Volume 23 Issue 3
Mar.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(3): 464-467
SHAO Chunhui, LI Peiying, ZHAO Junzhi, LUO Yongke, LYU Pin, ZHANG Yi. The value of multimodal ultrasound in the diagnosis of C-TIRADS4 fine needle aspiration cytology for TBSRTC Type Ⅲ thyroid nodules[J]. Chinese Journal of General Practice, 2025, 23(3): 464-467. doi: 10.16766/j.cnki.issn.1674-4152.003928
Citation: SHAO Chunhui, LI Peiying, ZHAO Junzhi, LUO Yongke, LYU Pin, ZHANG Yi. The value of multimodal ultrasound in the diagnosis of C-TIRADS4 fine needle aspiration cytology for TBSRTC Type Ⅲ thyroid nodules[J]. Chinese Journal of General Practice, 2025, 23(3): 464-467. doi: 10.16766/j.cnki.issn.1674-4152.003928
shu

The value of multimodal ultrasound in the diagnosis of C-TIRADS4 fine needle aspiration cytology for TBSRTC Type Ⅲ thyroid nodules

doi: 10.16766/j.cnki.issn.1674-4152.003928
  • 1.

    Department of Ultrasound Medicine, Baoji People ' s Hospital, Baoji, Shaanxi 721000, China

Funds:

 2023-YBSF-011

 2024-052

  • Received Date: 2024-07-15
    Abstract
  •   Objective  Exploring the diagnostic value of multimodal ultrasound quantitative parameters in the classification of thyroid C-TIRADS4 nodules FNAC as TBSRTC Ⅲ nodules.  Methods  A total of 126 thyroid C-TIRADS4 type FNAC specimens confirmed by surgical pathology in Baoji People ' s Hospital from January 2023 to January 2024 were selected as TBSRTC type Ⅲ nodules by contrast ultrasonography and elastic imaging, FNAC cytological images and postoperative pathological results. Postoperative pathological results were used as grouping criteria, including 83 nodules in the malignant group and 43 nodules in the benign group. CEUS parameters (PI, TIC-AUC), SE parameters (SEmean, SR), and SWE parameters (Emean, ER) were used to compare the differences between the two groups. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of each parameter and the diagnostic efficiency of multi-mode ultrasound combined application.  Results  The mean values of PI, TIC-AUC, and SEmean in the benign group were higher than those in the malignant group (P < 0.05), while SR, Emean, and ER were lower than those in the malignant group (P < 0.05). The AUC (95% CI), sensitivity, specificity, and Youden index of multimodal ultrasound diagnosis were 0.912 (0.849-0.955), 96.39%, 86.05%, and 0.824, respectively, which were significantly higher than that of single ultrasound diagnosis mode. PI and TIC-AUC were pairwise compared with ROC curves of multi-mode ultrasound, and there were statistically significant differences between multi-mode ultrasound vs. PI and multi-mode ultrasound vs. TIC-AUC (Z=2.750, 2.293, P < 0.05).  Conclusion  The quantitative parameters of multimodal ultrasound can improve the diagnostic value of C-TIRADS4 type FNAC examination and pathological diagnosis of TBSRTC type Ⅲ thyroid nodules.

     

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