glucose monitoring (FGM) system to gestational diabetes mellitus (GDM) patients undergoing insulin therapy, observe the impact of FGM on blood glucose management and pregnancy outcomes, and provide evidence for the selection of better blood glucose monitoring methods in clinical practice.  Methods  The study subjects were 98 patients diagnosed with GDM and receiving insulin therapy at Beijing Aerospace General Hospital from April to October 2022. They were divided into the FGM group (49 cases) and the self-monitoring of blood glucose (SMBG) group (49 cases) using a random number table method. The fasting blood glucose (FBG), 2-hour plasma glucose (2hPG), mean blood glucose (MBG), estimated glycated hemoglobin (eHbA1c), time to target blood glucose (TIR), incidence of hypoglycemia, weight compliance and pregnancy outcome were compared between the two groups.  Results  The levels of MBG and eHbA1c in FGM group were significantly lower than those in SMBG group (P < 0.05), but there was no statistical significance in FBG, 2hPG and TIR (P > 0.05). The weight control rate during pregnancy in the FGM group was significantly higher than that in the SMBG group [61.22% (30/49) vs. 40.82% (20/49), P < 0.05]. The incidence of cesarean section, premature birth, prelabor rupture of membranes, and macrosomia among pregnant women in the FGM group were significantly lower than those in the SMBG group (P < 0.05). Logistic regression analysis revealed that underweight during pregnancy was an independent risk factor for adverse pregnancy outcomes, including cesarean section and preterm birth (OR=14.639, 95% CI: 1.747-122.655, P=0.013).  Conclusion  The application of FGM system can help achieve ideal blood glucose control and weight control, reducing the risk of adverse pregnancy outcomes.

     

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    • References(21)
  • [1]
    徐嘉蔚, 林萱. 妊娠期糖尿病的研究进展[J]. 临床内科杂志, 2023, 40(10): 716-718. doi: 10.3969/j.issn.1001-9057.2023.10.020

    XU J H, LIN X. Research progress in gestational diabetes[J]. Journal of Clinical Internal Medicine, 2023, 40(10): 716-718. doi: 10.3969/j.issn.1001-9057.2023.10.020
    [2]
    郑凯, 袁晶. 脂肪因子与妊娠期糖尿病及糖脂代谢[J]. 国际生殖健康/计划生育杂志, 2021, 40(5): 431-435.

    ZHENG K, YUAN J. Adipokines and gestational diabetes mellitus and glucose lipid metabolism[J]. Journal of International Reproductive Health/Family Planning, 2021, 40(5): 431-435.
    [3]
    刘莎莎, 赵云, 孙国强, 等. 妊娠期糖尿病患者胎盘组织中Apelin和APJ的表达及其对滋养层细胞胰岛素抵抗和行为的影响[J]. 吉林大学学报(医学版), 2022, 48(5): 1314-1323.

    LIU S S, ZHAO Y, SUN G Q, et al. Expressions of Apelin and APJ in placental tissue of gestational diabetes mellitus patients and its effect on insulin resistance and behavior of trophoblast cells[J]. Journal of Jilin University: Medicine Edition, 2022, 48(5): 1314-1323.
    [4]
    邱青梅, 梁莉, 陆洁清, 等. 妊娠期糖尿病患者孕期增重情况调查及对母婴并发症发生率影响[J]. 临床军医杂志, 2023, 51(1): 86-88.

    QIU Q M, LIANG L, LU J Q, et al. Investigation of gestational weight gain in patients with gestational diabetes mellitus and its impact on the incidence of maternal and infant complications[J]. Clinical Journal of Medical Officers, 2023, 51(1): 86-88.
    [5]
    中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)[J]. 中华糖尿病杂志, 2021, 13(4): 315-409.

    Chinese Society of Diabetes. Guidelines for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition)[J]. Chinese Journal of Diabetes Mellitus, 2021, 13(4): 315-409.
    [6]
    王倩, 陈琳, 谢克亮. 血糖监测技术及管理指标的临床应用进展[J]. 实用检验医师杂志, 2022, 14(3): 332-336. doi: 10.3969/j.issn.1674-7151.2022.03.027

    WANG Q, CHEN L, XIE K L. Clinical application progress of blood glucose monitoring technology and management indicators[J]. Chinese Journal of Clinical Pathologist, 2022, 14(3): 332-336. doi: 10.3969/j.issn.1674-7151.2022.03.027
    [7]
    隽娟, 孙祎赢, 叶彩云, 等. 妊娠期糖尿病合并慢性高血压孕妇胰岛素抵抗水平及其对妊娠结局的影响[J]. 中华围产医学杂志, 2020, 23(2): 91-97. doi: 10.3760/cma.j.issn.1007-9408.2020.02.004

    JUAN J, SUN Y Y, YE C Y, et al. Insulin resistance and pregnancy outcomes in gestational diabetes mellitus gravida complicated by chronic hypertension[J]. Chinese Journal of Perinatal Medicine, 2020, 23(2): 91-97. doi: 10.3760/cma.j.issn.1007-9408.2020.02.004
    [8]
    于春梅, 李武珊, 王青. 妊娠糖尿病孕妇胰岛素相关指标水平变化及临床意义[J]. 国际医药卫生导报, 2023, 29(17): 2459-2462. doi: 10.3760/cma.j.issn.1007-1245.2023.17.020

    YU C M, LI W S, WANG Q. Changes and clinical significance of insulin related indexes in pregnant women with gestational diabetes mellitus[J]. International Medicine and Health Guidance News, 2023, 29(17): 2459-2462. doi: 10.3760/cma.j.issn.1007-1245.2023.17.020
    [9]
    WANG N, SONG L, SUN B. Contribution of gestational diabetes mellitus heterogeneity and prepregnancy body mass index to large-for-gestational-age infants: a retrospective case-control study[J]. J Diabetes, 2021, 13(4): 307-317. doi: 10.1111/1753-0407.13113
    [10]
    ELLERBROCK J, SPAANDERMAN B, DRONGELEN J V, et al. Role of beta cell function and insulin resistance in the development of gestational diabetes mellitus[J]. Nutrients, 2022, 14(12): 2444. DOI: 10.3390/nu14122444.
    [11]
    BATTELINO T, DANNE T, BERGENSTAL R M, et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range[J]. Diabetes Care, 2019, 42(8): 1593-1603. doi: 10.2337/dci19-0028
    [12]
    中华医学会妇产科学分会产科学组, 中华医学会围产医学分会, 中国妇幼保健协会妊娠合并糖尿病专业委员会. 妊娠期高血糖诊治指南(2022)[第二部分] [J]. 中华妇产科杂志, 2022, 57(2): 81-90. doi: 10.3760/cma.j.cn112141-20210917-00529

    Chinese Medical Association Obstetrics and Gynecology Branch, Chinese Medical Association Perinatal Medicine branch, China Maternal and Child Health Association pregnancy and diabetes professional Committee. Guideline of diagnosis and treatment of hyperglycemia in pregnancy(2022)[Part two] [J]. Chinese Journal of Obstetrics and Gynecology, 2022, 57(2): 81-90. doi: 10.3760/cma.j.cn112141-20210917-00529
    [13]
    中华医学会糖尿病学分会. 中国血糖监测临床应用指南(2021年版)[J]. 中华糖尿病杂志, 2021, 13(10): 936-948. doi: 10.3760/cma.j.cn115791-20210810-00436

    Chinese Diabetes Society. Clinical application guideline for blood glucose monitoring in China (2021 edition)[J]. Chinese Journal of Diabetes Mellitus, 2021, 13(10): 936-948. doi: 10.3760/cma.j.cn115791-20210810-00436
    [14]
    YARON M, ROITMAN E, AHARON-HANANEL G, et al. Effect of flash glucose monitoring technology on glycemic control and treatment satisfaction in patients with type 2 diabetes[J]. Diabetes Care, 2019, 42(7): 1178-1184. doi: 10.2337/dc18-0166
    [15]
    龚莉, 赵晶, 陈曙新. 高龄妊娠糖尿病危险因素及其母婴结局分析[J]. 中华全科医学, 2022, 20(12): 2068-2070, 2074. doi: 10.16766/j.cnki.issn.1674-4152.002771

    GONG L, ZHAO J, CHEN S X. Risk factors of gestational diabetes mellitus in advanced age and analysis of maternal and infant outcomes[J]. Chinese Journal of General Practice, 2022, 20(12): 2068-2070, 2074. doi: 10.16766/j.cnki.issn.1674-4152.002771
    [16]
    YE W R, LUO C, HUANG J. Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis[J]. BMJ, 2022, 25(377): e067946. DOI: 10.1136/bmj-2021-067946.
    [17]
    陆艳萍, 周莹, 臧丽娟. 妊娠期糖尿病患者血糖波动幅度对母婴结局的影响[J]. 中国妇幼保健, 2022, 37(3): 412-415.

    LU Y P, ZHOU Y, ZANG L J. Effect of blood glucose fluctuation in patients with gestational diabetes mellitus on maternal and infant outcomes[J]. Maternal and Child Health Care of China, 2022, 37(3): 412-415.
    [18]
    陈云燕, 吴琪, 张丽霞, 等. 妊娠糖尿病孕妇孕中期口服葡萄糖耐量试验异常项数及孕期增重与不良妊娠结局的关系[J]. 浙江大学学报(医学版), 2021, 50(3): 313-319.

    CHEN Y Y, WU Q, ZHANG L X, et al. Relationship of abnormal mid-term oral glucose tolerance test and maternal weight gain with adverse pregnancy outcomes in women with gestational diabetes mellitus[J]. Journal of Zhejiang University (Medical Sciences), 2021, 50(3): 313-319.
    [19]
    王薇, 黄婵, 顾华妍, 等. 围孕期空腹血糖对妊娠期糖尿病发生的预测作用及其与不良妊娠结局的关系[J]. 实用妇产科杂志, 2023, 39(2): 142-146.

    WANG W, HUANG C, GU H Y, et al. Predictive effect of fasting blood glucose during pregnancy on the occurrence of gestational diabetes mellitus and its relationship with adverse pregnancy outcomes[J]. Journal of Practical Obstetrics and Gynecology, 2023, 39(2): 142-146.
    [20]
    唐艺, 查红英, 孙璐, 等. 妊娠期糖尿病患者口服葡萄糖耐量试验不同时间点血糖特征与妊娠结局相关性的研究[J]. 中国糖尿病杂志, 2023, 31(7): 491-499. doi: 10.3969/j.issn.1006-6187.2023.07.003

    TANG Y, ZHA H Y, SUN L, et al. Associations between blood glucose characteristics based on OGTT values and pregnancy outcomes in gestational diabetes mellitus[J]. Chinese Journal of Diabetes, 2023, 31(7): 491-499. doi: 10.3969/j.issn.1006-6187.2023.07.003
    [21]
    杨严政, 周玉娥, 李团, 等. 孕前体质指数、孕期血红蛋白水平及孕期体重增长对妊娠结局的影响[J]. 昆明医科大学学报, 2022, 43(11): 112-117. doi: 10.12259/j.issn.2095-610X.S20221103

    YANG Y Z, ZHOU Y E, LI T, et al. Effects of prepregnancy body mass index, hemoglobin and gestational weight gain on pregnancy outcomes[J]. Journal of Kunming Medical University, 2022, 43(11): 112-117. doi: 10.12259/j.issn.2095-610X.S20221103
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