Volume 23 Issue 3
Mar.  2025
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WANG Cong*, FAN Kaikai, LIU Hongfeng, WANG Xiyong. Evaluation and application of rational drug use for fat emulsion, amino acids (17) and glucose (11%) injection based on AHP-TOPSIS method[J]. Chinese Journal of General Practice, 2025, 23(3): 397-400. doi: 10.16766/j.cnki.issn.1674-4152.003912
Citation: WANG Cong*, FAN Kaikai, LIU Hongfeng, WANG Xiyong. Evaluation and application of rational drug use for fat emulsion, amino acids (17) and glucose (11%) injection based on AHP-TOPSIS method[J]. Chinese Journal of General Practice, 2025, 23(3): 397-400. doi: 10.16766/j.cnki.issn.1674-4152.003912
shu

Evaluation and application of rational drug use for fat emulsion, amino acids (17) and glucose (11%) injection based on AHP-TOPSIS method

doi: 10.16766/j.cnki.issn.1674-4152.003912
  • 1.

    *Department of Pharmacy, Suzhou Hospital of Anhui Medical University, Suzhou, Anhui 234000, China

Funds:

 KJ2020A1145

  • Received Date: 2024-03-01
    Available Online: 2025-05-14
    Abstract
  •   Objective  To by constructing the drug utilisation evaluation (DUE) standard of fat emulsion, amino acids (17) and glucose (11%) injection, it provides a reference basis for the rational use of medication in the clinic.  Methods  A total of 255 medical records of fat emulsion, amino acids (17) and glucose (11%) injection from January to December 2023 in Suzhou Hospital of Anhui Medical University were selected by simple random sampling, and the evidence-based medical data, guidelines, expert consensus and drug instructions related to fat emulsion, amino acids (17) and glucose (11%) injection were used as the theoretical basis to establish DUE criteria for our hospital. The weight coefficients of each index were calculated by the hierarchical analysis (AHP) method, and the data of the patients who applied fat emulsion, amino acids (17) and glucose (11%) injection were retrospectively analysed and evaluated by the method of technique for order preference by similarity to an ideal solution (TOPSIS), and the evaluation results were classified into three levels of irrationality of the medication, basic rationality of the medication, and reasonableness of the medication according to the distribution of the relative proximity (Ci).  Results  The evaluation results of 255 patients applying fat emulsion, amino acids (17) and glucose (11%) injection by the AHP method combined with the TOPSIS method showed a low rate of rationality in the prescription of fat emulsion, amino acids (17) and glucose (11%) injection, of which 67 cases (Ci≥0.8, 26.27%) were reasonably medicated, 37 cases (0.6 ≤Ci < 0.8, 14.51%) medication was basically reasonable, and 151 cases (Ci < 0.6, 59.22%) were unreasonably medicated; the main problems of unreasonable medication were focused on indications for medication, timing of medication, nutritional assessment, monitoring of medication, combination of medication and contraindications.  Conclusion  The AHP-TOPSIS method was used to establish the DUE criteria for the clinical application of fat emulsion, amino acids (17) and glucose (11%) injection, which is presented in the form of quantifiable data, and its evaluation results are scientific, reasonable, intuitive and credible, which can objectively reflect the use of fat emulsion, amino acids (17) and glucose (11%) injection. The study found that there are still many unreasonable phenomena in the clinical application of this drug, and it is necessary to formulate effective measures to intervene and strengthen the management, so as to find out the problems and make improvements.

     

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